- Monoclonal and Polyclonal Antibodies Research
- Forest Biomass Utilization and Management
- Hematopoietic Stem Cell Transplantation
- Advanced Biosensing Techniques and Applications
- Angiogenesis and VEGF in Cancer
- dental development and anomalies
- Biochemical and Molecular Research
- Click Chemistry and Applications
- Soil Mechanics and Vehicle Dynamics
- Tree Root and Stability Studies
- Oral and Maxillofacial Pathology
- Blood groups and transfusion
- RNA Interference and Gene Delivery
- T-cell and B-cell Immunology
- Computational Drug Discovery Methods
- Platelet Disorders and Treatments
- Immunotherapy and Immune Responses
- Forest Management and Policy
- Blood transfusion and management
- Forest ecology and management
- Bone and Dental Protein Studies
CSIRO Manufacturing
2013-2019
Australian Regenerative Medicine Institute
2017-2019
Monash University
2017-2019
Commonwealth Scientific and Industrial Research Organisation
2014
Materials Science & Engineering
2013
Stem Cells Australia
2009
Background: The success of clinical hematopoietic stem cell (HSC) transplants is highly dependent on the ability HSC to home bone marrow (BM). Although it appreciated that recovery post-transplant correlated infused number, greater understanding homing mechanisms should allow us identify improved transplant strategies are not solely reliant number but also quality. Mobilized blood most common source for and gold standard mobilization agent, granulocyte-colony stimulating factor (G-CSF),...
Abstract The expression and activity of the Myc oncoprotein is frequently dysregulated in human cancers due to amplification, translocation, protein stabilization and/or convergence oncogenic signaling pathways on Myc. Therapeutic inhibition highly desirable however, prior efforts identify specific direct pharmacological inhibitors function have generally failed yield Myc-selective drug-like small molecules. Herein, we comprehensively profiled previously reported molecule Myc-Max...