A5086007661- Spondyloarthritis Studies and Treatments
- Autoimmune and Inflammatory Disorders Research
- Psoriasis: Treatment and Pathogenesis
- Rheumatoid Arthritis Research and Therapies
- Cardiac Valve Diseases and Treatments
- Colorectal Cancer Treatments and Studies
- Cancer Genomics and Diagnostics
- Aortic Disease and Treatment Approaches
- Inflammasome and immune disorders
- Cancer Immunotherapy and Biomarkers
- Immunodeficiency and Autoimmune Disorders
- Cardiovascular Function and Risk Factors
- Respiratory Support and Mechanisms
- Mechanical Circulatory Support Devices
- Prostate Cancer Treatment and Research
- T-cell and B-cell Immunology
- Systemic Lupus Erythematosus Research
- Inflammatory Myopathies and Dermatomyositis
- Autoimmune Bullous Skin Diseases
- Diet and metabolism studies
- Cardiac Arrhythmias and Treatments
- Cytokine Signaling Pathways and Interactions
- Osteoarthritis Treatment and Mechanisms
- Vasculitis and related conditions
- Orthopedic Infections and Treatments
Hebron University
2024
Center for Rheumatology
2024
IrsiCaixa
2021
Hospital Clínico Universitario de Caracas
2013-2021
Hospital Universitario Puerta de Hierro Majadahonda
2016-2021
Universitat Autònoma de Barcelona
2018
Complejo Hospitalario Universitario de Granada
2017-2018
Universidad de Salamanca
2017
Centro de Investigación del Cáncer
2017
Instituto de Investigación Biomédica de Salamanca
2017
Objective Psoriatic arthritis (PsA) is chronic disease that compromises multiple domains and might be associated with progressive joint damage, increased mortality, functional limitation, considerably impaired quality of life. Our objective was to generate evidence-based recommendations on the management PsA in Pan American League Associations for Rheumatology (PANLAR) countries. Methods We used Grading Recommendations, Assessment, Development, Evaluation (GRADE)-ADOLOPMENT approach adapt...
Abstract The 2019 coronavirus (COVID-19) can generate acute respiratory distress syndrome (ARDS), requiring advanced management within the Intensive Care Unit (ICU) using invasive mechanical ventilation (IMV However, managing this phenomenon has seen learning and improvements through direct experience. Therefore, study aims were to describe assessment of different IMV variables in patients with post-COVID-19 hospitalized ICU their relation mortality. Observational retrospective study. sample...
We studied 75 patients with a mean age of 36 years, who were injected modeling substances and developed untoward side effects. About 75% the responded to deflazacort + colchicine; however, 92% suffered relapse five months later received azathioprine as immunosuppressant. The most frequent clinical manifestations were: erythema 90%, skin pigmentation 58%, edema 70% keloids 25%. There also autoimmune such Raynaud's phenomenon, livedo reticularis, psoriasis arthritis. have designed treatment...
Abstract Objective Our aim was to describe a new right-heart failure (RHF) staging system in patients with severe tricuspid regurgitation (TR). Methods Multicenter, observational, and prospective registry which all TR have been consecutively collected within 6-month period, classified according their clinical condition right ventricular status, followed up for one year. Results A total of 1247 [mean age: 76.7±10.5 years, 876 women (70.2%)] were included: 810 (64.9%) met criteria TR, 301...
Abstract Objective Our aim was to assess the prognostic role of etiology tricuspid valve disease in patients with severe regurgitation (TR). Methods Multicenter, observational, and prospective registry which all TR have been consecutively collected within a 6-month period followed up for one year. Results A total 1247 [mean age: 76.7±10.5 years, 876 women (70.2%)] were included: 810 (64.9%) met criteria TR, 301 (24.1%) massive 136 (11%) torrential TR. The most frequent functional secondary...
Infl ammatory Bowel Disease (IBD)-associated arthritis is called Enteropathic Arthritis (EA) which classifi ed among the group of Spondyloarthritis (SpA), because its presentation variable.The current trend to classify them as autoinfl rather than autoimmune diseases, since no antibodies have yet been identifi ed.The study biomarkers (BM) will help us with early cation and hence, provide treatment in stages, prior radiographic progression, enable prompt disease phenotype.42 patients...
<h3>Background</h3> Gliptins are indicated for diabetes mellitus type-2 (DM-II). They inhibit dipeptidyl peptidase IV (DPP-IV), an enzyme which is responsible deterioration of incretin hormones. increase insulemic secretion in manner glucose dependent, therefore they have positive effects glycaemic control. Several cases bullous pemphigoid (BP) been described since came on the market. Epidermal keratinocytes DPP-IV, consequently a possible mechanism implied pathogenesis BP derived from...
Objective: Ascending aorta (AAo) dilation is highly prevalent in bicuspid aortic valve (BAV) patients. The etiology of BAV patients widely discussed, with strong evidence for a role both altered local hemodynamics (due to morphology), and genetic factors. Current guidelines suggest use threshold AAo diameter the indication prophylactic resection. Nonetheless, as 40 % dissection happen non-dilated or mildly-dilated aorta, there clear need new biomarkers. We aim investigate whether regional...
Objectives: Our aim was to compare an AntiCD20 therapy (rituximab) for rheumatoid arthritis in two patient populations (Group 1), anti-TNFα naïve patients and inadequate responders Anti-TNFα 2). Methods: We analyzed the efficacy of drug Rituximab (RTX) RA who failed methotrexate (MTX) or had a relative absolute contraindication receive therapy. Results: 25 were identified according above criteria followed up mean period 6 months. Thirteen biologic twelve already Group 1 used 2> DMARDs...