A5101501546- Reproductive Biology and Fertility
- Birth, Development, and Health
- Animal Genetics and Reproduction
- Pain Mechanisms and Treatments
- Thermoregulation and physiological responses
- CRISPR and Genetic Engineering
- Climate Change Policy and Economics
- Plant tissue culture and regeneration
- Pluripotent Stem Cells Research
- Sports Performance and Training
- Transgenic Plants and Applications
- Acupuncture Treatment Research Studies
- Redox biology and oxidative stress
- Neuropeptides and Animal Physiology
- Prenatal Screening and Diagnostics
- Phytoestrogen effects and research
- Infrared Thermography in Medicine
- Biopolymer Synthesis and Applications
- Genetically Modified Organisms Research
- Olfactory and Sensory Function Studies
- Growth Hormone and Insulin-like Growth Factors
- Phytochemical and Pharmacological Studies
- Frailty in Older Adults
- Plant Disease Resistance and Genetics
- School Health and Nursing Education
Ningxia Medical University
2025
Shanghai Jiao Tong University
2023-2024
Shanghai First People's Hospital
2021-2024
Xi'an Polytechnic University
2017-2024
Center for Life Sciences
2022-2023
Tsinghua University
2021-2023
Beijing University of Agriculture
2021-2022
Research Institute of Forestry
2013
Chinese Academy of Forestry
2013
Nanjing Agricultural University
2011
Translational regulation plays a critical role during the oocyte-to-embryo transition (OET) and zygotic genome activation (ZGA). Here, we integrated ultra-low-input ribosome profiling (Ribo-lite) with messenger RNA sequencing to co-profile translatome transcriptome in human oocytes early embryos. Comparison mouse counterparts identified widespread differentially translated gene functioning epigenetic reprogramming, transposon defense, small biogenesis, part driven by species-specific...
Evolutionary analyses reveal conservation and divergence of epigenetic transition during early development across mammals.
Abstract Zygotic genome activation (ZGA) marks the beginning of embryonic program for a totipotent embryo, which gives rise to inner cell mass (ICM) where pluripotent epiblast arises, and extraembryonic trophectoderm. However, how ZGA is connected first lineage segregation in mammalian embryos remains elusive. Here, we investigated role nuclear receptor (NR) transcription factors (TFs), whose motifs are highly enriched accessible from 2-cell (2C) 8-cell (8C) stages mouse embryos. We found...
Abstract Background Neuropathic pain is chronic and has few effective control strategies. Studies have demonstrated that microRNAs functions in neuropathic pain. However, no study been conducted to demonstrate the role mechanism of microRNA (miR)-31-5p Accordingly, this sought determine pathological miR-31-5p constriction injury (CCI) -induced mouse models. Methods We used CCI surgery establish model. Behavioral tests were performed evaluate sensitivity mice. Expressions inflammatory...
This paper investigated principal parameters affecting individual differences of thermal preference. 36 male college students were selected from three preference groups by a questionnaire, including 10 cool (Gcp), 17 neutral (Gnp), and 9 warm (Gwp). Subsequently, their preferences further examined human trial in climate chamber. Once significant found between groups, subjects' 57 parameters, body geometry, composition, cardio-pulmonary capacity, physical fitness, measured. Compared to Gwp,...
With the advancement of generative models, synthesis different sensory elements such as music, visuals, and speech has achieved significant realism. However, approach to generate multi-sensory outputs not been fully explored, limiting application on high-value scenarios directing a film. Developing movie director agent faces two major challenges: (1) Lack parallelism online scheduling with production steps: In films, there are complex dependencies between elements, time for each element...
Human body can operate physiological thermoregulation system when it is exposed to cold or hot environment. Whether do the same work a local part of stimulated by different temperatures? The objective this paper prove it. Twelve subjects are recruited participate in experiment. After stabilizing comfort environment, their palms pouch 39, 36, 33, 30, and 27?C. Subject?s skin temperature, heart rate, heat flux skin, thermal sensation recorded. results indicate that suffering from harsh whole...
Neuropathic pain (NP) is a chronic and intractable disease that widely present in the general population. It causes painful behavior even mood changes such as anxiety depression by altering metabolism of substances. However, there have been limited metabolomics studies conducted relation to neuropathic pain. Therefore, this study, effects NP on metabolites serum dorsal root ganglion (DRG) were investigated using non-targeted approach detected gas chromatography-mass spectrometry (GC-MS)...