A5103884452- Probiotics and Fermented Foods
- Helicobacter pylori-related gastroenterology studies
- Gut microbiota and health
- Microbial Metabolism and Applications
- Genomics and Chromatin Dynamics
- Gastrointestinal motility and disorders
- Immune cells in cancer
- Epigenetics and DNA Methylation
- Food Quality and Safety Studies
- Single-cell and spatial transcriptomics
- Insect Utilization and Effects
- Dental Health and Care Utilization
- Neuroinflammation and Neurodegeneration Mechanisms
- Oral microbiology and periodontitis research
- Birth, Development, and Health
- Microbial Metabolites in Food Biotechnology
- Health, Environment, Cognitive Aging
- Aquaculture disease management and microbiota
- Per- and polyfluoroalkyl substances research
- Microtubule and mitosis dynamics
Guangxi Academy of Fishery Sciences
2024
Guangzhou Experimental Station
2024
State Key Laboratory of Food Science and Technology
2011-2024
Jiangnan University
2019-2024
Nanchang University
2011
While single-cell technologies have greatly advanced our comprehension of human brain cell types and functions, studies including large numbers donors multiple regions are needed to extend understanding heterogeneity. Integrating atlas-level data presents a chance reveal rare cellular heterogeneity across regions. Here we present the Brain Cell Atlas, comprehensive reference atlas cells, by assembling from 70 103 mouse throughout major developmental stages regions, covering over 26.3 million...
Integrating single-cell omics data at an atlas scale enhances our understanding of cell types and disease mechanisms. However, the integration processed by different normalisation methods can lead to biases, such as unexpected batch effects gene expression distortion, leading misinterpretations in downstream analysis. To address these challenges, we present scDenorm, algorithm that reverts normalised raw counts, preserving integrity original measurements ensuring consistent processing during...
Streptococcus mutans is recognized as the main cause of dental caries, and formation a plaque biofilm required for caries development. This study aimed to determine inhibitory effect Lactobacillus plantarum FB-T9 on S. in vitro prevention treatment rats. During experiments, exhibited good bacteriostatic ability plate competition assay. strain also significantly reduced biomass viability biofilms induced structural damage during early (6 h), middle (12 h) late (24 stages formation. In 70-day...
The three-dimensional genome structure organized by CTCF is required for development. Clinically identified mutations in have been linked to adverse developmental outcomes. Nevertheless, the underlying mechanism remains elusive. In this investigation, we explore regulatory roles of a clinically relevant R567W point mutation, located within 11
The growth environment significantly influences the intestinal microbiota of aquatic organisms. We investigated composition and functional differences in red claw crayfish (Cherax quadricarinatus) rice fields (RB) ponds (PB) by 16S rDNA high-throughput sequencing technology. results indicate that Shannon, Simpson, Sobs, Chao1, ACE indices PB are all higher than those RB, demonstrating greater diversity richness microbiota. dominant phyla Cherax quadricarinatus were Proteobacteria,...
ABSTRACT Cathartic colon, a form of slow‐transit constipation, arises from prolonged stimulant laxative use and is associated with intestinal barrier impairment enteric nervous system damage. We identified Bifidobacterium bifidum CCFM1163 as an effective agent for alleviating cathartic colon; however, the underlying mechanisms remain unclear. This study first administered live, dead, supernatant forms to colon mice, finding that only live bacteria were effective. Non‐targeted targeted...
Numerous studies have demonstrated a close correlation between the intestinal microbiota of aquatic organisms and their external environment. Paddy field cultivation has much longer history in China. Therefore, we selected Cherax quadricarinatus two individuals large small size to study diversity functional differences gut farming environments, paddy ponds, using 16SrDNA high-throughput sequencing. The results showed that dominant phyla were Proteobacteria, Tenericutes, Firmicutes. phylum...