A5024347949- Intraperitoneal and Appendiceal Malignancies
- Appendicitis Diagnosis and Management
- Gallbladder and Bile Duct Disorders
- Dialysis and Renal Disease Management
- Ovarian cancer diagnosis and treatment
- Pancreatic and Hepatic Oncology Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Dysphagia Assessment and Management
- Esophageal and GI Pathology
- Hepatocellular Carcinoma Treatment and Prognosis
- Birth, Development, and Health
- Chronic Kidney Disease and Diabetes
- Acute Myocardial Infarction Research
- Colorectal Cancer Treatments and Studies
- Anesthesia and Pain Management
- Pancreatitis Pathology and Treatment
- Cancer survivorship and care
- Palliative Care and End-of-Life Issues
- Cardiac, Anesthesia and Surgical Outcomes
- Gastroesophageal reflux and treatments
- Central Venous Catheters and Hemodialysis
- Diabetes Management and Research
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Congenital Anomalies and Fetal Surgery
- Childhood Cancer Survivors' Quality of Life
Atrium Health Wake Forest Baptist
2013-2025
Wake Forest University
2016-2025
Wake Forest Baptist Comprehensive Cancer Center
2023
Lexington VA Health Care System
2022
University of Michigan
2022
University of Kentucky
2022
Portland State University
2018
Mississippi State University
2018
University of Alabama
2018
Biostatistical Consulting (United States)
2010-2018
Background— The HEART Pathway is a decision aid designed to identify emergency department patients with acute chest pain for early discharge. No randomized trials have compared the usual care. Methods and Results— Adult symptoms related coronary syndrome without ST-elevation on ECG (n=282) were or In arm, providers used score, validated aid, troponin measures at 0 3 hours Usual care was based American College of Cardiology/American Heart Association guidelines. primary outcome, objective...
Pseudomyxoma peritonei is a clinical term for gelatinous ascites, usually secondary to an appendiceal tumor. The pathologic classification of pseudomyxoma and its associated tumors has been plagued with controversy confusing terminology. In effort clarify this, we reviewed the pathology 101 patients, all treated at our institution from 1993 2005, origin. All patients were uniformly standardized protocol. This largest series solely devoted neoplasia ascites. cases assigned, according...
Restorative yoga (RY) is a gentle type of that may be beneficial for cancer patients and post-treatment survivors. Study goals were: to determine the feasibility implementing RY intervention women with breast cancer; examine group differences in self-reported emotional, health-related quality life, symptom outcomes.
Background and objectives Relative to hemoglobin (Hb) A1c, glycated albumin (GA) more accurately reflects glycemic control in patients with diabetes mellitus ESRD. We determined the association between GA, HbA1c, glucose levels survival hospitalizations diabetic dialysis patients. Design, setting, participants, & measurements Quarterly GA were measured for up 2.33 years 444 prevalent Proportional hazard time-dependent covariate models computed adjustment demographic characteristics,...
Increased advanced glycation end products (AGEs) and oxidation (OPs) are proposed to lead progression of diabetic nephropathy (DN). We investigated the relationship between AGEs, OPs, DN in 103 subjects with type 1 diabetes participating Natural History Diabetic Nephropathy Study.Mean age was 17.6±7.4 years, mean duration 8.3±4.9 years. All patients were normoalbuminuric. Change glomerular basement membrane (GBM) width from baseline 5 measured using electron micrographs renal biopsies, our...
The purpose of this study was to elicit preferences for the treatment metastatic breast cancer in women with early-stage who were given hypothetical scenarios. We predicted that quality life, demographic, and variables would have an impact on patient preferences.One hundred fifteen patients stage 1-IIIA interviewed. All had either mastectomy or lumpectomy plus radiotherapy as primary treatment. Sixty-seven (58%) prior adjuvant chemotherapy. Patients four clinical scenarios described a woman...
No standard effective treatment exists for peritoneal carcinomatosis of gastrointestinal origin. The pharmacokinetic advantage intraperitoneal chemotherapy and the synergy heat certain anticancer agents have prompted researchers to investigate hyperthermic in treating disseminated cancers. We conducted a large Phase II trial determine safety efficacy aggressive cytoreductive surgery (IPHC) Patients with origin or without malignant ascites were eligible. After surgical debulking, patients...
Purpose The purpose of this study was to determine the effects trial (i.e., Trial 1 vs. 2); viscosity saliva, thin, nectar-thick, honey-thick, and pudding-thick water); volume 5 mL 10 mL); age young older adults); gender on pharyngeal upper lower) esophageal sphincter (UES) pressures, durations, onsets onset pressures relative UES relaxations lower pressures). Method Twenty-three adults ( M = 30 years) 21 healthy 75 participated. Measurements were acquired with a 2.1-mm catheter during...
Background Relative to hemoglobin A 1c (HbA ), percentage of glycated albumin (GA%) more accurately reflects recent glycemic control in diabetic hemodialysis (HD) patients. Methods To determine the accuracy assays a larger sample including patients on peritoneal dialysis (PD), HbA and GA% were measured 519 subjects: 55 PD, 415 HD, 49 non-nephropathy controls. Results Mean ± SD serum glucose levels higher HD PD relative controls (HD 169.7 62 mg/dL, 168.6 66 146.1 mg/dL; p = 0.03 vs controls,...
Yin Yang 1 (YY1) is highly expressed in various types of cancers and regulates tumorigenesis through multiple pathways. In the present study, we evaluated YY1 expression levels breast cancer cell lines, a TMA, two gene arrays. We observed that, compared with normal samples, generally overexpressed cells tissues. functional studies, depletion inhibited clonogenicity, migration, invasion, tumor formation cells, but did not affect clonogenicity nontumorigenic cells. Conversely, ectopically...
Background. The efficacy of barrier precautions to prevent influenza transmission is unknown. Methods. Twenty-eight participants were exposed monodispersed live attenuated vaccine (LAIV) particles (4.9 μm) in 6 groups: group 1, no precautions; 2, ocular exposure only; 3, surgical mask without eye protection; 4, with 5, fit-tested N95 respirator and 6, protection. Influenza was detected by reverse-transcription polymerase chain reaction (RT-PCR) culture nasal washes. Exact 95% confidence...
<i>Background:</i> Relative to hemoglobin A<sub>1c</sub> (HbA<sub>1c</sub>), glycated albumin (GA) more accurately reflects recent glycemic control in diabetic patients on hemodialysis and peritoneal dialysis. These assays have yet be compared with advanced chronic kidney disease (CKD). <i>Methods:</i> HbA<sub>1c</sub> GA were simultaneously measured 303 subjects: 70 CKD prior dialysis (CKD-stage 4), 184 after transplantation...