A5055063119- Genetic diversity and population structure
- Venomous Animal Envenomation and Studies
- Genomics and Phylogenetic Studies
- Amphibian and Reptile Biology
- Species Distribution and Climate Change
- Plant-Microbe Interactions and Immunity
- Animal Ecology and Behavior Studies
- Spider Taxonomy and Behavior Studies
- Plant Pathogens and Fungal Diseases
- Bat Biology and Ecology Studies
- Plant Pathogenic Bacteria Studies
- SARS-CoV-2 and COVID-19 Research
- Yersinia bacterium, plague, ectoparasites research
- Genetic Associations and Epidemiology
- Forest Insect Ecology and Management
- Identification and Quantification in Food
- Evolution and Paleontology Studies
- Molecular Biology Techniques and Applications
- Plant and animal studies
- Coleoptera Taxonomy and Distribution
- Fungal Plant Pathogen Control
- Subterranean biodiversity and taxonomy
- Forensic Entomology and Diptera Studies
- Fish Biology and Ecology Studies
- Insect and Pesticide Research
Hebei Agricultural University
2020-2024
Institute of Zoology
2005-2023
University of Bristol
2022
Chinese Academy of Sciences
2005-2021
Beijing Institute of Genomics
2016-2021
Shanghai Center For Bioinformation Technology
2020
University College London
2017
University of Chinese Academy of Sciences
2007
Institute of Zoology
2007
State Key Laboratory of Integrated Management of Pest Insects and Rodents
2007
Abstract The National Genomics Data Center (NGDC), part of the China for Bioinformation (CNCB), provides a suite database resources to support worldwide research activities in both academia and industry. With explosive growth multi-omics data, CNCB-NGDC is continually expanding, updating enriching its core through big data deposition, integration translation. In past year, considerable efforts have been devoted 2019nCoVR, newly established resource providing global landscape SARS-CoV-2...
Abstract On January 22, 2020, China National Center for Bioinformation (CNCB) released the 2019 Novel Coronavirus Resource (2019nCoVR), an open-access information resource severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). 2019nCoVR features a comprehensive integration of sequence and clinical all publicly available SARS-CoV-2 isolates, which are manually curated with value-added annotations quality evaluated by automated in-house pipeline. Of particular note, offers systematic...
Plants typically activate distinct defense pathways against various pathogens. Heightened resistance to one pathogen often coincides with increased susceptibility another pathogen. However, the underlying molecular basis of this antagonistic response remains unclear. Here, we demonstrate that mutants defective in transcription factor ETHYLENE-INSENSITIVE 3-LIKE 2 (OsEIL2) exhibited enhanced biotrophic bacterial Xanthomonas oryzae pv and hemibiotrophic fungal Magnaporthe oryzae, but...
The phylogenetic relationships among extant gibbon species remain unresolved despite numerous efforts using morphological, behavorial, and genetic data the sequencing of whole genomes. A major challenge in reconstructing phylogeny is radiative speciation process, which resulted extremely short internal branches extensive incomplete lineage sorting with gene-tree heterogeneity across genome. Here, we analyze two genomic-scale sets, ∼10,000 putative noncoding exonic loci, respectively, to...
Murine rodents are excellent models for study of adaptive radiations and speciation. Brown Norway rats (Rattus norvegicus) successful global colonizers the contributions their domesticated laboratory strains to biomedical research well established. To identify nucleotide-based speciation timing rat genomic information contributing its colonization capabilities, we analyzed 51 whole-genome sequences wild-derived sibling species, R. nitidus, identified over 20 million genetic variants in wild...
Abstract A novel RNA virus, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is responsible for ongoing outbreak of disease 2019 (COVID-19). Population genetic analysis could be useful investigating origin and evolutionary dynamics COVID-19. However, due to extensive sampling bias existence infection clusters during epidemic spread, direct applications existing approaches can lead biased parameter estimations data misinterpretation. In this study, we first present robust...
Abstract Since its discovery more than 110 years ago, Valsa canker has emerged as a devastating disease of apple in East Asia. However, our understanding this disease, particularly the identity causative agents, been state confusion. Here we provide synopsis for current and taxonomy causal agents. We highlight major changes concerning pathogens conflicting viewpoints moving to “One Fungus = One Name” system group fungal species. compiled list 21 Cytospora species associated with Malus hosts...
The aridification from Middle Miocene onwards has transformed the Asian interior into an arid environment, and Pleistocene glacial-interglacial oscillations exerted further ecological impact. Therefore, both glaciation would have considerably influenced evolution of many mid-latitude species in temperate Asia. Here, we tested this perspective by a phylogeographic study mesobuthid scorpions across Asia using one mitochondrial three nuclear genes. Concordant gene trees were obtained, which are...
The Asian house rat (AHR), Rattus tanezumi, has recently invaded the northern half of China. AHR is a highly adaptive species that also successfully conquered Qinghai-Tibet Plateau (QTP) and replaced brown (BR), R. norvegicus, at edge QTP. Here, we assembled draft genome explored mechanisms its northward invasion genetic basis underlying plateau adaptation in this species. Population genomic analyses revealed northwardly invasive AHRs consisted two independent genetically distinct...
Although Mesobuthus scorpions in China have become endangered recent years, they are largely underinvestigated. Even the baseline data on their distributions lacking. Here geographical of two provided through a combined study systematic field surveys and GIS-based ecological niche modeling using 227 surveyed point occurrence across an area ca. 2800 × 1700 km2 validated historical records. martensii (Karsch 1879) appears to be restricted latitude south 43°N north side Yangtze River, bordered...
Mycobacterium tuberculosis (M. tuberculosis) genotyping has dramatically improved the understanding of epidemiology (TB). In this study, 187 M. isolates from Xinjiang Uygur Autonomous Region (Xinjiang) and Gansu province in China were genotyped using large sequence polymorphisms (LSPs) variable number tandem repeats (VNTR). Ten isolates, which represent major nodes VNTR-based minimum spanning tree, selected subsequently subjected to multi-locus analyses (MLSA) that include 82 genes. Based on...
Abstract Background Invasive species bring a serious effect on local biodiversity, ecosystems, and even human health safety. Although the genetic signatures of historical range expansions have been explored in an array species, consequences contemporary received little attention, especially mammal species. In this study, we used whole-genome sequencing to explore rapid change introduction history newly invasive brown rat ( Rattus norvegicus ) population which invaded Xinjiang Province, China...
Many lacewing species (Insecta: Neuroptera) are important predators of pests with great potential in biological control. So far, there is no chromosome-level published genome available for Neuroptera. Here we report a high-quality reference green Chrysopa pallens (Neuroptera: Chrysopidae), which one the most insect natural enemies used pest biocontrol. The was sequenced using combination PacBio and Hi-C technologies assembled into seven chromosomes total size 517.21 Mb, occupying 96.07%...
Abstract Ancestry informative markers play an important role in medical genetics and forensic analyses. Several ancestry SNP panels have been developed validated that can differentiate global populations into continental or major regional groups. These served as good first‐tier genetic markers; however, their performance discriminating within regions appears unsatisfactory. To boost inference for populations, second‐tier with more refined discrimination power among subpopulations each of the...
Abstract Whole-genome sequencing of wild-derived rat species can provide novel genomic resources, which may help decipher the genetics underlying complex phenotypes. As a notorious pest, reservoir human pathogens, and colonizer, Asian house rat, Rattus tanezumi, is successfully adapted to its habitat. However, little known regarding genetic variation in this species. In study, we identified over 41,000,000 single-nucleotide polymorphisms, plus insertions deletions, through whole-genome...
Abstract Monolepta hieroglyphica (Motschulsky, 1858) has been recently revised as the synonym of M. signata (Oliver, 1808) based on morphological characteristics. quadriguttata 1860) was synonymized with over 100 years ago. However, this synonymy not be confirmed by molecular data. This widely distributed and abundant species shows a high variability in coloration patterns that caused numbers synonyms. We selected color forms typical for three nominal taxa phylogenetic analysis. The...
Clear knowledge about trophic interactions among species contributes to understanding biodiversity structuring and ecosystem functioning. However, identification of host-parasitoid is often impeded by the hyper-diversity parasitoid community their immature stages under study. As a consequence, our on rather incomplete many links are still missing. In this study, we discovered that scuttle fly Megaselia scalaris (Loew 1866) facultatively infested scorpions Mesobuthus eupeus mongolicus...
Abstract The black‐spotted pond frog Pelophylax nigromaculatus is a typical temperate‐adapted amphibian species, largely endemic to East Asia. It occurs from central, east, and northeast China, the Russian Far East, Korean Peninsula, part of Japan. So far, little known about this Loess Plateau, region that has experienced profound changes in climate environment since late Miocene. Particularly, between Plateau North China Plain, stand Lüliang Taihang mountain ranges, which form an important...
The family Erotylidae belongs to the superfamily Cucujoidea, which are phytophagous and mycophagous. So far, only two representative complete mitochondrial (mt) genomes of have been sequenced. Mitochondrial Tritoma metasobrina, Neotriplax arisana, Episcapha opaca, all belong subfamily Erotylinae, were sequenced using next-generation sequencing technology better understand diversity mt Erotylidae. A comparative genomic analysis was conducted on three representatives Erotylinae Languriinae sp....
Abstract On 22 January 2020, the National Genomics Data Center (NGDC), part of China for Bioinformation (CNCB), created 2019 Novel Coronavirus Resource (2019nCoVR), an open-access SARS-CoV-2 information resource. 2019nCoVR features a comprehensive integration sequence and clinical all publicly available isolates, which are manually curated with value-added annotations quality evaluated by our in-house automated pipeline. Of particular note, performs systematic analyses to generate dynamic...