A5016353535- Supramolecular Self-Assembly in Materials
- Advanced biosensing and bioanalysis techniques
- Iron oxide chemistry and applications
- Clay minerals and soil interactions
- Brain Tumor Detection and Classification
- DNA and Nucleic Acid Chemistry
- Mesoporous Materials and Catalysis
- High Temperature Alloys and Creep
- Heme Oxygenase-1 and Carbon Monoxide
- Chemical Synthesis and Analysis
- Lipid Membrane Structure and Behavior
- Aquatic Ecosystems and Phytoplankton Dynamics
- Optical Systems and Laser Technology
- Environmental remediation with nanomaterials
- High Entropy Alloys Studies
- Supercapacitor Materials and Fabrication
- High-Temperature Coating Behaviors
- Water Treatment and Disinfection
- Artificial Intelligence in Healthcare
- Pickering emulsions and particle stabilization
- AI in cancer detection
- Bacterial biofilms and quorum sensing
- Advanced Photocatalysis Techniques
- Diamond and Carbon-based Materials Research
- Antimicrobial Peptides and Activities
Biogen (United States)
2023-2025
Liaoning Technical University
2024
Qufu Normal University
2024
Tulane University
2014-2022
State Key Laboratory of Pollution Control and Resource Reuse
2018-2022
Tongji University
2018-2022
State Key Laboratory of Powder Metallurgy
2021
Huaiyin Normal University
2021
Central South University
2021
Northeast Forestry University
2021
Naturally occurring halloysite clay nanotubes are effective in stabilizing oil-in-water emulsions and can serve as interfacially-active vehicles for delivering oil spill treating agents. Halloysite adsorb at the oil-water interface stabilize that stable months. Cryo-scanning electron microscopy (Cryo-SEM) imaging of shows these assemble a side-on orientation form networks on through end-to-end linkages. For application treatment marine spills, were successfully loaded with surfactants...
A series of amphiphilic ionic peptoid block copolymers where the total number (1 or 3) and position monomers along polymer chain are precisely controlled have been synthesized by submonomer method. Upon dissolution in water at pH = 9, peptoids self-assemble into small spherical micelles having hydrodynamic radius ∼5–10 nm range critical micellar concentration (CMC) 0.034–0.094 mg/mL range. Small-angle neutron scattering (SANS) analysis solutions revealed unprecedented dependence structure on...
A series of ABC triblock copolypeptoids [i.e., poly(
Abstract Random and diblock copolymers of 2‐( N,N ‐dimethylamino)ethyl methacrylate butyl are prepared by ATRP. As mimics cationic antimicrobial peptides, the random show similar activities. In contrast, have much lower hemolytic activities than copolymers. The cell selectivity (HC 50 /MIC, where HC is concentration to lyse 50% human red blood cells MIC minimum inhibit bacterial growth) 150 27 500 times higher that with compositions. magnified image
The carbonization of hydrophilic particle surfaces provides an effective route for tuning wettability in the preparation particle-stabilized emulsions. naturally occurring halloysite clay nanotubes (HNT) is successfully tuned by selective negatively charged external HNT surface. positively charge chitosan biopolymer binds to surface electrostatic attraction and hydrogen bonding, yielding carbonized (CHNT) on pyrolysis inert atmosphere. Relative native HNT, oil emulsification ability CHNT at...
This paper evaluates questions generated by LLMs from context, comparing them to human-generated across six dimensions. We introduce an automated LLM-based evaluation method, focusing on aspects like question length, type, context coverage, and answerability. Our findings highlight unique characteristics of LLM-generated questions, contributing insights that can support further research in quality downstream applications.
Substitution of a nonbridging oxygen for sulfur on the phosphodiester backbone an oligonucleotide enhances its pharmacokinetic properties. This substitution creates new chiral center at phosphorus atom linkage. Oligonucleotides with >10 phosphorothioate linkages are therefore mixtures thousands to hundreds diastereomers. From chemistry, manufacturing, and control perspective, it is essential ensure manufacturing consistency product quality by controlling factors that influence...
Abstract Carbon monoxide ( CO ) poisoning is one of the leading causes toxicity‐related mortality and morbidity worldwide, primarily manifested by acute delayed central nervous system CNS injuries other organ damages. However, its definite pathogenesis poorly understood. The aim this study was to explore ultrastructural functional impairment mitochondria protection sulphoraphane SFP at different dosages on hippocampus neurons in rats after exposure . We found that could induce advanced...
The aim of the present study was to investigate protective effect and underlying mechanism tetramethylpyrazine (TMP) on renal ischemia reperfusion injury (RIRI) in rats, which refers caused by restoration blood supply kidney after a period ischemia. Sprague‑Dawley rats were randomly divided into Sham group, ischemia‑reperfusion (I/R) group TMP group. hydrochloride (40 mg/kg, 6 h intervals) given via intraperitoneal injection immediately 24 tissues taken for follow‑up experiments....
There is evidence that cattle grazing in forests limits big cat abundance. concern, too, about competition with wild ungulate prey through bottom-up effects on vegetation. Hence, there have been calls to remove or control forest livestock aid of restoring endangered large carnivores and their prey. To help inform scientific debate decision making, we explored cattle-vegetation-prey dynamics Northeast Tiger Leopard National Park, northeast China present a reappraisal the context coexistence...
Stereochemical comparability is critical for ensuring manufacturing consistency in therapeutic phosphorothioate oligonucleotides. Currently, analytical methods this assessment are limited. We hereby report on a novel protocol capable of detecting stereochemistry change single linkage by employing nuclease P1 digestion the oligonucleotide with subsequent LCMS analysis resulting fragments. The method proves valuable establishing stereochemical and therapeutics.
In the study of spatiotemporal geographical phenomena, space–time interpolation method is widely applied, and demands for computing speed accuracy are increasing. For nonprofessional modelers, utilizing quickly a challenge. To solve this problem, classical ordinary kriging algorithm was selected expanded to algorithm. Using OpenCL framework integrate central processing unit (CPU) graphic (GPU) resources, parallel implemented, three experiments were conducted in work verify results. The...
We report the ability of hydrophobically modified polypeptoids (HMPs), which are amphiphilic pseudopeptidic macromolecules, to connect across lipid bilayers and thus form layered structures on liposomes. The HMPs obtained by attaching hydrophobic decyl groups at random points along polypeptoid backbone. Although native (with no hydrophobes) have effect liposomal structure, remodel unilamellar liposomes into with comparable diameters but multiple concentric bilayers. transition from...
The aggregation behavior of cyclic polypeptoids has been studied using experiments and simulations.
Dense nonaqueous phase chlorinated compounds such as trichloroethylene (TCE) and tetrachloroethylene (PCE) are widespread groundwater soil contaminants which cause long-term environmental pollution. Extensive efforts have been carried out to develop materials for in situ remediation particularly using nanoscale zerovalent iron (NZVI) reduce TCE relatively innocuous products ethane ethylene. A novel technology is described here that uses earth-abundant natural tubular aluminosilicate clays...
α-Fe<sub>2</sub>O<sub>3</sub> microspheres with hollow and yolk–shell (X@Fe<sub>2</sub>O<sub>3</sub>) morphologies are fabricated through synthesis in the confined environment of aerosol droplets.
Peptoids are highly biocompatible pseudopeptidic polyglycines with designable substituents on the nitrogen atoms. The therapeutic and drug-carrying potential of these materials requires a fundamental understanding their interactions lipid bilayers. In this work, we use amphiphilic polypeptoids up to 100 monomeric units where significant fraction (26%) atoms functionalized decyl groups (hydrophobes) that insert into bilayer through hydrophobic effect. These hydrophobically modified (HMPs)...