A5036651755- Genetic diversity and population structure
- Evolution and Genetic Dynamics
- Genomics and Phylogenetic Studies
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Livestock and Poultry Management
- Chromosomal and Genetic Variations
- Cephalopods and Marine Biology
- Genetic Mapping and Diversity in Plants and Animals
- Genetic and phenotypic traits in livestock
- Neuroendocrine regulation and behavior
- RNA Research and Splicing
- RNA and protein synthesis mechanisms
- CRISPR and Genetic Engineering
- Bioinformatics and Genomic Networks
- Invertebrate Taxonomy and Ecology
- Silk-based biomaterials and applications
- Primate Behavior and Ecology
- Biomedical Text Mining and Ontologies
- Fish Ecology and Management Studies
- Cancer Genomics and Diagnostics
- Neurobiology and Insect Physiology Research
- Animal Behavior and Reproduction
- Identification and Quantification in Food
- Animal Genetics and Reproduction
University of Vienna
2023-2024
Cardiff University
2024
University of Sheffield
2019-2022
Males and females of the same species share majority their genomes, yet they are frequently exposed to conflicting selection pressures. Gene regulation is widely assumed resolve these sex-specific pressures, although there has been considerable focus on elucidating role gene expression level in adaptation, other regulatory mechanisms have overlooked. Alternative splicing enables different transcripts be generated from gene, meaning that exons which beneficial effects can theory retained...
Intralocus sexual conflict, where an allele benefits one sex at the expense of other, has important role in shaping genetic diversity populations through balancing selection. However, potential for mating systems to exert selection conflict on genome remains unclear. Furthermore, nature and resolution across been hotly debated. To address this, we analysed de novo transcriptomes from six avian species, chosen reflect full range dimorphism systems. Our analyses combine expression population...
Abstract Coleoid cephalopods possess numerous complex, species-specific morphological and behavioural adaptations, e.g., a uniquely structured nervous system that is the largest among invertebrates. The Hawaiian bobtail squid ( Euprymna scolopes ) one of most established cephalopod species. With its recent publication chromosomal-scale genome assembly regulatory genomic data, it also emerges as key model for gene regulation evolution. However, latest has been lacking native set. Our...
Few animal groups can claim the level of wonder that cephalopods instill in minds researchers and general public. Much cephalopod biology, however, remains unexplored: largest invertebrate brain, difficult husbandry conditions, complex (meta-)genomes, among many other things, have hindered progress addressing key questions. However, recent technological advancements sequencing, imaging, genetic manipulation opened new avenues for exploring biology these extraordinary animals. The molecular...
Abstract The sex chromosomes often follow unusual evolutionary trajectories. In particular, the sex-limited frequently exhibit a small but gene content in numerous species, where many genes have undergone massive amplification. reasons for this remain elusive with number of recent studies implicating meiotic drive, sperm competition, genetic drift, and conversion expansion families. However, our understanding is primarily based on Y chromosome as few systematically tested copy variation W...
Abstract The Sister Islands rock iguana ( Cyclura nubila caymanensis ) is critically endangered and endemic to the Caribbean islands Little Cayman Brac. Brac population indeed entire species under threat from habitat destruction, invasive species, anthropogenic impacts on island. We assessed genetic diversity, estimated effective sizes, tested for differentiation of populations between these two inform potential future translocation should this be needed population. Two mitochondrial DNA...
The missing heritability problem, defined as the failure of genetic variants to explain variance in phenotypes, has been an unsolved issue genetics for past two decades. A potential solution this problem stems from idea that single nucleotide polymorphisms and copy-number variants, most commonly studied forms genomic diversity, do not represent totality information is transferred one generation next. In perspective, we offer a glimpse into hidden dimensions diversity: frequently neglected...
A substantial amount of phenotypic diversity results from changes in gene regulation.Understanding how regulatory evolves is therefore a key priority identifying mechanisms adaptive change.However, contrast to powerful models sequence evolution, we lack consensus model evolution.Furthermore, recent work has shown that many the comparative approaches used study regulation are subject biases can lead false signatures selection.In this review, first outline main for describing evolution and...