A5103121270- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
- Advanced battery technologies research
- Circular RNAs in diseases
- Electrocatalysts for Energy Conversion
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Frailty in Older Adults
- Colorectal Cancer Surgical Treatments
- CO2 Reduction Techniques and Catalysts
- Advanced Antenna and Metasurface Technologies
- Fuel Cells and Related Materials
- Electromagnetic wave absorption materials
- RNA modifications and cancer
- Nutrition and Health in Aging
- Ionic liquids properties and applications
- Ferroptosis and cancer prognosis
- Protein purification and stability
- Polymer Surface Interaction Studies
- Dielectric materials and actuators
- Mesenchymal stem cell research
- Gastric Cancer Management and Outcomes
- Muscle Physiology and Disorders
- Carbon dioxide utilization in catalysis
- Flame retardant materials and properties
- Neurogenetic and Muscular Disorders Research
Third Affiliated Hospital of Guangzhou Medical University
2014-2024
Guangzhou Medical University
2014-2024
Fujian Agriculture and Forestry University
2024
Shenzhen University
2023-2024
Eastern Hepatobiliary Surgery Hospital
2019-2023
Second Military Medical University
2019-2023
Key Laboratory of Guangdong Province
2023
Tianjin University
2012-2020
University of South China
2016
Anhui Medical University
2016
The tandem application of CO2 electrolysis with syngas fermentation holds promise for achieving heightened production rates and improved product quality. However, the significant impact composition on mixed culture-based microbial chain elongation remains unclear. Additionally, effective methods generating an adjustable from acidic are currently lacking. This study successfully demonstrated medium-chain fatty acids through fermentation. CO could serve as sole energy source or electron donor...
One challenge remaining in the development of Ir-based electrocatalyst is activity-stability paradox during acidic oxygen evolution reaction (OER), especially for surface reconstructed IrOx catalyst with high efficiency. To address this, a phase selective constructed by forming bridged W-O moiety NiIrOx electrocatalyst. Through an electrochemical dealloying process, nano-porous structure surface-hydroxylated rutile NiWIrOx engineered via Ni as sacrificial element. Despite low Ir content,...
Mesenchymal stem cells (MSCs) exert a tumor-promoting effect in variety of human cancers. This study was designed to identify the molecular mechanisms related MSCs colorectal cancer. In vitro analysis cancer cell lines cultured MSC conditioned media (MSC-CM) showed that MSC-CM significantly promoted progression by enhancing proliferation, migration and colony formation. The tumorigenic attributed altered expression cycle regulatory proteins inhibition apoptosis. Furthermore, induced high...
Abstract Background Frailty is considered a characteristic manifestation of physiological decline in multiple organ systems, which significantly increases the vulnerability elderly individuals with colorectal cancer (CRC) and associated poor prognosis. While studies have demonstrated that 11-factor Modified Index (mFI-11) can effectively predict adverse outcomes following radical resection CRC, there lack research on applicability 5-factor (mFI-5) within this patient population. Methods In...
This study presents a straightforward chemical approach to induce cationic surface defects on SrCoO3-δ (SCO) perovskites by selectively etching a-site Sr elements the surface. The modified SCO-30 catalyst from this method exhibits an optimized thickness of cobalt-rich amorphous layer enriched with oxygen vacancies. modification enhances trifunctional catalytic activity for evolution reaction (OER), reduction (ORR), and hydrogen (HER) in alkaline electrolyte. Importantly, perovskite's...
The demand for converting CO2 into fuels or chemicals is on the rise to achieve a carbon-efficient circular economy. Biohybrid electrolysis shows potential increasing production rates and diversifying product spectra by combining electrocatalysts microbial catalysts. However, it important note that utilizing shared catholyte biohybrid has not demonstrated significant performance improvements date. In this study, we developed system solid electrolyte operating in an external mode. produced...
Efficient and robust electrocatalysts applicable to acid water electrolysis is crucial for the development of high-performance PEM (proton exchange membrane) electrolyzer. Herein, a customized structural reconstruction strategy developed to...
<title>Abstract</title> <bold>Background</bold> Spinal muscular atrophy (SMA) is a severe neuromuscular disorder caused by the loss of motor neurons in spinal cord. Our team has initiated clinical trials using adeno-associated virus serotype 9 (AAV9) vectors carrying codon-optimized SMN1 (coSMN1) gene, delivered via intrathecal (IT) injection. Here, we present preclinical research that laid groundwork for these trials, offering comprehensive data on efficacy and safety AAV9-coSMN1 both...
Abstract Background Spinal muscular atrophy (SMA) is a severe neuromuscular disorder caused by the loss of motor neurons in spinal cord. Our team has initiated clinical trials using adeno-associated virus serotype 9 (AAV9) vectors carrying codon-optimized human SMN1 (coSMN1) gene, delivered via intrathecal (IT) injection. Here, we present preclinical research that laid groundwork for these trials, offering comprehensive data on efficacy and safety AAV9-coSMN1 both murine models non-human...
Abstract A novel and effective protocol for the preparation of superparamagnetic immunomicrospheres has been developed. First, micro‐size magnetic poly (methacrylate‐divinylbenzene) (PMA‐DVB) spheres were prepared by a modified suspension polymerization method. The oleic acid coated magnetite (Fe 3 O 4 ) nanoparticles made coprecipitation mixed with monomers MA, DVB, initiator benzoyl peroxide (BPO) to form oil in water emulsion droplets presence (vinyl alcohol) (PVA‐1788) as stabilizer....
MicroRNAs (miRNAs), a class of small non-coding RNAs, can induce mRNA degradation or repress translation by binding to the 3'-untranslated region (UTR) its target mRNA. Recently, some specific miRNAs, e.g. miR-93, have been found be involved in pathological processes targeting oncogenes tumor suppressors glioma. However, regulatory mechanism miR-93 biological behaviors and chemoresistance glioma cells remains unclear. In present study, situ hybridization real-time RT-PCR data indicated that...
Aberrant expression of microRNAs (miRNAs) has been implicated in human cancer, including colorectal cancer (CRC). Such dysregulated miRNAs may have potential as diagnostic markers or therapeutic targets. However, the nature an association between these and clinical stages CRC is still not clear. To this end, we performed a miRNA profiling 1547 distinct using 31 samples tumor paired normal mucosa obtained from patients. Based on statistical analyses data, identified 569 that were...
Colorectal cancer represents a lethal disease that has raised concern and attracted significant attention. Adenocarcinoma is the most common type of colorectal (CRC). MicroRNAs are thought to be potential biomarkers CRC. Many researchers have focused on expression pattern miRNAs in However, previous studies did not pay particular attention effects degree differentiation with respect miRNA profile. First, this study compared level 1547 by qRT-PCR adenocarcinoma tissues paired normal tissues....
Introduction: Colorectal cancer (CRC) is one of the most common illnesses that seriously threatens human health; many papers have reported microRNAs (miRNAs) are promising biomarkers for detection. However, miRNAs not been used in clinical practice even though they superior to currently screening tools, such as fecal occult blood test (FOBT) and carcinoembryonic antigen (CEA) measurement. Methods: In this study, we focused on usefulness a panel combination with FOBT CEA measurement, general...