A5106404340- Advanced Radiotherapy Techniques
- HIV Research and Treatment
- Proteins in Food Systems
- HIV/AIDS Research and Interventions
- Radiation Therapy and Dosimetry
- HIV/AIDS drug development and treatment
- Clinical Nutrition and Gastroenterology
- Microencapsulation and Drying Processes
- Glioma Diagnosis and Treatment
- Radiation Detection and Scintillator Technologies
- Microscopic Colitis
- Hemophilia Treatment and Research
- HIV-related health complications and treatments
- Brain Metastases and Treatment
- Meat and Animal Product Quality
- Radiomics and Machine Learning in Medical Imaging
- Natural product bioactivities and synthesis
- Luminescence and Fluorescent Materials
- Medical Imaging Techniques and Applications
- Pharmacological Effects and Toxicity Studies
- Orthopaedic implants and arthroplasty
- Child Nutrition and Feeding Issues
- Total Knee Arthroplasty Outcomes
- Chemotherapy-induced cardiotoxicity and mitigation
- Viral Infections and Outbreaks Research
Jilin University
2013-2025
Shandong University of Traditional Chinese Medicine
2025
Zhangqiu City People's Hospital
2025
Shandong First Medical University
2024-2025
First Hospital of Jilin University
2012-2025
Tianjin Medical University General Hospital
2024-2025
Soochow University
2025
Inner Mongolia Agricultural University
2025
Chinese PLA General Hospital
2024
Affiliated Hospital of Southwest Medical University
2024
Oral pathology is a commonly reported extraintestinal manifestation of Crohn's disease (CD). The host-microbe interaction has been implicated in the pathogenesis inflammatory bowel (IBD) genetically susceptible hosts, yet limited information exists about oral microbes IBD. We hypothesize that microbiology cavity may differ patients with Our laboratory developed 16S rRNA-based technique known as Human Microbe Identification Microarray (HOMIM) to study microbiome children and young adults...
To examine the role of targeted indirect calorimetry in detecting adequacy energy intake and risk cumulative imbalance a subgroup critically ill children suspected to have alterations resting expenditure. We examined accuracy standard equations used for estimating expenditure relation measured balance over 1 week this cohort.A prospective cohort study.Pediatric intensive care unit tertiary academic center.A pediatric was selected using set criteria calorimetry.Measured from estimated were...
A major barrier to the use of antimicrobial peptides as antibiotics is toxicity or ability lyse eukaryotic cells. In this study, a 26-residue amphipathic α-helical peptide A12L/A20L (Ac-KWKSFLKTFKSLKKTVLHTLLKAISS-amide) was used framework design series D- and L-diastereomeric study relationships helicity biological activities peptides. Peptide measured by circular dichroism spectroscopy demonstrated correlate with hydrophobicity numbers D-amino acid substitutions. Therapeutic index evaluate...
Effective treatments for neurodegenerative diseases need to be developed.MiR132 is abundantly expressed in the brain, and it modulates neuron morphology plays a key role maintaining survival. Regulating miR132 can effectively improve symptoms of Alzheimer's disease. It also reduce cell death after cerebral hemorrhage, microenvironment hematoma lesions provide certain protective effect from brain damage ischemia. MiR132 has great potential treatment ischemia To prevent degradation blood, we...
The average daily gain (ADG) is a critical index for evaluating growth rates in cattle and closely linked to the economic benefits of industry. Heredity one factors affecting cattle. However, molecular mechanisms regulating ADG remain incompletely understood. This study aimed systematically unravel underlying divergence between high (HADG) low (LADG) Angus through integrated multi-omics analyses (microbiome, metabolome, transcriptome), hypothesizing that gut microbiota-host gene-metabolism...
The GEANT4 Monte Carlo code provides many powerful functions for conducting particle transport simulations with great reliability and flexibility. However, as a general purpose code, not all the were specifically designed fully optimized applications in radiation therapy. One of primary issues is computational efficiency, which especially critical when patient CT data have to be imported into simulation model. In this paper we summarize relevant aspects tracking geometry algorithms introduce...
Vitamin D insufficiency [serum 25-hydroxyvitamin (25OHD) concentration less than 20 ng/ml] is prevalent among children with inflammatory bowel disease (IBD), and its treatment has not been studied.The aim of this study was to compare the efficacy safety three vitamin repletion regimens.We conducted a randomized, controlled clinical trial from November 2007 June 2010 at Clinical Translational Study Unit Children's Hospital Boston. The blinded participants investigators.Eligibility criteria...
Vitamin D promotes bone health and regulates the immune system, both important actions for pediatric patients with inflammatory bowel disease (IBD). The supplementation dose that would maintain optimal serum 25-hydroxyvitamin concentration (25OHD ≥ 32 ng/mL) is unknown.The objective of study was to compare two regimens' efficacy safety in maintaining 25OHD children IBD.This a randomized, not blinded, controlled trial.The trial conducted Boston Children's Hospital Clinical Translational Study...
Abstract Drug and alcohol use have been associated with a worse prognosis in short-term cross-sectional analyses of HIV-infected populations, but longitudinal effects on adherence to antiretroviral therapy (ART) clinical outcomes advanced AIDS are less well characterized. We assessed self-reported drug patients, examined their association non-adherence death or disease progression multicenter observational study. defined as reporting missed ART doses the 48 hours before study visits. The...
AIDS Clinical Trials Group (ACTG) A5199 compared the neurological and neuropsychological (NP) effects of 3 antiretroviral regimens in participants infected with human immunodeficiency virus type 1 (HIV-1) resource-limited settings.Participants from Brazil, India, Malawi, Peru, South Africa, Thailand, Zimbabwe were randomized to treatment arms: A (lamivudine-zidovudine plus efavirenz, n = 289), B (atazanavir, emtricitabine, didanosine-EC, 293), C (emtricitabine-tenofovir-disoproxil fumarate...
AIDS Clinical Trials Group study 359 was a controlled of saquinavir with either ritonavir or nelfinavir, together delavirdine, adefovir, both, in indinavir-experienced persons. Saquinavir common all arms, and the investigated relationships among characteristics patients, area under curve (AUC) trough concentrations (C(min)), virologic response. Concentrations were higher when it combined than nelfinavir lower adefovir-containing regimens. Females had AUC C(min) values did males. Higher...
In the present study, 26-residue amphipathic α-helical peptide A12L/A20L (Ac-KWKSFLKTFKSLKKTVLHTLLKAISS-amide) with strong anticancer activity and specificity was used as framework to study effects of helicity peptides on biological activities. Helicity systematically modulated by introducing D-amino acids replace original L-amino non-polar face or polar helix. Peptide measured circular dichroism spectroscopy demonstrated correlate hydrophobicity number acid substitutions. Biological studies...
The application of nanomedicine in inflammatory bowel disease (IBD) has gained significant attention the recent years. As field rapidly evolves, analyzing research trends and identifying hotpots are essential for guiding future advancements, a comprehensive bibliometric can provide valuable insights. current focused on publications from 2001 to 2024, was sourced Web Science Core Collection (WoSCC). CiteSpace VOSviewer were employed visualize authors, institutions, countries, co-cited...
To explore the factors that affect efficacy of knee replacement surgery in hemophiliacs. A retrospective analysis was conducted on 87 patients with hemophilia (PWH) (117knees) who underwent arthroplasty our hospital from January 2012 to December 2020 (mean follow-up 70.8 ± 22 months). General information, surgical information and psychological assessment were collected. The joint evaluated using Hospital for Special Surgery (HSS) score, American Knee Society's Clinical (KSC) Functional (KSF)...