A5014293785- Diamond and Carbon-based Materials Research
- Natural Antidiabetic Agents Studies
- Hemoglobin structure and function
- Metabolism, Diabetes, and Cancer
- Mangiferin and Mango Extracts
- Bioactive Compounds and Antitumor Agents
- Diet, Metabolism, and Disease
- Analytical Chemistry and Sensors
- Gastric Cancer Management and Outcomes
- Porphyrin and Phthalocyanine Chemistry
- Bioactive natural compounds
- Higher Education Governance and Development
- Innovative Microfluidic and Catalytic Techniques Innovation
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Carbon Nanotubes in Composites
- Diabetes Treatment and Management
- Online and Blended Learning
- Drug-Induced Hepatotoxicity and Protection
- Advances in Cucurbitaceae Research
- 3D Printing in Biomedical Research
- Pharmacology and Nanomedicine Research
- Ethnobotanical and Medicinal Plants Studies
- Nitric Oxide and Endothelin Effects
- Force Microscopy Techniques and Applications
- Metastasis and carcinoma case studies
University of Groningen
2020-2024
University Medical Center Groningen
2020-2024
Jashore University of Science and Technology
2012-2021
We demonstrated nanoscale MRI of metabolism in single isolated mitochondria and within living cells using NV centers diamond.
Free-radical generation is suspected to play a key role in cardiovascular diseases. Another crucial factor shear stress. Human umbilical vein endothelial cells (HUVECS), which form the lining of blood vessels, require physiological stress activate many vasoactive factors. These are needed for maintaining vascular cell functions such as nonthrombogenicity, regulation flow, and tone. Additionally, clots at regions high within vessel. Here, we use new method called diamond magnetometry allows...
Ethanolic extracts of some fruits Cucurbitaceae family such as Cucumis sativus (cucumber), Lagenaria siceraria (white pumpkin), Luffa acutangula (ridge gourd), Benincasa hispida (ash Citrullus lanatus (sweet melon) and Cucarbita maxima (pumpkin) have been studied for their hypoglycemic effects on alloxan induced diabetic rats (AIDRs). Screening results suggested that among the tested potency follows: cucumber > white pumpkin ridge gourd. These three fruit-extracts were further...
The higher education sector is facing challenges to meet the market demand of skilled workers in era 4th Industrial Revolution (4IR). This study explores educational supply chain management systems Bangladesh. Qualitative data were collected through interview with stakeholders and analyzed conceptualize a thematic framework for chain. Findings identify key skills required developing market-ready workforce ways incorporate curriculum. findings also illustrate changes university culture,...
Acetaminophen overdoses cause cell injury in the liver. It is widely accepted that liver toxicity initiated by reactive N-acetyl-para-aminophenol (APAP) metabolite N-acetyl-p-benzoquinone imine (NAPQI), which first depletes glutathione and then irreversibly binds to mitochondrial proteins nuclear DNA. As a consequence, respiration inhibited, DNA strands break. NAPQI also promotes oxidative stress since one of main free-radical scavengers cell. However, so far it unknown where exactly free...
We investigate differences in nanodiamond uptake between cells types and from the same type.
Bombax ceiba (B.ceiba), a member of the Malvaceae family, has widely been used by rural practitioners for various ailments from ancient civilization.Although different parts this plant are known to have several biological activities, very little is about effects young roots B. (BCYR) on diabetes and hepatic toxicity.Therefore, present study was undertaken investigate BCYR toxicity in Alloxan-Induced Diabetic Mice (AIDM).The dried coarse powder extracted with ethanol (Et-BCYR) cold extraction...
Surface functionalization and uptake protocols had dramatic effects on cell viability, internalization efficiency, aggregation intracellular distribution of fluorescent nanodiamonds carrying zwitterionic capped azide groups.
While the microenvironment is known to alter cellular behavior in terms of metabolism, growth and degree endoplasmic reticulum stress, its influence on nanoparticle uptake not yet investigated. Specifically, it clear if cells cultured a ingest different amounts nanoparticles than macroenvironment (for example petri dish). To answer this question, here we used J774 murine macrophages fluorescent nanodiamonds (FND) as model system systematically compare efficiency dish microfluidic channel....
Hypercholesterolemia is one of the important causes cardiovascular disease related mortality and morbidity recently it has become a significant issue in public health problem developing countries. The purpose study was to see effect glycine max (soy bean) on serum lipid profile experimentally induced hyperlipidemic rats. by high cholesterol diet containing 1% olive oil. This done 24 long Norwegian rats (Rattus norvegicus) weighing about 200-210 gram. For convenience, divided into Experiment...
Abstract Since wound healing requires cells to repopulate a damaged area, cell migration is essential. In addition, plays crucial role in cancer metastasis. Whether tumour can invade tissue and metastasize factor determining their malignancy or other words hallmark of (Lazebnik Nat Rev Cancer 10: 232–233, 2010, https://doi.org/10.1038/nrc2827 ). Nanodiamonds potentially offer powerful tool investigate these processes. Due unprecedented photostability, they function as long-term fluorescent...
Abstract Background Diabetic is one of the fundamental persuasive diabetic nephropathy and significantly sparks off kidney diseases end stage renal failure globally. Method The current research was carried out to evaluate hypoglycemic potential nephroprotective effect ethanolic extract Mikania scandens leaves by using alloxan-induced (DN) mice. mice were intraperitoneally treated with (200 mg/kg) standard (120 metformin HCL solution up 22 days. During this treatment period, we collected...
Abstract Targeting apoptosis is a promising approach to inhibit the abnormal cell proliferation of cancer progression. Existing anti-apoptotic drugs, many derived from chemical substances, have often failed combat development and Therefore, identification apoptosis-inducing anticancer agents plant-derived sources has become key aim in research. The present study was designed explore regulation by Tabebuia pallida ( T. ) using an Ehrlich Ascites Carcinoma (EAC) mouse model compositional...
Pleurotusosteratus (family: Pleurotaceae) and Ganodermalucidum ganodermataceae) are common edible mushrooms in Bangladesh. Ethyl acetate extract of were used to find out their hypoglycaemicactivity alloxan induced diabetic mice. reduced blood glucose level 39.56% 43.27% respectively at 24 hours after intrapertitoneal administration (P<0.005) inalloxan diabeticmice.The possible mechanism hypoglycemic action is due the increased uptake liver cells because it markedly lowers levels diabeticmice.
Six marketed oral antidiabetic metformin tablets in Bangladesh have been studied for their drug content, release profile and glucose lowering capacities. This sort of study is a good indicator vivo evaluation the quality an preparation. Marketed preparations metformin-HCl from different manufacturers were randomly chosen this study. The content was within United State Pharmacopoeia (USP) specified limit (95-105%) all cases. blood levels investigated streptozotocin-induced diabetic rats...