Abstract Aim To explore the trajectories of consciousness recovery and prognosis‐associated predictors in children with prolonged disorder (pDoC). Method This single‐centre, retrospective, observational cohort involved 134 (87 males, 47 females) diagnosed pDoC hospitalized at Department Rehabilitation Children's Hospital Chongqing Medical University China. The median onset age was 30 (interquartile range [IQR] 18–54) months, ages ranging from 3 to 164 months. Least absolute shrinkage...

Central nervous system infection is the most common and severe clinical subtype of ectopic paragonimiasis. Intraspinal paragonimiasis rarely reported. This study aimed to provide experience for diagnosis treatment strategies pediatric intraspinal We performed a retrospective analysis patients hospitalized between January 1, 2015, December 31, 2021. Nine were included. The median age was 9 years. Clinical symptoms mainly included weakness (9/9), sensory disturbances (6/9), urinary retention...

Background and Objective Magnetic resonance cholangiopancreatography (MRCP) is widely accepted for visualization of the biliary system. However, sensitivity specificity MRCP diagnosis atresia (BA) are still not fully elucidated. This study aimed to investigate diagnostic value three-dimensional (3D-MRCP) BA in a large cohort cholestatic infants neonates. Methods One hundred ninety patients with infant jaundice underwent 3D-MRCP one or more following: (1) intraoperative cholangiography, (2)...

Mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS) is one of the most common inherited mitochondrial disorders. Due to high clinical genetic heterogeneity MELAS, it still a major challenge for clinicians accurately diagnose disease at an early stage. Herein, we evaluated neuroimaging findings MELAS m.3243A>G mutation in MT-TL1 analyzed possible underlying pathogenesis episodes.Fifty-nine imaging studies 24 patients who had confirmed diagnosis (MT-TL1;...

Abstract Background Existing evidence has shown that mesenchymal stem cells (MSCs) can undergo malignant transformation, which is a serious limitation of MSC-based therapies. Therefore, it necessary to monitor transformation MSCs via noninvasive imaging method. Although reporter gene-based magnetic resonance (MRI) been successfully applied longitudinally MSCs, this technique cannot distinguish the before and after transformation. Herein, we investigated feasibility using tumor-specific...

Background Preliminary studies have shown that diffusion tensor imaging (DTI) is helpful in evaluating liver disorders. However, there no published literature on the use of DTI diagnosis biliary atresia (BA). This study aimed to investigate diagnostic value average apparent coefficient (ADC) and fractional anisotropy (FA) measured using for BA neonates infants. Methods Fifty-nine patients with infant jaundice were included this study. was performed b factors 0 1000 s/mm2. Liver fibrosis...

Computed tomography (CT) has been widely used for the diagnosis of pelvic rhabdomyosarcoma (RMS) in children. However, it is difficult to differentiate RMS from other malignancies. This study aimed analyze and select CT features by using least absolute shrinkage selection operator (LASSO) logistic regression established a Fisher discriminant analysis (FDA) model quantitative pediatric RMS. A total 121 patients who were diagnosed with neoplasms included this study. The assigned an group (n =...

Intraspinal tuberculoma is a rare disease in children, and its imaging findings have been described only few case reports. This study aimed to investigate the magnetic resonance (MRI) features of pediatric intraspinal explore possible pathogenesis disease. The clinical MRI data 24 child patients with (such as 6 cases intramedullary tuberculoma, 8 intradural extramedullary 10 epidural tuberculoma) were retrospectively analyzed. All underwent plain contrast-enhanced MR scans. diagnosis was...

Background It is crucial to preoperatively assess the arteries of hands in congenital syndactyly malformation (CSM) patients because this information can affect therapeutic outcome and prognosis. Objective To investigate value a contrast-enhanced three-dimensional water-selective cartilage scan for preoperative evaluation CSM children. Materials Methods Contrast-enhanced 3.0 T magnetic resonance imaging (MRI) performed 16 clinically diagnosed with 17 affected hands. The were displayed focus...

Background The prognosis of prolonged disorders consciousness (pDoC) in children has consistently posed a formidable challenge clinical decision-making. Objective This study aimed to develop machine learning (ML) model based on conventional structural magnetic resonance imaging (csMRI) predict outcomes with pDoC. Methods A total 196 pDoC were included this study. Based the states 1 year after brain injury, categorized into either favorable group or poor group. They then randomly assigned...

Little is known about the precise impaired patterns of white matter (WM) fiber tracts in preschool-aged children with autism spectrum disorder (ASD). Thus, we used diffusion tensor imaging (DTI)-based automated quantification (AFQ) to explore changes WM ASD and its correlation severity clinical manifestations.

Prader-Willi syndrome (PWS) is a neurodevelopmental disorder characterized by dysplasia in early life. Psychoradiology studies have suggested that mental and behavioral deficits individuals with PWS are linked to abnormalities brain structural functional networks. However, little known about changes network-based structural-functional coupling structural/functional topological properties their correlations developmental scales children PWS. Here, we acquired diffusion tensor imaging...

To develop MRI-based radiomics models from the lesion level to subject and assess their value for differentiating myelin oligodendrocyte glycoprotein antibody-related disease (MOGAD) non-MOGAD acute demyelinating syndromes in pediatrics.

INTRODUCTION Congenital vascular rings (VRs) are a group of rare cardiovascular anomalies that result from abnormal embryonic development the paired aortic arches or branching pulmonary arteries. Clinical presentation VR depends on its anatomy, degree, and site compression. Stridor, recurrent upper respiratory tract infections feeding difficulty were frequent symptoms VR. Barium swallow test, echocardiography, computed tomography (CT) magnetic resonance imaging (MRI) present as effective...

Background MicroRNAs (miRs) have been shown to be closely associated with the occurrence and development of tumors potential as diagnostic therapeutic targets. The detection miRs by noninvasive imaging technology is crucial for deeply understanding their biological functions. Our aim was develop a novel miR-21-responsive gene reporter system magnetic resonance (MRI) visualization miR-21 dynamics in neuroblastoma. Methods ferritin heavy chain (FTH1) modified addition 3 copies sequence...