A5041219898- Advanced Photonic Communication Systems
- Advanced Fiber Laser Technologies
- Optical Network Technologies
- Advanced Optical Sensing Technologies
- Electromagnetic wave absorption materials
- Cancer Immunotherapy and Biomarkers
- Immunotherapy and Immune Responses
- Thermal properties of materials
- Advanced Frequency and Time Standards
- Immune Cell Function and Interaction
- Immune cells in cancer
- Advanced Antenna and Metasurface Technologies
- Dielectric materials and actuators
- Semiconductor Lasers and Optical Devices
- Photonic and Optical Devices
- Nanoplatforms for cancer theranostics
- Thermal Radiation and Cooling Technologies
- Land Use and Ecosystem Services
- Epigenetics and DNA Methylation
- Pregnancy and preeclampsia studies
- Ferroptosis and cancer prognosis
- Alzheimer's disease research and treatments
- RNA Interference and Gene Delivery
- Smart Grid Energy Management
- Metal-Catalyzed Oxygenation Mechanisms
Northwest A&F University
2019-2025
Qingdao University of Science and Technology
2023-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2013-2024
Zhengzhou University
2021-2024
China Pharmaceutical University
2004-2024
East China University of Science and Technology
2024
Suqian University
2024
Zhejiang Medicine (China)
2024
Harvard University
2023-2024
Chinese Academy of Sciences
2019-2023
Abstract With the innovation of microelectronics technology, heat dissipation problem inside device will face a severe test. In this work, cellulose aerogel (CA) with highly enhanced thermal conductivity (TC) in vertical planes was successfully obtained by constructing vertically aligned silicon carbide nanowires (SiC NWs)/boron nitride (BN) network via ice template-assisted strategy. The unique structure SiC NWs connected to BN ensures that TC composite direction reaches 2.21 W m −1 K at...
The high redox level of tumor microenvironment inhibits the oxidation treatment and immune response. Here, we innovatively develop maleimide liposome (ML) adjuvants to promote immunogenic cell death (ICD) induction dendritic cells (DCs) maturation by glutathione (GSH) depletion for augmenting photothermal immunotherapy breast cancer. ML effectively depletes intracellular GSH up-regulates reactive oxygen species (ROS) in both DCs. In cells, ROS boosted ABTS·+ production activate...
Programmed cell death-1 (PD-1)/programmed death ligand-1 (PD-L1) blocking therapy has become a major pillar of cancer immunotherapy. Compared with antibodies targeting, small-molecule checkpoint inhibitors which have favorable pharmacokinetics are urgently needed. Here we identified berberine (BBR), proven anti-inflammation drug, as negative regulator PD-L1 from set traditional Chinese medicine (TCM) chemical monomers. BBR enhanced the sensitivity tumour cells to co-cultured T-cells by...
Stretchability and multifunctional heating abilities are highly desired for wearable electromagnetic interference (EMI) shielding fabrics to tackle the growing pollution special crowd, such as pregnant women. Herein, we fabricated stretchable MXene-coated thermoplastic polyurethane (TPU) by simple uniaxial prestretching spraying methods. The obtained unique wrinkled structure endowed film with effective strain-invariant electrical conductivity EMI properties. Specifically, prepared an...
The abundant glutathione (GSH) in "cold" tumors weakens ferroptosis therapy and the immune response. Inspired by lipids, we fabricated cinnamaldehyde dimers (CDC) into lipid-like materials to form dimersomes capable of depleting GSH delivering therapeutics potentiate immunotherapy breast cancer. exhibited superior storage stability for over one year. After reaching tumor, they quickly underwent breakage cytosol owing conjugation hydrophilic on CDC Michael addition, which not only triggered...
Abstract Electromagnetic interference (EMI) shielding fabrics are crucial in addressing the increasingly serious electromagnetic pollution. To meet wearable requirements, stretchability and thermal comfortability often desired, but which still challenging. Herein, a stretchable EMI fabric is fabricated via electrospinning coupled with biaxial pre‐stretching spraying, block stacking wrinkled silver nanowire (AgNW)/Ti 3 C 2 T x MXene network coated on one side of electrospun thermoplastic...
Abstract Transparent electromagnetic interference (EMI) shielding is highly desired in specific visual scenes, but the challenge remains balancing their EMI effectiveness (SE) and optical transmittance. Herein, this study proposed a directionally aligned silver nanowire (AgNW) network construction strategy to address requirement of high SE satisfactory light transmittance using rotation spraying technique. The orientation distribution AgNW induced by centrifugal inertia force generated...
Programmed cell death ligand 1 (PD-L1)/programmed protein (PD-1) cascade is an effective therapeutic target for immune checkpoint blockade (ICB) therapy. Targeting PD-L1/PD-1 axis by small-molecule drug attractive approach to enhance antitumor immunity. Using flow cytometry-based assay, we identify tubeimoside-1 (TBM-1) as a promising modulator that negatively regulates PD-L1 level. TBM-1 disrupts PD-1/PD-L1 interaction and enhances the cytotoxicity of T cells toward cancer through...
Abstract Immune checkpoint therapies (ICT) have achieved unprecedented efficacy in multiple cancer treatments, but are still limited by low clinical response rates. Identification of immunogenic cell death (ICD)‐inducing drugs that can induce tumor immunogenicity and reprogram the microenvironment is an attractive approach to enhance antitumor immunity. In present study, Raddeanin A (RA), oleanane class triterpenoid saponin isolated from Anemone raddeana Regel , uncovered as a potent ICD...
Existing antibody-drug conjugate (ADC) linkers, whether cleavable or non-cleavable, are designed to release highly toxic payloads payload derivatives upon internalisation of the ADCs into cells. However, clinical studies have shown that only <1 % dosed accumulate in tumour The remaining >99 nonspecifically distributed healthy tissue cells, thus inevitably leading off-target toxicity. Herein, we describe an intelligent tumour-specific linker strategy address these limitations. A is...
Abstract The Square Kilometre Array (SKA) project is an international effort to build the world’s largest radio telescope, with a one-square-kilometre collecting area. In addition its ambitious scientific objectives, such as probing cosmic dawn and cradle of life, SKA demands several revolutionary technological breakthroughs, ultra-high precision synchronisation frequency references for thousands antennas. this report, purpose application SKA, we demonstrate reference dissemination scheme in...
The scaled-up synthesis of organic-free monolayer nanomaterials is highly desirable, especially in obtaining green energy by electrocatalysis. In this study, a method for the series layered double hydroxides (LDHs) without addition organic solvents reported via separate nucleation and aging steps process. resulting LDHs with thicknesses less than 1 nm showed narrow thickness distribution. X-ray absorption fine-structure revealed that NiFe-LDH nanosheets have number oxygen metal vacancies...
Pt<sub>84</sub>Pb<sub>16</sub>bimetallic alloy nanoflowers were synthesized by a simple hydrothermal method and exhibit an enhanced catalytic activity towards formic acid electrooxidation.