A5103112713- Acute Myocardial Infarction Research
- Cardiac Imaging and Diagnostics
- Coronary Interventions and Diagnostics
- Cardiac, Anesthesia and Surgical Outcomes
- Pain Management and Placebo Effect
- Atrial Fibrillation Management and Outcomes
- Cardiac Structural Anomalies and Repair
- Lightning and Electromagnetic Phenomena
- Cardiac Arrhythmias and Treatments
- Cardiovascular Function and Risk Factors
- Fire effects on ecosystems
- Cardiac pacing and defibrillation studies
- Receptor Mechanisms and Signaling
- Meteorological Phenomena and Simulations
- Cardiac Arrest and Resuscitation
- Cardiac Valve Diseases and Treatments
- Health Systems, Economic Evaluations, Quality of Life
- Heart Rate Variability and Autonomic Control
- Venous Thromboembolism Diagnosis and Management
- Ultrasound in Clinical Applications
- Vascular Procedures and Complications
- Global Cancer Incidence and Screening
- Mechanical Circulatory Support Devices
- Pituitary Gland Disorders and Treatments
- Sepsis Diagnosis and Treatment
James Cook University Hospital
2004-2016
South Tees Hospitals NHS Foundation Trust
2001-2016
Department of Water
2015
3E (Belgium)
2013
Ghent University
2013
University of Florida
1987-2011
Michigan Medicine
2011
British Cardiovascular Society
2010
University of Otago
2006-2007
Center Orthopedic & Neurosurgical Care & Research
2007
We determined the relative contribution of beta 1- and 2-adrenoceptor stimulation to positive inotropic responses human atrial myocardium catecholamines. (-)Norepinephrine produced predominantly through 1-receptors (-)epinephrine both 2-receptors. However, there were marked differences in tissues from patients treated with 1-selective antagonist atenolol compared non-beta-blocker-treated patients; surprisingly, 2-mediated enhanced, 1-mediated unaltered. There was an enhanced responsiveness...
<h3>Objective:</h3> To examine the safety and efficacy of emergency transradial primary percutaneous coronary intervention for ST-elevation myocardial infarction. <h3>Design:</h3> Single-centre observational study with prospective data collection. <h3>Setting:</h3> A regional cardiac centre, United Kingdom. <h3>Patients:</h3> 1051 consecutive patients admitted infarction, without cardiogenic shock, between November 2004 October 2008. <h3>Interventions:</h3> Percutaneous interventions by...
Journal Article A comparison of the effects adrenaline and noradrenaline on human heart: role β1- β2-adrenoceptors in stimulation adenylate cyclase contractile force Get access A. J. Kaumann, Kaumann *Smith Kline & French Research LimitedWelwyn, Hertfordshire†Clinical Pharmacological Unit, Addenbrooke's HospitalCambridge Address for correspondence: Dr Smith Ltd, The Frythe, Welwyn, Hertfordshire AL6 9AR, U.K. Search other works by this author on: Oxford Academic PubMed Google Scholar Hall,...
ABSTRACT Background: Conventional implant protocols advocate a two‐stage technique with load‐free, submerged healing period. Recent studies suggest that immediate restoration of single implants may be viable treatment option. Purpose: The purpose this study was to evaluate prosthodontic and aesthetic peri‐implant mucosal outcomes immediately restored, Southern single‐tapered in the anterior maxilla after 1 year. Materials Methods: Participants (mean age: 43.25 years; range: 23–71 years)...
The previous Core Curriculum for the General Cardiologist defined a model cardiology training in Europe and it has been adopted as standard regulating training, access to specialty (certification), revalidation several countries.1 During last 5 years we have witnessed profound changes cardiological practice. work of both hospital independent cardiologists better integrated with that general practitioners. It taken into account requirements national authorities, re-imbursement organizations,...
To demonstrate the presence of functional cardiac beta 2-adrenoceptors in man, we studied responses to intracoronary injections salbutamol three groups six patients. We injected salbutamol, a selective 2-adrenoceptor agonist, into right coronary artery avoid peripheral vasodilator action and stimulate sinoatrial node directly. Salbutamol caused sinus tachycardia. The same doses aortic root no change heart rate, ruling out systemic effect. mean dose required cause an increase rate 30...
To compare the quality of outpatient anticoagulant control before and after transfer dosing responsibility to designated trained pharmacists from rotating junior medical staff.All International Normalised Ratio (INR) values for an eight month period either side staff changeover were assessed precision therapeutic according described standards. Allowing patient associated effects, observed expected frequencies "successful" two groups compared under hypothesis no association.INR results (n =...
Treatment with beta 1-selective antagonists causes selective sensitization of isolated strips human atrial myocardium to the inotropic action epinephrine and 2-agonists but not norepinephrine. To determine whether antagonist treatment alters responsiveness cardiac 2-adrenoreceptors in vivo, we measured positive chronotropic responses salbutamol injected into right coronary artery. Ten patients treated atenolol (50-100 mg daily) were compared 10 beta-blockers. The mean dose required cause an...
Regional cerebral blood flow was simultaneously determined using the stable xenon computed tomographic and radioactive microsphere techniques over a wide range of rates (less than 10-greater 300 ml/100 g/min) in 12 baboons under conditions normocapnia, hypocapnia, hypercapnia. A total 31 pairs determinations were made. After anesthetic surgical preparation baboons, repeatedly technique during saturation with 50% oxygen. Concurrently, before administration 15-microns microspheres. In Group 1...
<b>Objective</b> To use funnel plots and cumulative to compare in-hospital outcome data for operators undertaking percutaneous coronary interventions with predicted results derived from a validated risk score allow early detection of variation in performance. <b>Design</b> Analysis prospectively collected data. <b>Setting</b> Tertiary centre NHS hospital the north east England. <b>Participants</b> Five cardiologists carrying out between January 2003 December 2006. <b>Main measures</b>...
Abstract A case of T-1, T-2 disc herniation is reported. The patient presented with diminished hand strength, medial arm and shoulder pain, arm, forearm, paresthesias. After surgical decompression removal a fragment, the made complete recovery. Routine cervical myelography was considered inadequate in view this patient's symptoms. High thoracic followed by computed tomographic scanning should be for patients presentation. Improved diagnosis tomography discussed.