Sakda Daduang

ORCID: 0000-0003-2672-7710
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Research Areas
  • Antimicrobial Peptides and Activities
  • Venomous Animal Envenomation and Studies
  • Insect and Pesticide Research
  • Aquaculture disease management and microbiota
  • Advanced biosensing and bioanalysis techniques
  • Protein Hydrolysis and Bioactive Peptides
  • Biochemical and Structural Characterization
  • Healthcare and Venom Research
  • Burkholderia infections and melioidosis
  • Enzyme Production and Characterization
  • Electrochemical sensors and biosensors
  • Food Allergy and Anaphylaxis Research
  • Lipid Membrane Structure and Behavior
  • Insect and Arachnid Ecology and Behavior
  • Toxin Mechanisms and Immunotoxins
  • Neurobiology and Insect Physiology Research
  • Nanoparticles: synthesis and applications
  • Biosensors and Analytical Detection
  • Electrochemical Analysis and Applications
  • Aquaculture Nutrition and Growth
  • Biological Stains and Phytochemicals
  • Phytase and its Applications
  • Allergic Rhinitis and Sensitization
  • Turtle Biology and Conservation
  • Pineapple and bromelain studies

Khon Kaen University
2016-2025

Mae Fah Luang University
2020

Medical Diagnostic Laboratories (United States)
2020

Pharmaceutical Biotechnology (Czechia)
2015

Osaka University
2006

The University of Tokyo
1995-1998

Tokyo University of Science
1998

Abstract Background Diagnostic tests for fish allergy are hampered by the large number of under‐investigated species. Four salmon allergens well‐characterized and registered with WHO/IUIS while no catfish have been described so far. In 2008, freshwater‐cultured production surpassed that salmon, globally most‐cultured marine We aimed to identify, quantify, compare all IgE‐binding proteins in catfish. Methods Seventy‐seven pediatric patients clinically confirmed underwent skin prick The...

10.1111/all.14574 article EN Allergy 2020-08-29

In this work, cellulose nanofibers and graphene oxide are used to fabricate a simple reliable electrochemical biosensor, based on acetylcholinesterase (AChE) for the detection of highly dangerous organophosphates (OPs), utilizing chlorpyrifos as representative sample. AChE is an enzyme that essential neurotransmission catalyzes conversion acetylcholine (ATCh) into thiocholine acetic acid. The pesticide in chlorpyrifos, inhibits catalytic activity ATCh, inhibition can be measured using square...

10.1039/d3ra00512g article EN cc-by-nc RSC Advances 2023-01-01

Cervical cancer (CxCa) is the most common in women and a prominent cause of mortality worldwide. The primary CxCa human papillomavirus (HPV). Radiation therapy chemotherapy have been used as standard treatments, but they undesirable side effects for patients. It was reported that gallic acid has antioxidant, antimicrobial, anticancer activities. Gold nanoparticles are currently being medicine biosensors drug delivery agents. This study aimed to develop agent using gold conjugated with acid....

10.7314/apjcp.2015.16.1.169 article EN cc-by Asian Pacific Journal of Cancer Prevention 2015-02-04

Silver nanoparticles (AgNPs) have a strong antimicrobial activity against variety of pathogenic bacteria. The killing mechanism AgNPs involves direct physical membrane destruction and subsequent molecular damage from both released Ag+. Burkholderia pseudomallei is the causative agent melioidosis, an endemic infectious disease primarily found in northern Australia Southeast Asia. B. intrinsically resistant to most common antibiotics. In this study, (10–20 nm) were investigated. MIC MBC for...

10.1371/journal.pone.0168098 article EN public-domain PLoS ONE 2016-12-15

In a recent study, we used chemical analysis to show that the Caesalpinia mimosoides aqueous extract, which contains high concentration of simple phenolics, has strong anti-influenza activity. We determined through molecular docking methods its potential target inhibitor is neuraminidase. Therefore, our study objectives were evaluate whether aqueous-ethanol extract (30% v/v) this plant species exhibits greater antiviral activity than extract. The C. hydroethanolic exhibited potent...

10.1038/s41598-025-87585-5 article EN cc-by-nc-nd Scientific Reports 2025-02-01

Houttuynia cordata Thunb. holds a longstanding reputation as traditional folk remedy in East Asia, where it has been employed to treat variety of inflammatory conditions, nephritis, hepatitis and cancer. Despite its extensive use, there exists paucity research examining efficacy managing thyroid disorders diabetes. Moreover, the bioactive components responsible for modulating molecular pathways remain elusive. Objectives: This aimed determine key ethanolic extract H. (HCEE) thyroid-modifying...

10.3390/nu17030594 article EN Nutrients 2025-02-06

This study investigates the immunomodulatory effects of various aqueous plant extracts on immune cells and cytokine production. In vitro, several extracts, including holy basil (Ocimum sanctum), patawali (Tinospora crispa), Indian borage (Plectranthus amboinicus L.), significantly increased CD3+ T-cell populations, while soap pod (Acacia concinna), garlic (Allium sativum neem (Azadirachta indica) also boosted CD45RA+ B-cells. vivo, had subtle spleen morphology Peyer's Patches, with milk bush...

10.1016/j.heliyon.2025.e42692 article EN cc-by-nc Heliyon 2025-02-01

Mitragyna speciosa (Ms), M. diversifolia (Md), hirsuta (Mh) and rotundifolia (Mr) were investigated for phytochemicals by GC-MS GC-FID, cytotoxicity genotoxicity testing MTT comet assay, biological activity examination through gene expression of human µ, δ, κ, nociceptin opioid receptors qRT-PCR. The substances mitragynine, 7-hydroxymitragynine, mitraphylline found in all studied species, and, first time, rhynchophylline was Mr, Md, Mh Mr. assays the ethanol hexane leaf extracts on PBMCs...

10.1038/s41598-025-89715-5 article EN cc-by Scientific Reports 2025-02-18

Bioconjugates in electrochemical biosensors can significantly enhance the detection process and sensitivity. In this study, we synthesized a monoclonal antibody-conjugated nanocomposite of graphene oxide Nafion (GO-Nf-mAb) for application an biosensor as novel all-in-one bioreceptor. The incorporation (Nf) improved stability, dispersity, antibody immobilization on GO surface, thereby increasing sensitivity biosensor. impact stability conjugation was thoroughly investigated compared to that...

10.1021/acsomega.5c00633 article EN cc-by-nc-nd ACS Omega 2025-03-28

This work describes the facile preparation of a disposable electrochemical biosensor for detection Hg(II) in water by modifying surface screen-printed carbon electrode (SPCE). The modification consists immobilization composite layer silver nanowires, hydroxymethyl propyl cellulose, chitosan, and urease (AgNWs/HPMC/CS/Urease). presence was confirmed scanning electron microscopy (SEM) its excellent conductivity, due chiefly to electrical properties enhanced sensitivity biosensor. Under optimum...

10.3390/bios11100351 article EN cc-by Biosensors 2021-09-23

Melioidosis is an infectious disease caused by Gram-negative bacillus bacteria Burkholderia pseudomallei. Due to the emerging resistance of B. pseudomallei antibiotics including ceftazidime (CAZ), development novel and alternative modes treatment has become urgent issue. Here, we demonstrated ability synergistically increase efficiency through their combination with silver nanoparticles (AgNPs). Combinations four conventional CAZ, imipenem (IMI), meropenem (MER), gentamicin sulfate (GENT)...

10.3390/antibiotics10070839 article EN cc-by Antibiotics 2021-07-10

The excessive use of antibiotics in both human and veterinary medicine has contributed to the development rapid spread drug resistance bacteria. Silver nanoparticles (AgNPs) have become a tool choice that can be used treat these resistant Several studies shown AgNPs antibacterial wound healing properties. In this study, we evaluated biological activity anisotropic develop an antimicrobial gel formulation for treating infections. We showed some (S2) effective against bacterial pathogens low...

10.3390/vetsci8090177 article EN cc-by Veterinary Sciences 2021-08-31

An uncomplicated and rapid colorimetric biosensor for the detection of highly toxic organophosphates (OPs) is developed, using pesticide dichlorvos as a representative OP.

10.1039/d2qm00186a article EN Materials Chemistry Frontiers 2022-01-01

Niosomes are employed for their improved physical properties and stability as a controlled delivery system. However, large-scale production different preparation methods affect properties. The microfluidic method represents novel approach to the of niosomes that enables precise control decreases time steps compared alternative methods. UVB protection anti-hyperpigmentation activities lycopene-loaded prepared by (MF) conventional thin-film hydration (THF) were compared. Extract powders from...

10.3390/ijms252111717 article EN International Journal of Molecular Sciences 2024-10-31
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