Julian Frederic Hotz

ORCID: 0000-0003-0270-790X
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About
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Research Areas
  • Parasitic infections in humans and animals
  • Parasitic Infections and Diagnostics
  • Congenital Anomalies and Fetal Surgery
  • Antimicrobial Resistance in Staphylococcus
  • Amoebic Infections and Treatments
  • Bacteriophages and microbial interactions
  • Plant Pathogenic Bacteria Studies
  • Bacillus and Francisella bacterial research
  • Plant-Microbe Interactions and Immunity
  • Urinary and Genital Oncology Studies
  • Urological Disorders and Treatments

Medical University of Vienna
2022-2024

University Hospital Ulm
2022-2023

Human alveolar echinococcosis (AE), which is caused by the cestode Echinococcus (E.) multilocularis, an epidemiologically relevant issue in modern medicine and still poses a diagnostic therapeutic challenge. Since diagnosis mainly relies on imaging procedures serological testing, we retrospectively comparatively analyzed performance of IgG screening ELISA, whole serum IgE, two specific confirmatory ELISA platforms using defined E. multilocularis antigens Em2-Em18 (Em2+) recombinant Em18...

10.3390/pathogens11020239 article EN cc-by Pathogens 2022-02-12

The increasing prevalence of methicillin-resistant Staphylococcus aureus (MRSA) strains resistant to non-beta-lactam antimicrobials poses a significant challenge in treating severe MRSA bloodstream infections. This study explores resistance development and mechanisms isolates, especially after the first dalbavancin-resistant strain our hospital 2016. investigated 55 isolates (02/2015–02/2021) from University Hospital Medical Vienna, Austria. MICs dalbavancin, linezolid, daptomycin were...

10.1186/s12879-024-09797-w article EN cc-by-nc-nd BMC Infectious Diseases 2024-09-02

Invasive Staphylococcus aureus infections are associated with a high burden of disease, case fatality rate and healthcare costs. Oxazolidinones such as linezolid tedizolid considered potential treatment choices for conditions involving methicillin resistance or penicillin allergies. Additionally, they being investigated inhibitors toxins in toxin-mediated diseases. In this study, were evaluated an vitro development model induction S. aureus. Whole genome sequencing was conducted to elucidate...

10.1080/22221751.2023.2292077 article EN cc-by-nc Emerging Microbes & Infections 2023-12-06

IntroductionRecurrence after curative resection of hepatic alveolar echinococcosis remains a clinical challenge. The current study tested if assessment anti-recEm18 allows for postsurgical patient surveillance in patients undergoing radical echinococcosis.MethodsA retrospective with liver (n = 88) at the University Hospital Bern from 2002 to 2020 and Medical Center Ulm 2011 2017 was performed. Analysis directed determine potential association pre- postoperative values...

10.1016/j.hpb.2023.10.007 article EN cc-by HPB 2023-10-10

Abstract Purpose: The increasing prevalence of methicillin-resistant Staphylococcus aureus (MRSA) strains resistant to non-beta-lactam antimicrobials poses a significant challenge in treating severe MRSA bloodstream infections. This study explores resistance development and mechanisms isolates, especially after the first dalbavancin-resistant strain our hospital 2016. Methods: investigated 55 isolates (02/2015–02/2021) from University Hospital Medical Vienna, Austria. MICs dalbavancin,...

10.21203/rs.3.rs-3951551/v1 preprint EN cc-by Research Square (Research Square) 2024-02-14

Echinococcosis is caused by an infection with a tapeworm's larval stage of the genus Echinococcus (E.). Humans, who are accidental intermediate hosts to these parasites become infected ingesting ova from carnivorous definite hosts. In contrast devastating disease alveolar echinococcosis (AE), E. multilocularis, granulosus sensu lato (cystic (CE)) typically causes chronic disease, which can be asymptomatic for decades, depending on size, location and number cysts (Brunetti E et al., Acta Trop...

10.1055/a-2417-6711 article EN Klinische Pädiatrie 2024-10-15

Echinococcosis is a neglected zoonotic disease and worldwide public health problem caused by infection with the larval stages of taeniid cestodes genus Echinococcus. In vitro studies have demonstrated protoscolecidal effect eosinophilic cationic protein (ECP), granule granulocytes, against E. granulosus. Therefore, main objective this study was to evaluate ECP as biomarker in treatment alveolar echinococcosis (AE) cystic (CE). Data were collected retrospectively from Vienna Cohort over 7...

10.3390/pathogens11020261 article EN cc-by Pathogens 2022-02-18

Abstract Background Best monitoring practices for patients after resection of hepatic alveolar echinococcosis remain unclear. Aims The current study tested if assessment anti-recEm18 allows postsurgical patient surveillance. Methods A retrospective with undergoing liver at the University Hospital Berne from December 2002 to 2020 and Medical Center Ulm January 2011 2017 was performed. Analysis directed determine a potential association pre- postoperative values clinical outcomes. Results...

10.1093/bjs/znad178.012 article EN British journal of surgery 2023-06-01
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