A5035679060- Spondyloarthritis Studies and Treatments
- Total Knee Arthroplasty Outcomes
- Advanced Neural Network Applications
- Orthopaedic implants and arthroplasty
- Osteoarthritis Treatment and Mechanisms
- Rheumatoid Arthritis Research and Therapies
- Inflammasome and immune disorders
- Video Surveillance and Tracking Methods
- Evacuation and Crowd Dynamics
- Psoriasis: Treatment and Pathogenesis
- Autonomous Vehicle Technology and Safety
- Hip disorders and treatments
- Bone Metabolism and Diseases
- MicroRNA in disease regulation
- Pomegranate: compositions and health benefits
- Calcium signaling and nucleotide metabolism
- Multimodal Machine Learning Applications
- Immune cells in cancer
- Lower Extremity Biomechanics and Pathologies
- Developmental Biology and Gene Regulation
- Finite Group Theory Research
- Circular RNAs in diseases
- RNA Research and Splicing
- Cold Atom Physics and Bose-Einstein Condensates
- Myofascial pain diagnosis and treatment
Changhai Hospital
2015-2024
Second Military Medical University
2015-2024
Shanghai East Hospital
2024
Shanghai Artificial Intelligence Laboratory
2023
ShangHai JiAi Genetics & IVF Institute
2023
Anhui Jianzhu University
2022
Xinxiang Medical University
2015
Zhejiang University
2003
Human driver can easily describe the complex traffic scene by visual system. Such an ability of precise perception is essential for driver's planning. To achieve this, a geometry-aware representation that quantizes physical 3D into structured grid map with semantic labels per cell, termed as Occupancy, would be desirable. Compared to form bounding box, key insight behind occupancy it could capture fine-grained details critical obstacles in scene, and thereby facilitate subsequent tasks....
Silibinin, a natural polyphenolic flavonoid, possesses anti-oxidant, anti-inflammation and anti-cancer properties. The present study was designed to investigate the effects of silibinin on rheumatoid arthritis (RA) pathogenesis-related cells collagen-induced (CIA) further explore potential underlying mechanisms. Our results showed that suppressed cell viability increased percentage apoptotic RA-fibroblast-like synoviocytes (FLS). Furthermore, production inflammatory cytokines in RA-FLS CIA...
Ankylosing spondylitis (AS) is a chronic autoimmune disease characterized by systemic inflammation and pathological osteogenesis. However, the genetic etiology of AS remains largely unknown. This study aimed to explore potential role coding noncoding genes in mechanism AS. Using microarray analyses, this comprehensively compared lncRNA, microRNA, mRNA profiles hip joint ligament tissues from patients with controls. A total 661 lncRNAs, 574 mRNAs, 22 microRNAs were differentially expressed...
Realistic and accurate simulations are crucial for developing quantum sensors such as cold atom gyroscopes, gravimeters, gradiometers in the field of interferometers (CAIs). However, current lack necessary specifications CAIs. In this study, we constructed a physical model CAIs designed detailed simulation program, including construction, input output parameter selection, program design, computational acceleration. The energy levels were rationally simplified approximated based on optical...
Large language models (LLMs) have opened up new possibilities for intelligent agents, endowing them with human-like thinking and cognitive abilities. In this work, we delve into the potential of large in autonomous driving (AD). We introduce DriveMLM, an LLM-based AD framework that can perform close-loop realistic simulators. To end, (1) bridge gap between decisions vehicle control commands by standardizing decision states according to off-the-shelf motion planning module. (2) employ a...
Ankylosing spondylitis (AS) is a chronic inflammatory disease characterized by sacroiliitis and spinal rigidity of the axial joints. The role oxidative stress increased proinflammatory cytokines well documented in AS pathogenesis. Punicalagin (2,3-hexahydroxydiphenoyl-gallagyl-D-glucose), an ellagitannin widely present pomegranates, found to exhibit potent anti-inflammatory, antiproliferative, antioxidative effects. study was undertaken investigate effects punicalagin rodent model AS.BALB/c...
This study aimed to identify the types and heterogeneity of cells within spinal enthesis investigate underlying mechanisms osteogenesis.
Autophagy is an important mechanism to maintain homeostasis in cells. It has been linked with ageing and many currently incurable diseases, including heart disease, cancer, myopathies, neurodegeneration, diabetes. research very for identifying better treatments. This study aimed explore the hotspots of autophagy published from different countries, organizations, authors.Between 1962 2018, articles about were identified Web Science database. The total annual number articles, citations, impact...
Objective: This study aims to investigate the influence of delirium following radical prostatectomy on cognitive function and health perception during recovery period. Methods: Data were collected from patients who underwent at our institution between May 2020 2022. Postoperative was assessed using Confusion Assessment Method for Intensive Care Unit (CAM-ICU), categorising into non-delirium groups. The Montreal Cognitive (MoCA) Brief Illness Perception Questionnaire (BIPQ) employed evaluate...
The Hospital for Special Surgery Hip Replacement Expectations Survey (HSS-THRES) and Knee (HSS-TKRES) are widely used tools developed to assess patients' preoperative expectations total hip knee arthroplasty. This study aimed translate adapt the HSS-THRES HSS-TKRES into Chinese versions (SC-THRES/TKRES) evaluate their psychometric properties in patients with osteoarthritis (OA) ankylosing spondylitis (AS).Patients scheduled (104 OA 51 AS) or replacements (101 OA) were recruited this study....
Ankylosing spondylitis (AS) is a chronic, progressive, and inflammatory disease that mainly affects the central axis joint. Although this has already been well documented studied, its pathogenesis still not understood. This study aimed to screen identify key candidate genes involved in progression of AS. For purpose, expression profiles GSE39340 GSE41038 were downloaded from Gene Expression Omnibus displayed form volcano plots heatmaps. Differentially expressed (DEGs) identified by Limma...
The Western Ontario Meniscal Evaluation Tool (WOMET) is a questionnaire designed to evaluate the health-related quality of life (HRQOL) patients with meniscal pathology. Our study aims culturally adapt and validate WOMET into Chinese version. We translated Chinese. Then, total 121 pathology were invited participate in this study. To assess test-retest reliability, version was completed twice at 7-day intervals by participants. construct validity assessed using Pearson's correlation...
Bone homeostasis is maintained by a dynamic balance between bone formation and resorption. The cellular activities of osteoblasts osteoclasts are the primary factors that maintain this balance. transcription factor Kaiso has been identified as regulator cell proliferation differentiation in various cells. However, research into its role currently lacking. In present study, animal experiments were conducted to investigate homeostasis. study was downregulated during osteoblast MC3T3‑E1 Gain‑...
With the re-popularity of metal-on-metal (MoM) bearing in recent years, cobalt toxicity has been a cause for concern total hip replacement surgery by both physicians and patients. MG-63 cell line was cultured vitro incubated with (II) chloride (CoCl2) and/or astaxanthin (ASX) 24 h. MTT assay conducted to evaluate viability after exposure ASX treatment. Fluorescence-activated sorting (FACS) analysis performed examine reactive oxygen species (ROS) level. Quantitative real-time polymerase chain...
Driving scenes are extremely diverse and complicated that it is impossible to collect all cases with human effort alone. While data augmentation an effective technique enrich the training data, existing methods for camera in autonomous driving applications confined 2D image plane, which may not optimally increase diversity 3D real-world scenarios. To this end, we propose a approach termed Drive-3DAug, aiming at augmenting on space. We first utilize Neural Radiance Field (NeRF) reconstruct...
Let G be a solvable block transitive automorphism group of 2−(v,5,1) design and suppose that is not flag transitive. We will prove if point imprimitive, then v=21, G⩽Z21:Z6; primitive, G⩽AΓL(1,v) v=pa, where p prime number with p≡21(mod40), an odd integer.
Abstract Purpose: Shoulder arthroscopy , as a minimally invasive surgical technique for patients who have shoulder injuries, has the advantages of short inpatient period and fast postoperative recovery. However, Patients experienced surgery common symptoms : pain . Which can delay rehabilitation influence result treatment Although there are many managements after surgery, adherence rate interventions remains low, adverse effects often occur. Electroacupuncture is traditional Chinese medicine...
Ankylosing spondylitis (AS) is a motor system immune disease with significant genetic characteristics, resulting in joint fusion, deformity, rigidity, seriously affecting the quality of life patients. Inflammatory bowel (IBD), characterized by intestinal mucosal damage and inflammatory changes, most common extra-articular manifestation AS. Due to limitations application therapeutic drugs, it urgent look for new mechanisms strategies effectively inhibit AS inflammation is. The content malic...
Objective Axial spondyloarthritis (axSpA) is a chronic rheumatic disease predominantly characterized by inflammation and progressive structural damage. Patients are often diagnosed very late, which delays the optimal treatment period. Early diagnosis of axSpA, especially non-radiographic axSpA (nr-axSpA), remains major challenge. This study aimed to investigate diagnostic value anti-Kaiso autoantibodies in their correlation with clinical indicators. Methods Two pooled serum samples (seven...