A5091102186- Gut microbiota and health
- Reproductive tract infections research
- Pelvic floor disorders treatments
- Urinary Tract Infections Management
- Electrospun Nanofibers in Biomedical Applications
- Nanocomposite Films for Food Packaging
- Advanced Sensor and Energy Harvesting Materials
- Molecular Biology Techniques and Applications
- Conducting polymers and applications
- Bariatric Surgery and Outcomes
- Cervical Cancer and HPV Research
- Urinary Bladder and Prostate Research
- Genomics and Phylogenetic Studies
- Reproductive System and Pregnancy
- Silk-based biomaterials and applications
- Electrodeposition and Electroless Coatings
- Dental materials and restorations
- Surface Modification and Superhydrophobicity
- Nanomaterials for catalytic reactions
- Salivary Gland Disorders and Functions
- Dielectric materials and actuators
- Bone Tissue Engineering Materials
- Gestational Diabetes Research and Management
- Obesity and Health Practices
- Clostridium difficile and Clostridium perfringens research
BGI Group (China)
2017-2024
BGI Research
2017-2024
Botswana Geoscience Institute
2024
University of Copenhagen
2024
China National GeneBank
2017-2020
Hefei University of Technology
2015-2017
University of Chinese Academy of Sciences
2017
Hefei University
2016
The human uterus is traditionally believed to be sterile, while the vaginal microbiota plays an important role in fending off pathogens. Emerging evidence demonstrates presence of bacteria beyond vagina. However, a microbiome-wide metagenomic analysis characterizing diverse microbial communities has been lacking.
The number of large-scale studies on the gut microbiota in human cohorts is rapidly increasing. However, few and expensive options for storage fecal samples at room temperature have been an obstacle metagenomic development clinical/commercial personal sequencing. In this study, we systematically tested a novel N-octylpyridinium bromide-based sample preservation method compared it with other currently used methods. We found that enabled bacterial composition transported stored up to least 14...
The proanthocyanidins encapsulated in zein (zein-PA) fibers was via electrospinning technique. kinetics and antioxidant capacity of PA from investigated by cyclic voltammetry. Circular dichroism used to investigate the secondary structure change its influence on shape fibers. addition caused a significant increase viscosity made wider. These hydrogen bonds between molecules would favor α-helix decrease β-folds solutions, leading round-shaped tendency enhancing thermal properties slightly....
The vagina contains at least a billion microbial cells, dominated by lactobacilli. Here we perform metagenomic shotgun sequencing on cervical and fecal samples from cohort of 516 Chinese women reproductive age, as well cervical, fecal, salivary second 632 women. Factors such pregnancyhistory, delivery history, cesarean section, breastfeeding were all more important than menstrual cycle in shaping the microbiome, information would be necessary before trying to interpret differences between...
Human gut dysbiosis is associated with type 2 diabetes mellitus (T2DM); however, the microbiome in pregnant women pregestational (PGDM) remains unexplored. We investigated alterations microbiota composition or without PGDM. The was examined using 16S rRNA sequencing data of 234 maternal fecal samples that were collected during first (T1), second (T2), and third (T3) trimesters. PGDM group presented a reduction number bacteria taxonomies as pregnancies progressed. Linear discriminant analyses...
Abstract The vaginal microbiota is essential for women’s health, yet its genomic diversity and host relevance remains incompletely characterized. Here we established a Chinese cohort with 10,281 metagenomes. We developed an extensive catalog of microbial genomes (VMG) by integrating 6,979 in-house metagenomes 1,817 publicly available over 1,000 bacterial isolates. This comprised 46,906 from 913 prokaryotic species 3,763 viral populations, 23.8% prokaryotes 75.1% viruses being not found in...
ABSTRACT Tetracycline hydrochloride loaded poly (vinyl alcohol)/chitosan/ZrO 2 (Tet‐PVA/CS/ZrO ) hybrid nanofibers were fabricated via electrospinning technique. The representative weight ratio of PVA/CS at 3 : 1 was chosen to fabricate drug carrier PVA/CS/ZrO nanofibers. showed a decrease in average diameter with the increase ZrO content given conditions, and uneven interspersed spindle‐shape beads 60 wt % above. networks linked by hydrogen Zr–O–C bonds among PVA, CS, units resulted...
Human urine is traditionally considered to be sterile, and whether the harbours distinct microbial communities has been a matter of debate. Potential links between female reproductive tract currently not clear. Here, we collected samples from 147 Chinese women age explored nature colonization by 16S rRNA gene amplicon sequencing, quantitative real-time PCR, live bacteria culture. To demonstrate utility this approach, intra-individual Spearman's correlation was used explore relationship...
The gut microbiome has been the center of attention for human commensal studies. vaginal is also densely populated with bacteria, viruses and fungi, presence microorganisms beyond cervix increasingly reported in non-infectious conditions 1–3 . Due to over 90% sequences female reproductive tract samples 3,4 , metagenomic information very limited. 16S rRNA gene amplicon sequencing studies have identified community types microbiota, observed its dynamic changes due menstrual cycles sexual...
We fabricated mesoporous hydroxylapatite/activated carbon bead-on-string nanofibers from electrospun by a hydrothermal method and evaluated their sorption towards Co(<sc>ii</sc>)<italic>via</italic>sorption kinetics isotherms.
This protocol is used to clarity the process of total DNA extration for human microbe samples.
Abstract The vaginal microbiota is presumably much simpler than the gut microbiome, and oral probiotics appear as a promising means to modulate its homeostasis in general population. Here, 60 women were followed for over year before, during after probiotic containing Lactobacillus rhamnosus GR-1 L. reuteri RC-14. Shotgun metagenomic data of 1334 samples from multiple body sites did not support colonization vagino-cervical yet microbiome was stable those dominated by Lactobacilli some...
Deal with the 16S rRNA amplicon sequencing reads, which sequenced by Ion PGMTM Sequencer 318TMChip v2 a read length of 400bp, and takes OTU table( measured abundance profile detected operational taxonomic units (OTUs)).
Abstract Human urine is traditionally considered to be sterile, and whether the harbours distinct microbial communities has been a matter of debate. The potential link between female reproductive tract currently not clear. Here we collected samples from 147 Chinese women age, explored nature colonization by 16S rRNA gene amplicon sequencing, real-time qPCR live bacteria culture. To demonstrate utility intra-individual Spearman’s correlation was used explore relationship multi-sites tract....