- Bacterial Genetics and Biotechnology
- Bacterial biofilms and quorum sensing
- Genetics, Aging, and Longevity in Model Organisms
- Plant and animal studies
- Evolution and Genetic Dynamics
- RNA and protein synthesis mechanisms
- CRISPR and Genetic Engineering
- Microbial Metabolic Engineering and Bioproduction
- Evolutionary Game Theory and Cooperation
- Algal biology and biofuel production
- Vibrio bacteria research studies
- Gut microbiota and health
- Anaerobic Digestion and Biogas Production
- Microbial Fuel Cells and Bioremediation
MRC London Institute of Medical Sciences
2021-2022
Hammersmith Hospital
2021-2022
Imperial College London
2021-2022
Institut de Microbiologie de la Méditerranée
2020-2021
Aix-Marseille Université
2020-2021
Centre National de la Recherche Scientifique
2020-2021
Loss of proteostasis is a fundamental process driving aging. Proteostasis affected by the accuracy translation, yet physiological consequence having fewer protein synthesis errors during multi-cellular organismal aging poorly understood. Our phylogenetic analysis RPS23, key in ribosomal decoding center, uncovered lysine residue almost universally conserved across all domains life, which replaced an arginine small number hyperthermophilic archaea. When introduced into eukaryotic RPS23...
Formation of multispecies communities allows nearly every niche on earth to be colonized, and the exchange molecular information among neighboring bacteria in such is key for bacterial success. To clarify principles controlling interspecies interactions, we previously developed a coculture model with two anaerobic bacteria,
Abstract To clarify the principles controlling inter-species interactions, we previously developed a co-culture model with two anaerobic bacteria, Clostridium acetobutylicum and Desulfovibrio vulgaris Hildenborough, in which nutritional stress for D. induced tight cell-cell interaction. Here show that exchange of metabolites produced by C. allows to duplicate its DNA, be energetically viable even without substrates. Physical interaction between (or Escherichia coli ) is linked quorum-sensing...