A5045592618- Analytical Chemistry and Chromatography
- Analytical chemistry methods development
- Single-cell and spatial transcriptomics
- Advanced Chemical Sensor Technologies
- Electrochemical sensors and biosensors
- Advanced biosensing and bioanalysis techniques
- Biochemical Analysis and Sensing Techniques
- Cell Image Analysis Techniques
- Dye analysis and toxicity
- Analytical Methods in Pharmaceuticals
- Analytical Chemistry and Sensors
- Chemical Analysis and Environmental Impact
- Covalent Organic Framework Applications
- Electrochemical Analysis and Applications
- Microfluidic and Capillary Electrophoresis Applications
- Gene Regulatory Network Analysis
- Advanced Nanomaterials in Catalysis
- Luminescence and Fluorescent Materials
- Pesticide Residue Analysis and Safety
- Immune cells in cancer
- Food Quality and Safety Studies
- Metal-Organic Frameworks: Synthesis and Applications
- Advanced Drug Delivery Systems
- Traditional Chinese Medicine Analysis
- Extracellular vesicles in disease
Yangzhou University
2020-2025
Zhejiang Shuren University
2019-2024
Wuchang University of Technology
2021
University of Birmingham
2020
Hangzhou Academy of Agricultural Sciences
2019
Zhejiang University
2004-2017
Salk Institute for Biological Studies
2014-2017
Howard Hughes Medical Institute
2016
Tongde Hospital of Zhejiang Province
2016
Zhongshan Hospital of Xiamen University
2016
Abstract The codling moth Cydia pomonella , a major invasive pest of pome fruit, has spread around the globe in last half century. We generated chromosome-level scaffold assembly including Z chromosome and portion W chromosome. This reveals duplication an olfactory receptor gene ( OR3 ), which we demonstrate enhances ability C. to exploit kairomones pheromones locating both host plants mates. Genome-wide association studies contrasting insecticide-resistant susceptible strains identify...
CsPbX3 perovskite nanocrystal (NC) is considered as an excellent optical material and widely applied in optoelectronics. However, its poor water stability impedes study enzyme-like activity, further inhibits application biomimetic cascade catalysis. Herein, for the first time, oxidase-like ascorbate activities of amphiphilic polymer capped are demonstrated, catalytic mechanism explored. Furthermore, all-nanozyme system (multifunctional CsPbBr3 @Zr-metal organic framework (Zr-MOF) Prussian...
While single-cell technologies have greatly advanced our comprehension of human brain cell types and functions, studies including large numbers donors multiple regions are needed to extend understanding heterogeneity. Integrating atlas-level data presents a chance reveal rare cellular heterogeneity across regions. Here we present the Brain Cell Atlas, comprehensive reference atlas cells, by assembling from 70 103 mouse throughout major developmental stages regions, covering over 26.3 million...
Tumor-derived extracellular vesicles (T-EVs) PD-L1 are an important biomarker for predicting immunotherapy response and can help us understand the mechanism of resistance to immunotherapy. However, this is due interference from a large proportion nontumor-derived EVs. It still challenging accurately analyze T-EVs in complex human fluids. Herein, simple ultrasensitive method based on dual-aptamer-proximity ligation assay (PLA)-guided rolling circle amplification (RCA) analysis was developed....
The accumulation of massive single-cell omics data provides growing resources for building biomolecular atlases all cells human organs or the whole body. true assembly a cell atlas should be cell-centric rather than file-centric. We developed unified informatics framework seamless and built Ensemble Cell Atlas (hECA) from scattered data. hECA v1.0 assembled 1,093,299 labeled 116 published datasets, covering 38 11 systems. invented three new methods applications based on assembly: "in data"...
A series of NH2-functionalized nano-sized magnetic metal–organic frameworks (MOFs) were prepared in this study for Cr(VI) removal from wastewater. It was observed that not only the morphological, i.e., orientation growth N-doped and iron-based frameworks, but also adsorption MOFs is largely related to used amount ammonium hydroxide preparation. For example, with increasing amounts preparation, morphology changed spherical cube triangular cone. Moreover, maximum capacity spherical-magnetic...
Metal-organic frameworks (MOFs) show excellent catalytic activity and have been widely applied in diagnosis of diseases tumors. However, current assay methods usually involve cumbersome configurations complicated procedures, which inhibit their practical applications. Hence, a Cu-Ni MOF/carbon printed electrode (CPE)-based integrated electrochemical immunosensor was constructed for highly sensitive efficient determination carcinoembryonic antigen (CEA). First, conductive carbon ink...