A5040808358- Lymphoma Diagnosis and Treatment
- Chronic Lymphocytic Leukemia Research
- Dialysis and Renal Disease Management
- CAR-T cell therapy research
- Neurological and metabolic disorders
- Liver Disease Diagnosis and Treatment
- Cardiac Imaging and Diagnostics
- Acute Myocardial Infarction Research
- Viral Infections and Vectors
- Mosquito-borne diseases and control
- Diabetes Management and Research
- Photoacoustic and Ultrasonic Imaging
- Ultrasound Imaging and Elastography
- Cardiovascular Function and Risk Factors
- Heparin-Induced Thrombocytopenia and Thrombosis
- Diabetic Foot Ulcer Assessment and Management
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Heart Failure Treatment and Management
- HIV/AIDS Research and Interventions
- Electrolyte and hormonal disorders
- Respiratory Support and Mechanisms
- Traumatic Brain Injury and Neurovascular Disturbances
- Cardiac, Anesthesia and Surgical Outcomes
- Diagnosis and treatment of tuberculosis
- Ultrasonics and Acoustic Wave Propagation
University of Pennsylvania
2010-2024
Vanderbilt University
2015-2024
Berman Center for Outcomes and Clinical Research
2023-2024
Abramson Cancer Center
2017-2018
Sidney Kimmel Cancer Center
2017
UPMC Hillman Cancer Center
2013-2015
Hospital of the University of Pennsylvania
2009-2012
Coronary computerized tomographic angiography (CTA) has high correlation with cardiac catheterization and been shown to be safe cost-effective when used for rapid evaluation of low-risk chest pain patients from the emergency department (ED). The long-term outcome discharged ED negative coronary CTA not well studied.The authors prospectively evaluated consecutive low- intermediate-risk who received in a potential acute syndrome (ACS). Patients cocaine use, known cancer, significant...
Lenalidomide, an immunomodulatory agent that enhances antibody-dependent cell-mediated cytotoxicity, has the potential to synergize with rituximab, anti-CD20 mAb. We hypothesized addition of lenalidomide rituximab would improve clinical outcomes in patients B-cell lymphomas who were previously resistant, defined as no response or progression lymphoma within 6 months rituximab-based therapy.We conducted a single-center, phase II trial indolent mantle cell resistant. Patients received 10 mg...
Abstract Patients with B-cell lymphomas have altered cellular components of vaccine responses due to malignancy and therapy, the optimal timing vaccination relative therapy remains unknown. Severe acute respiratory syndrome coronavirus 2 vaccines created an opportunity for new insights in because patients were challenged a novel antigen across multiple phases treatment. We studied serologic messenger RNA response retrospective prospective cohorts lymphoma chronic lymphocytic leukemia, paired...
ACADEMIC EMERGENCY MEDICINE 2011; 18:1–9 © 2011 by the Society for Academic Emergency Medicine Objectives: Observational studies of patients with cocaine-associated myocardial infarction have suggested more coronary disease than expected on basis patient age. The study objective was to determine whether cocaine use is associated in low- intermediate-risk emergency department (ED) potential acute syndrome (ACS). Methods: authors conducted a cross-sectional < 60 years age who received...
Noncontrast perfusion ultrasound imaging remains challenging due to spectral broadening of the tissue clutter signal caused by patient and sonographer hand motion. To address this problem, we previously introduced an adaptive demodulation scheme suppress bandwidth prior high-pass filtering. Our initial implementation used single plane wave power Doppler a conventional filter. Recent advancements in beamforming filtering have been proposed for improved slow flow imaging, including coherent...
Objectives To determine whether patients with elevated creatinine who present to the emergency department (ED) potential acute coronary syndrome (ACS) are at an increased risk of myocardial infarction (AMI) or 30-day cardiovascular (CV) events. Methods A secondary analysis a cohort study presenting ED ACS serum measurements. Research assistants collected demographics, history, symptoms, hospital course and follow-up. Outcomes measured were in-hospital AMI CV events (death, nonfatal AMI,...
In traditional shear wave elasticity imaging (SWEI), velocity is measured away from the acoustic radiation force (ARF) axis. Instead, we measure time-to-peak displacement of tissue directly along ARF Measuring displacements this axis rather than off-axis simplifies hardware required for quantifying stiffness. Previously method has been demonstrated, but measurement variance was too high practical feasibility. To reduce stiffness estimation error, apply our Bayesian estimator. evaluate...
This research quantitatively estimates stiffness by measuring the time-to-peak displacement directly along acoustic radiation force (ARF) axis in contrast to shear wave elasticity imaging (SWEI) that measures velocity at lateral locations. We have shown previously simulation results an advanced estimator reduces variability final estimate. Here, we tested on-axis approach 10 simulations and 5 phantoms. created a lookup table of as function depth. generated look-up using 3D FEM model coupled...