A5071625261- Analytical Chemistry and Chromatography
- Microfluidic and Capillary Electrophoresis Applications
- Microbial bioremediation and biosurfactants
- Enzyme-mediated dye degradation
- Analytical Methods in Pharmaceuticals
- Analytical chemistry methods development
- Toxic Organic Pollutants Impact
- Environmental Chemistry and Analysis
- Antibiotics Pharmacokinetics and Efficacy
- Fungal Biology and Applications
- Pesticide and Herbicide Environmental Studies
- Essential Oils and Antimicrobial Activity
- Lipid Membrane Structure and Behavior
- Plant biochemistry and biosynthesis
- RNA Interference and Gene Delivery
- Spectroscopy and Quantum Chemical Studies
- Field-Flow Fractionation Techniques
- Phytochemicals and Antioxidant Activities
- Edible Oils Quality and Analysis
- Environmental Toxicology and Ecotoxicology
- Parasites and Host Interactions
- Phytochemistry and biological activity of medicinal plants
- Fluoride Effects and Removal
- Silymarin and Mushroom Poisoning
- Biochemical and biochemical processes
National Research Council
2006-2025
Institute for Biological Systems
2019-2024
Istituto di Metodologie Chimiche
2008-2018
Vytautas Magnus University
2017
Kaunas University of Technology
2017
National Academies of Sciences, Engineering, and Medicine
2008
Sapienza University of Rome
1999-2005
The positive charge on liposome surface is known to promote the crossing of Blood brain barrier (BBB). However, when diastereomeric cationic gemini amphiphiles are among lipid membrane components, also stereochemistry may affect permeability vesicle across BBB.Liposomes featuring diasteromeric were formulated, characterized, and their interaction with cell culture models BBB investigated.Liposomes internalized in a monolayer microvascular endothelial cells derived from human induced...
Abstract Introduction and Objective Rumex sanguineus , a traditional medicinal plant of the Polygonaceae family, is gaining popularity as an edible resource. However, despite its historical nutritional significance, chemical composition remains poorly understood. To deepen understanding composition, in-depth analysis using non-targeted, mass spectrometry-based metabolomics was performed. Methods roots, stems leaves samples were analyzed by UHPLC-HRMS subsequently subjected to feature-based...
Investigation of the impact two approaches, chemical modification by lipophilization and liposomal encapsulation, on antioxidant antimicrobial properties hydroxytyrosol.
Abstract Background Perfluoroalkyl substances (PFASs) are emerging contaminants of increasing concern due to their presence in the environment, with potential impacts on ecosystems and human health. These considered “forever chemicals” recalcitrance degradation, accumulation living organisms can lead varying levels toxicity based compound species analysed. Furthermore, concerns have been raised about possible transfer PFASs humans through consumption edible parts food plants. In this regard,...
Antibiotic resistance due to bacterial biofilm formation is a major global health concern that makes the search for new therapeutic approaches an urgent need. In this context,, trans-resveratrol (RSV), polyphenolic natural substance, seems be good candidate preventing and eradicating biofilm-associated infections but its mechanism of action poorly understood. addition, RSV suffers from low bioavailability chemical instability in biological media make encapsulation delivery systems necessary....
Olive (Olea europea L.) is one of the oldest and most important fruit tree species cultivated in Mediterranean region. Various plant tissues, drupes, olive oil contain several phenolics (including verbascoside, although it present at a low level) that are well-known for their highly beneficial effects on human health. An vitro cell suspension culture (cultivar Cellina di Nardò, "CdN") was established, characterized its growth morphological features. Furthermore, vital relatively uniform...
For over two decades, a racemic mixture of oxamniquine (OXA) was administered to patients infected by Schistosoma mansoni, but whether one or both enantiomers exert antischistosomal activity unknown. Recently, ~30 kDa S. mansoni sulfotransferase (SmSULT) identified as the target OXA action.Here, we separate using chromatographic methods and assign their optical activities dextrorotary [(+)-OXA] levorotary [(-)-OXA]. Crystal structures parasite enzyme in complex with optically pure (+)-OXA...
A group of 36 fungal strains, belonging to the Lithuanian mycobiota, was collected and isolated from different locations, habitats, matrices, including creosote-treated wood in storage yards for crosstie wastes. The eight most perspective strains selected according preliminary assessment tolerance coal tar were subsequently identified combining taxonomical evaluation molecular techniques. species (five basidiomycetes three ascomycetes) presence various concentrations tar, four (Pleurotus...
A wide use of foaming agents as lubricants is required in mechanized tunneling. Their main component, the anionic surfactant sodium lauryl ether sulphate (SLES), can remain residual concentrations soil debris, influencing their potential reuse by-product. This study aimed at evaluating environmental fate and effects a product used for conditioning soils collected from real excavation sites, presence/absence an anti-clogging polymer, both containing SLES. Soil microcosm experiments were...
According to the innovative and sustainable perspective of circular economy model, Olea europaea leaves, a solid byproduct generated every year in large amounts by olive oil production chain, are considered valuable source bioactive compounds, such as polyphenols, with many potential applications. In particular, following study aimed valorize leaves order obtain products antibacterial activity. this study, leaf extracts, rich were prepared ultrasound-assisted extraction using green solvents,...