Michaela Mihulová
A5005079276- RNA modifications and cancer
- Craniofacial Disorders and Treatments
- Neurogenetic and Muscular Disorders Research
- Orthodontics and Dentofacial Orthopedics
- Child Nutrition and Feeding Issues
- Genomics and Rare Diseases
- Facial Trauma and Fracture Management
- Autism Spectrum Disorder Research
- Genetics and Neurodevelopmental Disorders
University Hospital in Motol
2024
Charles University
2023-2024
Abstract The Human Phenotype Ontology (HPO) is a widely used resource that comprehensively organizes and defines the phenotypic features of human disease, enabling computational inference supporting genomic analyses through semantic similarity machine learning algorithms. HPO has widespread applications in clinical diagnostics translational research, including diagnostics, gene-disease discovery, cohort analytics. In recent years, groups around world have developed translations from English...
Cluster analyzes of facial models autistic patients aim to clarify whether it is possible diagnose autism on the basis features and further stratify spectrum disorder. We performed a cluster analysis sets 3D scans ASD (116) controls (157) using Euclidean geodesic distances in order recapitulate published results Czech population. In presented work, we show that major factor determining clustering structure consequently also correlation resulting clusters with severity degree body mass index...
Abstract Aim To utilize three‐dimensional (3D) geometric morphometry for visualization of the level facial asymmetry in patients with oculo‐auriculo‐vertebral spectrum (OAVS). Materials and Methods Three‐dimensional scans 25 Czech OAVS were processed. The divided into subgroups according to Pruzansky classification. For 13 them, second 3D obtained. processed using morphometry. Soft tissue sagittal plane its changes two time spots visualized colour‐coded maps a thermometre‐like scale. Results...