A5000769091- Cerebral Palsy and Movement Disorders
- Botulinum Toxin and Related Neurological Disorders
- Neonatal and fetal brain pathology
- Neurological disorders and treatments
- Infant Development and Preterm Care
- Family and Disability Support Research
- Stroke Rehabilitation and Recovery
- Parkinson's Disease Mechanisms and Treatments
- Advanced Neuroimaging Techniques and Applications
- Neurogenetic and Muscular Disorders Research
- Genetics and Neurodevelopmental Disorders
- Genomics and Rare Diseases
- Down syndrome and intellectual disability research
- Autoimmune Neurological Disorders and Treatments
- Balance, Gait, and Falls Prevention
- Assistive Technology in Communication and Mobility
- Traumatic Brain Injury Research
- Migraine and Headache Studies
- Neuroscience and Neural Engineering
- Autism Spectrum Disorder Research
- Delphi Technique in Research
- Pain Management and Placebo Effect
- Pain Mechanisms and Treatments
- Trigeminal Neuralgia and Treatments
- Pediatric Pain Management Techniques
Washington University in St. Louis
2012-2025
St. Louis Children's Hospital
2014-2024
Saint Louis University
2020-2024
Cerebral Palsy Alliance
2024
The University of Sydney
2024
Cerebral Palsy Research Network
2022-2024
Children's Healthcare of Atlanta
2024
University of Virginia
2024
Emory University
2024
Providence Health & Services
2024
Object The pedunculopontine nucleus (PPN) region of the brainstem has become a new stimulation target for treatment gait freezing, akinesia, and postural instability in advanced Parkinson disease (PD). Because PD locomotor symptoms are probably caused by excessive γ-aminobutyric acidergic inhibition PPN, low-frequency PPN may overcome this improve symptoms. However, anatomical connections humans not known any detail. Methods Diffusion weighted magnetic resonance (MR) images were acquired at...
We have established that physicians, including neurologists, variably diagnose cerebral palsy (CP) when using the most recent CP definition from 2006. also know child neurologists and neurodevelopmentalists view themselves to be optimally suited based on their training backgrounds. Therefore, reduce variability in diagnosis, our objective was elucidate uncertainties may regarding practical application of 2006 definition.
BACKGROUND: Cerebral palsy (CP) is the most common childhood motor disability. The emergence of genetic CP etiologies, variable inclusion hypotonic in international registries, and involvement different medical disciplines diagnosis can promote diagnostic variability. This variability could adversely affect patients’ understanding their symptoms access to care. Therefore, we sought determine presence extent practice diagnosis. METHODS: We surveyed physicians United States Canada interested...
Dystonia in cerebral palsy (DCP) is a common, debilitating, but understudied condition. The CP community (people with and caregivers) uniquely equipped to help determine the research questions that best address their needs. We developed community-driven DCP agenda using well-established James Lind Alliance methodology. members, researchers, clinicians were recruited through multiple advocacy, research, professional organizations. To ensure shared baseline knowledge, participants watched...
Abstract Aim To determine the movement features governing expert assessment of gait dystonia severity in individuals with cerebral palsy (CP). Method In this prospective cohort study, three disorder neurologists graded lower extremity videos CP using a 10‐point Likert‐like scale. Using conventional content analysis, we determined experts cited when grading severity. Then, open‐source pose estimation techniques, variable analogs these expert‐cited correlating their assessments Results Experts...
Hemiplegic cerebral palsy affects 1 in every 1,100 children, making it the most common pediatric motor disability. Constraint-Induced Movement Therapy (CIMT) is an evidence-based intervention that significantly improves upper extremity function when implemented with high fidelity. Despite its effectiveness, CIMT's intensive nature-requiring daily therapy for up to twenty days-limits availability. This study examined caregivers' perspectives on implementing and adapting home-based CIMT...
Dystonia is a common, debilitating, and often treatment-refractory motor symptom of cerebral palsy (CP), affecting 70%-80% this population based on research assessments. However, routine clinical evaluation for dystonia in CP has failed to match these expected numbers. Addressing diagnostic gap medical imperative because the presence rules or out certain treatments symptoms CP. Therefore, our objective was optimize rates screening improve diagnosis. Using quality improvement (QI)...
To determine how caregivers describe dystonia in people with cerebral palsy (CP).
Gender disparities have been demonstrated across several medical specialties, including neurology. Although women comprised most of the child neurology trainees since 2007, it is not apparent whether this demographic shift reflected in Child Neurology Society (CNS) awards and leadership. This study aimed to evaluate differences gender representation among leadership positions award recipients within CNS. The primary outcome measure was total number board director (BOD) or given by each year.
In-person resident didactics are traditionally limited to the faculty within a single institution. Tele-education efforts have been implemented in neurology various degrees historically, but coronavirus disease 2019 (COVID-19) pandemic has necessitated broad and immediate overhaul didactic training. To respond need for didactics, we created rapid onset, volunteer tele-education series publicized on online forums American Academy of Neurology A.B. Baker Section via Synapse Women Neurologists...
The authors examined how the COVID-19 pandemic affected behavioral health of people with intellectual and developmental disabilities (IDD).A modified version Coronavirus Health Impact Survey-Adapted for Autism Related Neurodevelopmental Conditions was sent to authors' clinical networks IDD-affiliated organizations from March June 2021.In total, 437 IDD or their caregivers responded survey. Diagnoses included disability (51%) autism spectrum disorder (48%). More than half (52%) respondents...
Abstract Objective To determine the rates of clinical under‐documentation leg dystonia in people with cerebral palsy (CP). Methods In this prospective cohort study, we identified independently ambulatory age 10–20 years CP‐associated spasticity seen a tertiary care CP center between 1/1/20 and 11/4/21. Three pediatric movement disorders specialists assessed gait videos from these visits for using Global Dystonia Rating Scale. We compared gold standard expert consensus assessment each patient...
Deep brain stimulation (DBS) of the pedunculopontine nucleus (PPN) has recently been shown to effectively ameliorate medically intractable axial symptoms Parkinson's disease (PD). The effects DBS are not limited targeted structure, but will affect distributed anatomical networks which target structure belongs. Therefore, understanding connections PPN help elucidate treatment effects. Furthermore, establishing topography cortical and sub-cortical in human could aid accurate targeting critical...
Background Early spasticity and dystonia identification in cerebral palsy is critical for guiding diagnostic workup prompting targeted treatment early when it most efficacious. However, differentiating from difficult young children with palsy. Methods We sought to determine underidentification rates at high risk (following neonatal hypoxic-ischemic encephalopathy) by assessing how often child neurologists identified hypertonia alone versus specifying the type as and/or age 5 years. Results...