A5044259942- Insect-Plant Interactions and Control
- Insect Resistance and Genetics
- Insect and Pesticide Research
- Insect Pest Control Strategies
- Insect symbiosis and bacterial influences
- Plant Virus Research Studies
- GDF15 and Related Biomarkers
- Mycotoxins in Agriculture and Food
- Macrophage Migration Inhibitory Factor
- Entomopathogenic Microorganisms in Pest Control
- Insect Pheromone Research and Control
- Immune Response and Inflammation
- Nematode management and characterization studies
- Environmental DNA in Biodiversity Studies
- Nutrition and Health in Aging
- Helicobacter pylori-related gastroenterology studies
- Plant and animal studies
- Agriculture, Soil, Plant Science
- Identification and Quantification in Food
- Ecology and Conservation Studies
- Food Quality and Safety Studies
- NF-κB Signaling Pathways
- Korean Urban and Social Studies
- Engineering Applied Research
- Endoplasmic Reticulum Stress and Disease
Kangwon National University
2020-2025
Pusan National University
2014-2025
Korea Maritime Institute
2025
Institute of Crop Science
2008-2020
Rural Development Administration
2008-2020
Max Planck Institute for Chemical Ecology
2016-2018
National Institute of Agricultural Science and Technology
2017-2018
Institute for Basic Science
2015-2016
Chungbuk National University
2013
Soongsil University
2005
The fall armyworm (FAW) Spodoptera frugiperda is thought to have undergone a rapid 'west-to-east' spread since 2016 when it was first identified in western Africa. Between 2018 and 2020, recorded from South Asia (SA), Southeast (SEA), East (EA), Pacific/Australia (PA). Population genomic analyses enabled the understanding of pathways, population sources, gene flow this notorious agricultural pest species. Using neutral single nucleotide polymorphic (SNP) DNA markers, we detected genome...
Endoplasmic reticulum (ER) stress is a causative factor of inflammatory bowel diseases. ER mediators, including CCAAT enhancer-binding protein (C/EBP) homologous (CHOP), are elevated in intestinal epithelia from patients with The present study arose the question how chemical and CHOP were associated nuclear factor-κB (NF-κB)-mediated epithelial response. In human cell culture model, stresses induced proinflammatory cytokine interleukin-8 (IL-8) expression translocation protein. was...
Although mucoactive proteins, such as epidermal growth factor (EGF), could improve clinical outcomes of intestinal ulcerative diseases, their gastrointestinal application is limited because proteolytic digestion or concerns about tumor promotion. In the present study, ATP-binding cassette (ABC) transporter-linked secretion human EGF from probiotic Escherichia coli (EGF-EcN) was created to promote beneficial actions receptor, which notably attenuated in patients with injuries. Preventive and...
Abstract BACKGROUND The fall armyworm, Spodoptera frugiperda is a native species of the Americas. First detected in western and central Africa early 2016, it has become one most serious invasive lepidopteran pests many African Asian countries. S. spread very quickly; however, there are no molecular‐based, simple accurate diagnostic tools for identification this field. Methods to identify urgently needed because farmers agricultural managers have prior experience with pest. RESULTS Based on...
Genome-wide long non-coding RNAs (lncRNAs) in low, moderate, and high pyrethroid insecticide-resistant -susceptible strains of Helicoverpa armigera were identified this study. Using 45 illumina-based RNA-sequencing datasets, 8394 lncRNAs identified. In addition, a sublethal dose deltamethrin was administered to Korean-resistant strain (Kor-T). The average length approximately 531 bp, the expression ratio 28% total RNA. divided into six categories—intronic, intergenic, sense, antisense,...
Deoxynivalenol (DON), a prevalent mycotoxin produced by Fusarium species, contaminates global agricultural products and poses significant health risks, particularly to the gastrointestinal (GI) system. DON exposure disrupts ribosomal function, inducing stress responses linked various inflammatory diseases, including bowel disease (IBD). In this study, we elucidate novel regulatory mechanism involving proteins (RPs) RPL13A RPS3, which mediate proinflammatory chemokine production in...
For over a decade, diamide insecticides have been effective against lepidopteran pests like beet armyworm, Spodoptera exigua (Hübner, 1808). However, the evolution of resistance poses challenge to their sustainable use. We identified an I4790 M mutation in S. ryanodine receptor (RyR) gene, but its correlation with varied across field-collected Korean populations exigua. RNA sequencing and differential gene expression analysis were performed investigate other mechanisms. Diamide-resistant...
Abstract CCAAT/enhancer-binding protein homologous (CHOP) is a crucial stress-responsive factor in various mucosal injuries, including cellular translational stress conditions. In this study, chemical ribosome-inactivating stresses were assessed for their effects on stress-inducible CHOP expression and its association with epithelial inflammatory cytokine production. Several representative ribotoxic agents (deoxynivalenol, anisomycin, 15-acetyldeoxynivalenol) enhanced nuclear translocation...
The gastrointestinal mucosa has a remarkable ability to repair damage with the support of epidermal growth factor (EGF), which stimulates epithelial migration and proliferative reepithelialization. For treatment mucosal injuries, it is important develop efficient methods for localized delivery mucoactive biotherapeutics. basic idea in present study came from assumption that an intestinal probiotic vehicle can carry deliver key recombinant medicinal proteins injured target patients ulcerative...
Foodborne aflatoxin B1 (AFB1) and ochratoxin A (OTA) cause genotoxic injury subsequent tumor formation. As a biomarker of oncogenic stimulation by mycotoxins, p53-triggered Mdm2 was assessed in intestinal cancer cells. AFB1 increased reporter expression dose-dependent manner. However, this strongly antagonized OTA treatment. positive transcription factor expression, p53 levels were also alone reduced OTA. With marginal cell death responses, induced p53-mediated S phase arrest...
The fall armyworm (Spodoptera frugiperda, FAW) is an invasive migratory pest that has recently spread to Korea, damaging several corn cultivars with significant economic value. Comparisons of the growth stages FAW were conducted based on preferred feed. Therefore, we selected six maize cultivars, including three categories: (i) commercial waxy (mibaek 2-ho, heukjeom dreamoak); (ii) popcorn (oryun popcorn, oryun 2-ho); and (iii) processing (miheukchal). A effect was observed during larvae...
Excessive and persistent insults during endoplasmic reticulum (ER) stress lead to apoptotic cell death that is implicated in a range of chronic inflammatory diseases cancers. Macrophage inhibitory cytokine 1 (MIC-1), member the transforming growth factor-β superfamily, diversely linked pathogenesis cancer. To investigate precise molecular mechanisms MIC-1 gene regulation, ER its related signals were studied human colon cancer cells. Functionally, played pivotal roles stress-linked death,...
In response to excessive nucleotide-binding oligomerization domain-containing protein 2 (Nod2) stimulation caused by mucosal bacterial components, gut epithelia need activate regulatory machinery maintain epithelial homeostasis. Activating transcription factor 3 (ATF3) is a representative regulator in the negative feedback loop that modulates TLR-associated inflammatory responses. current study, effects of ribosomal stress-induced ATF3 on Nod2-stimulated proinflammatory signals were...
Abstract The diamondback moth ( Plutella xylostella ) is a globally distributed and important economic pest, it has developed resistance to all conventional insecticide classes used in the field. Chlorantraniliprole new chemical class of that acts as conformation‐sensitive activator insect ryanodine receptor (RyR). In present study, field strain (16.3‐fold chlorantraniliprole) was collected Korea lab‐selected with chlorantraniliprole for more than one year. resulting presented 2,157‐fold...
Despite the beneficial actions of antibiotics against bacterial infections, use is a crucial etiological factor influencing microbial dysbiosis-associated adverse outcomes in human health. Based on assumption that gut dysbiosis can provoke behavioral or psychological disorders, present study evaluated anxiety-linked changes mouse model streptomycin-induced dysbiosis. Measuring anxiety-like behavior using light–dark box and elevated plus maze tests indicated streptomycin treatment caused...
The cell-protective features of the endoplasmic reticulum (ER) stress response are chronically activated in vigorously growing malignant tumor cells, which provide cellular growth advantages over adverse microenvironment including chemotherapy. As an intervention with ER responses intestinal cancer preventive exposure to flavone apigenin potentiated superinduction a regulatory transcription factor, activating factor 3 (ATF3), is also known be integral player coordinating response-related...