- Microbial Natural Products and Biosynthesis
- Glaucoma and retinal disorders
- Retinal Diseases and Treatments
- Fungal Biology and Applications
- Vascular Malformations Diagnosis and Treatment
- Genomics and Phylogenetic Studies
- Intracranial Aneurysms: Treatment and Complications
- Intraocular Surgery and Lenses
- Intracerebral and Subarachnoid Hemorrhage Research
- Plant Pathogens and Fungal Diseases
- Plant-Microbe Interactions and Immunity
- Connexins and lens biology
- Infectious Diseases and Tuberculosis
- Glioma Diagnosis and Treatment
- Moyamoya disease diagnosis and treatment
- Retinal and Macular Surgery
- Synthesis of Organic Compounds
- Actinomycetales infections and treatment
- Retinal and Optic Conditions
- Immune Response and Inflammation
- Spinal Dysraphism and Malformations
- Ocular Diseases and Behçet’s Syndrome
- NF-κB Signaling Pathways
- Ophthalmology and Visual Impairment Studies
- Plant biochemistry and biosynthesis
West China Hospital of Sichuan University
2016-2024
Sichuan University
2016-2024
Nanjing Drum Tower Hospital
2021-2022
Sun Yat-sen Memorial Hospital
2018-2020
Sun Yat-sen University
2018-2020
University of Chinese Academy of Sciences
2013
South China Sea Institute Of Oceanology
2005-2012
Institute of Oceanology
2005-2012
Chinese Academy of Sciences
2005-2012
Endophytic actinobacteria colonize internal tissues of their host plants and are considered as a rich reliable source diverse species functional microorganisms. In this study, endophytic actinobacterial strain YIM 63111 was isolated from surface-sterilized tissue the medicinal plant Artemisia annua. We identified member genus Pseudonocardia. A. annua seedlings grown under both sterile greenhouse conditions were inoculated with 63111. The growth strongly reduced when at higher concentrations...
Three filamentous actinomycetes, strains YIM 65594 T , 65638 and 65642, were isolated from the surface-sterilized roots of Artemisia annua L. collected Yunnan province, south-west China. These found to have morphological chemotaxonomic characteristics typical genus Streptomyces . The organisms formed an extensively branched substrate mycelium, with abundant aerial hyphae that differentiated into spores. cell wall isolates contained ll -diaminopimelic acid menaquinones MK-9(H 8 ) 6 ). major...
A novel endophytic actinomycete, strain YIM 65646 T , was isolated from the roots of Artemisia annua L. collected Yunnan Province, south-west China. Growth observed in temperature range 10–40 °C (optimum 20–28 °C) and at pH 6.0–9.0 7.0). The organism formed well-developed, branched substrate mycelia, but aerial mycelium not produced. Phenotypic characterization 16S rRNA gene sequence analysis indicated that belonged to family Micromonosporaceae (sharing ≤93.6 % similarity with members this...
A 27-year-old man was admitted to our hospital for a 1-week history of acute bilateral upper limbs weakness, pain, and numbness. Those symptoms progressively aggravated in short period, were accompanied with urinary retention constipation. Physical examination showed decreased sensation the prechest abdomen, meningeal irritation sign negative. Medical revealed he received acupuncture his cervical pain local clinic. Cervicothoracic spinal magnetic resonance imaging an intramedullary lesion...
The role of the IκB/NF-κB signaling pathway in uveoscleral outflow was investigated with IκBα gene silencing mediated by 3-(dimethylamino)-1-propylamine-conjugated glycogen (DMAPA-Glyp) derivative. IκBα-siRNA-loaded DMAPA-Glyp complex transfected into ciliary muscles rats intracameral injection (labeled as DMAPA-Glyp+siRNA group). Lipofectamine™ 2000 (Lipo)/siRNA and naked siRNA were set controls. mRNA protein expression IκBα, NF-κBp65, MMP-2 analyzed real-time PCR, western blotting, situ...
To observe the long-term clinical efficacy of intravitreal injections conbercept, a novel vascular growth factor inhibitor, for treatment pathological myopia choroidal neovascularization (PM-CNV).A total 67 eyes (from patients; mean age, 54.90±12.7y) with PM-CNV were retrospectively researched. Based on different schemes used administration drug, patients divided into two groups: group A (n=35; average 53.31±13.6y; diopter, 9.25±1.72 D), which received only one injection pro re nata (PRN;...
Ten phenylpiperazine derivatives were designed and synthesized. The first complete assignments of 1H 13C NMR chemical shifts for these achieved by means 1D 2D techniques, including 1H–1H COSY, HSQC HMBC spectra. Copyright © 2005 John Wiley & Sons, Ltd.
Purpose: To investigate the effects of indocyanine green (ICG) solution on viability and cytolysis human lens epithelial cells ex vivo. Methods: A total 200 pieces anterior capsules were obtained during cataract surgery, 110 randomly divided into five groups treated by immersion in different concentrations ICG solution. The remaining 90 also with a combination drug washing balanced salt Electron microscopy trypan blue eosin stains used to analyze cells. Percentage dead, shedding, or living...