Hyperventilation will cause vertigo, spasm, loss of consciousness etc., which seriously affects flight safety. For pilots, it is not easy to distinguish between hyperventilation and hypoxia. In this paper, a real-time trend monitoring algorithm in-flight proposed help pilot judge prevent hyperventilation. Firstly, we propose RP pressure instead mask de-noise, respiratory rate validity eliminate breathing state with very low signal-to-noise ratio. Then, based on validity, optimized detection...

The fighter's demand oxygen system has the problem of high respiratory resistance when supplying according to pilot's rhythm, which will significantly affect comfort and combat mentality. Based on space limitations in cockpit, a state identification is designed built, airflow sensor selected collect data under different states. relationship between states thus established helps clarify logic identification. built been experimentally verified have precision fast response speed, can greatly...

Abstract Background To estimate the global disease burden of uncorrected refractive error (URE) among adolescents and assess contributions various risk factors to disability-adjusted life-years (DALYs) due URE. Methods Global, regional country-level DALY numbers rates URE were acquired from Global Burden Disease Study 2019 database. Human Development Index (HDI), Socio-Demographic (SDI) other data obtained open databases as potential indicators. Regression analysis was used evaluate...

To evaluate the disease burden of glaucoma in terms disability-adjusted life years (DALY) and assess contribution risk factors to DALY due glaucoma.Global, regional, country number, rate, age-standardized rates were obtained from Global Burden Disease Study 2017 database. The Human Development Index (HDI), Inequality-Adjusted HDI, Socio-Demographic (SDI), other country-level data derived international open databases. Regression analysis was used correlations between rate variables.The global...

Uveal melanoma (UVM) is the most common primary ocular malignancy in adults and involves several types of regulated cell death. Cuproptosis a novel method regulating death by binding lipoylated TCA cycle proteins. There still no research on relationship between cuproptosis-related genes (CRGs) UVM. Here, we aimed to develop prognostic CRG signature for After was constructed, determined immune infiltration, bioinformatics analysis experimental validation. Finally, three-gene (CRTG) which...

The role of the IκB/NF-κB signaling pathway in uveoscleral outflow was investigated with IκBα gene silencing mediated by 3-(dimethylamino)-1-propylamine-conjugated glycogen (DMAPA-Glyp) derivative. IκBα-siRNA-loaded DMAPA-Glyp complex transfected into ciliary muscles rats intracameral injection (labeled as DMAPA-Glyp+siRNA group). Lipofectamine™ 2000 (Lipo)/siRNA and naked siRNA were set controls. mRNA protein expression IκBα, NF-κBp65, MMP-2 analyzed real-time PCR, western blotting, situ...

Abstract With the development of aircraft towards high altitude, speed, and long endurance, influence aerodynamic radiant heat on flow transfer in cabin has increased. To explore conditions under ventilation, convection, radiation coupling, a scaled model test was conducted for verification simulation. According to scaling principle, small ventilation box with scale 1: 5 designed simulate boundary grid computing methods by building heating, irradiation systems. The CFD results were compared...

Abstract Background To estimate the global disease burden of uncorrected refractive error (URE) among adolescents and assess contributions various risk factors to disability-adjusted life-years (DALYs) due URE. Methods Global, regional country-level DALY numbers rates URE were acquired from Global Burden Disease Study 2019 database. Human Development Index (HDI), Socio-Demographic (SDI) other data obtained open databases as potential indicators. Regression analysis was used evaluate...

To study the potential incidence of retinopathy in children with febrile seizures.Thirty-four seizures, aged 3 months to 9 years and admitted from January 2000 June 2008, were retrospectively analyzed. All cases received fundus examination within 24 hours after admission was calculated.None subjects found have retinal hemorrhages. Therefore, using Hanley's Rule Three, upper limit 95% confidence interval hemorrhages following seizures is less than 10%.The lower 10%. If are other causes need...

Objective To investigate the inhibitive effects of 5-fluorouracil-loaded polylactic acid nanoparticles (5-FU-PLA-NPs)on human Tenon's capsule fibroblasts in vitro. Methods This paper was experimental study. MTT assay performed to estimate 0.1 mg/L, 1.0 10.0 100.0 1000.0 mg/L unloaded nanoparticles(PLA-NPs) on proliferation 48 h, 72 h. 10. 0 original 5-FU and 5-FU-PLA-NPs fibroblasts' 7 consecutive days respectively. The inhibitory rate two drugs against calculated. Cells were exposed 100...

Objective To evaluate the incidence of dry eye in systemic lupus erythematomous (SLE) patients with or without sjogren syndrome (SS), and to investigate correlation between SLE activ-ity. Methods The records 138 department rheumatology Jan 1st,2006 Dec 30 th ,2008 were reviewed. severity was assessed by Schirmer test(SCH), tear film break up time (BUT), fluorescein staining (FL). activity evaluated titre anti-dsDNA, C3, CA. relationship all indexes analyzed. Results About ten percent met...

Objective To evaluate the correlation between tear dynamics and some immunological factors in rheumatoid arthritis(RA) patients.Methods In 10 RA patients,the were assessed by Schirmer Ⅰ test break-up time(BUT).Edimentation rate(ESR),immunoglobulin M(IgM),rheumatoid factors(RF) Anti-citrullinated protein antibody( Anti-ccp antibody)were collected.The first two correlated with activity last diagnoses of RA.Pearson was used to analyze indexes right eye four respectively.Results The mean was(8.8...

Objective To evaluate the incidence of dry eye in rheumatoid arthritis(RA)patients with or without Sjogren syndrome(SS),and to investigate correlation between and RA activity.Methods The records 158 patients department rheumatology Jan 1st.2003 Dec 30 th, 2006 were reviewed.The severity was assessed by Schirmer test (SCH), tear film break up time (BUT), filuorescein staining (FL).The activity evaluated erythroeyte sedimentation rate (ESR), c-reactive protein(CRP), factor(RF).The relationship...