Harsh Sharma
A5101687893- CAR-T cell therapy research
- Immunotherapy and Immune Responses
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Infectious Encephalopathies and Encephalitis
- Orthopaedic implants and arthroplasty
- Cancer Immunotherapy and Biomarkers
- Hip and Femur Fractures
- Medical Imaging and Analysis
- Bone fractures and treatments
- Hereditary Neurological Disorders
- SARS-CoV-2 detection and testing
- Peripheral Neuropathies and Disorders
- Autoimmune Neurological Disorders and Treatments
- Neurogenetic and Muscular Disorders Research
- Parvovirus B19 Infection Studies
- Long-Term Effects of COVID-19
- Virus-based gene therapy research
- Thermal Regulation in Medicine
- Chronic Lymphocytic Leukemia Research
- Lymphoma Diagnosis and Treatment
- Artificial Intelligence in Healthcare
- Diabetic Foot Ulcer Assessment and Management
Kasturba Medical College, Manipal
2024
Manipal Academy of Higher Education
2024
Novartis (Switzerland)
2024
Institute of Immunology
2024
University of Pennsylvania
2021-2023
SRM Institute of Science and Technology
2023
Philadelphia University
2022
Immune memory after vaccination Vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has proven highly effective at preventing COVID-19. However, the evolution of viral variants, and waning antibody levels over time, raise questions regarding longevity vaccine-induced immune protection. Goel et al . examined B T lymphocyte responses in individuals who received SARS-CoV-2 messenger RNA vaccines. They performed a 6-month longitudinal study never had infection...
ABSTRACT SARS-CoV-2 mRNA vaccines have shown remarkable efficacy, especially in preventing severe illness and hospitalization. However, the emergence of several variants concern reports declining antibody levels raised uncertainty about durability immune memory following vaccination. In this study, we longitudinally profiled both cellular responses naïve recovered individuals from pre-vaccine baseline to 6 months post-mRNA Antibody neutralizing titers decayed peak but remained detectable all...
Abstract Patients with B-cell lymphomas have altered cellular components of vaccine responses due to malignancy and therapy, the optimal timing vaccination relative therapy remains unknown. Severe acute respiratory syndrome coronavirus 2 vaccines created an opportunity for new insights in because patients were challenged a novel antigen across multiple phases treatment. We studied serologic messenger RNA response retrospective prospective cohorts lymphoma chronic lymphocytic leukemia, paired...
Abstract Despite a clear role in protective immunity, the durability and quality of antibody memory B cell responses induced by mRNA vaccination, particularly 3 rd dose vaccine, remains unclear. Here, we examined cohort individuals sampled longitudinally for ∼9-10 months after primary 2-dose vaccine series, as well ∼3 dose. Notably, decay slowed significantly between 6- 9-months post-primary essentially stabilizing at time Antibody also continued to improve least 9 vaccination. Spike-...
Bickerstaff brainstem encephalitis (BBE) and Miller-Fisher syndrome (MFS) are rare post-infectious neurological syndromes, usually involving 'anti-GQ1b ganglioside' antibodies. Both syndromes present with ophthalmoplegia ataxia. However, BBE is differentiated by altered consciousness or pyramidal signs (central nervous system involvement), while MFS has areflexia (peripheral involvement). Here, we discuss a case of an elderly woman, who, after initial episode upper respiratory tract...
Diabetes is a type of illness or problem which can't be treated surgically operated on.Lack consciousness regarding lifestyle can easily cause diabetes.Diabetes generally caused because gain weight, laziness, not taking proper diet, etc.A person who having diabetes should very proactive about his health as it also lead to death more severe complications.One such complications Diabetic Foot Ulcers(DFU).One the leading reasons in world, result like diabetic foot ulcers.(DFU).A patient's may...
ABSTRACT Patients with B-cell lymphomas have altered cellular components of vaccine responses due to the malignancies and therapies. The optimal timing administration relative chemotherapy immunotherapy remains unknown. SARS-CoV-2 campaign created a unique opportunity gather insights into because patients were challenged novel antigen across multiple phases lymphoma management. We studied retrospective prospective cohorts CLL who received an mRNA-based paired serologic response treatment...