Samet Kara

ORCID: 0000-0003-0193-166X
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Research Areas
  • Alzheimer's disease research and treatments
  • Educational Methods and Analysis
  • Ovarian cancer diagnosis and treatment
  • Ion Transport and Channel Regulation
  • Biochemical Acid Research Studies
  • Values and Moral Education
  • MicroRNA in disease regulation
  • Neurogenesis and neuroplasticity mechanisms
  • Media Discourse and Social Analysis
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • RNA Interference and Gene Delivery
  • S100 Proteins and Annexins
  • Cerebrospinal fluid and hydrocephalus
  • Orthodontics and Dentofacial Orthopedics
  • Neuroscience and Neuropharmacology Research
  • Genomics, phytochemicals, and oxidative stress
  • Educator Training and Historical Pedagogy
  • Occupational exposure and asthma
  • Reproductive Biology and Fertility
  • Macrophage Migration Inhibitory Factor
  • Laser Applications in Dentistry and Medicine
  • Tryptophan and brain disorders
  • Biochemical effects in animals
  • Occupational and environmental lung diseases
  • Resilience and Mental Health

Cukurova University
2019-2025

Peripheral nerve injury (PNI) is a major health problem that results in loss of motor and sensory functions. In treatment PNI, various methods such as anastomosis, grafts, nonneural tissue conduits are applied. the present study, it was aimed to investigate effects Theranekron Alpha-lipoic acid (ALA) combined on healing experimental PNI by using histomorphometric, electron microscopic, immunohistochemical molecular biological methods. Sixty-two Wistar rats were divided into six groups;...

10.1080/01913123.2021.1923600 article EN Ultrastructural Pathology 2021-05-04

Functional disorders of the glymphatic system and Aquaporin-4 (AQP-4) channels take part in pathophysiology neurodegenerative disease. The aim this study was to describe distribution AQP-4 prefrontal cortex hippocampus a mouse model NMDA receptor blocking agent-induced schizophrenia-like behavior model. antagonist MK-801 used produce experimental schizophrenia injections were administered for eleven days Balb/c mice intraperitoneally. Beginning from sixth day injection, spatial learning...

10.1080/01913123.2021.2024633 article EN Ultrastructural Pathology 2022-01-02

Diabetes mellitus (DM), hiperglisemi ile karakterize kronik bir hastalıktır ve mikro- makrovasküler hastalıkları içeren komplikasyonları vardır. Nrf2 endojen inhibitörü Keap1, oksidatif stresle mücadele etmek için yaygın, evrimsel olarak korunmuş hücresel savunma mekanizması işlev görür. Sitoplazmik Keap1 tarafından tutulur bazal koşullarda proteazomal bozulmaya hedeflenir, stres durumunda Nrf2, Keap1'den ayrılır çekirdeğe taşınır, burada küçük Maf proteinlerinden biri heterodimer oluşturur....

10.17827/aktd.1435519 article TR Arşiv Kaynak Tarama Dergisi 2024-03-26

The use of chemotherapeutic agents during childhood, adolescence, and early adulthood has a detrimental effect on ovarian functions, leading to decrease in reserves, thus adversely affecting fertility. Alkylating are one the most frequently used groups chemotherapeutics this age group. An important effective drug, procarbazine is treat brain tumors Hodgkin lymphoma children, adolescents, young adults. This agent also an indispensable component combination-type chemotherapy. Procarbazine...

10.5114/aoms/184349 article EN cc-by-nc-sa Archives of Medical Science 2024-12-13

Ovarian torsion is twisting of the ovary around ligaments that support it. It a rare, but an important gynecological emergency. Detorsion surgically preferred in patients to preserve fertility. detorsion causes tissue damage response excessive reactive oxygen species and accumulation activated neutrophils. In this review, antioxidant anti-inflammatory agents have been investigated literature prevent ovarian injury due oxidative stress are summarised.

10.17827/aktd.1604053 article EN Arşiv Kaynak Tarama Dergisi 2024-12-27

The role of exercise in the treatment and prevention neurodegenerative diseases continues to remain unclear despite studies. In our study, protective effect treadmill on molecular pathways cognitive behaviors was investigated AD model induced by scopolamine.For that purpose, male Balb/cmice which separated from their mothers day 21 were subjected for 12 weeks. last 4 weeks exercise, scopolamine injection (2mg/kg,once a day) administered intraperitoneally mice. Following emotional evaluated...

10.2139/ssrn.4200911 article EN SSRN Electronic Journal 2022-01-01

Dörtgen şeklinde kalın bir kas olan masseter kasının en temel görevi mandibula’yı maxilla’ya karşı eleve etmek, dişlerin ısırma ve çiğneme işlevlerini gerçekleştirmek suretiyle çeneyi kapatmaktır. Lateral hareketlerde mandibula protraksiyonunda az da olsa görev alan kası, esasen yüz estetiğinde oldukça önem arz eden dört kasından biridir. Aralık 2021’de Mezey ark.ları tarafından yayınlanan makalede, anatomik olarak, kasına ait derin farklı üçüncü tabakanın os temporale processus zygomaticus...

10.17827/aktd.1332003 article TR cc-by-nc-nd Arşiv Kaynak Tarama Dergisi 2023-09-27

10.47845/turkishstudies.43873 article TR Turkish Studies - Language and Literature 2020-01-01

Amaç: Bu çalışmada, glioblastoma hücre hattında (U87) siklopamin ve temozolomid (TMZ) tedavisinin ayrı kombine olarak uygulanmasından sonra miR-20a ekspresyonunun araştırılması bu miRNA’nın tedavisindeki etkinliğinin değerlendirilmesi amaçlanmıştır. Gereç Yöntem: U87 MG, tedaviden önce 35 mm'lik kültür kabı üzerine yerleştirildi çoğaltıldı. Çalışma kapsamında 7 grup oluşturuldu: Grup 1: Kontrol grubu, 2: Sham grubu (Dimetil sülfoksit), 3: 2 Gün TMZ, 4: 5 5: 3 saat siklopamin, 6: TMZ + 7:...

10.17826/cumj.996520 article TR Çukurova medical journal (Online)/Çukurova medical journal 2021-09-20
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