A5028239812- Cancer Immunotherapy and Biomarkers
- Immune Cell Function and Interaction
- Mentoring and Academic Development
- CAR-T cell therapy research
- Doctoral Education Challenges and Solutions
- Acute Myeloid Leukemia Research
- Diversity and Career in Medicine
- Blood disorders and treatments
- Healthcare professionals’ stress and burnout
- Health and Medical Research Impacts
- Chemokine receptors and signaling
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
University of Washington
2021
Hampton University
2017-2018
Emory University
2018
Key Points Number of prior chemotherapy cycles in cancer patients correlates with T-cell senescent phenotype and loss CD27 CD28 expression. Addition PI3Kδ inhibitors VIP antagonists increased ex vivo expansion, persistence, anticancer cytotoxicity T cells.
Abstract RUNX1 familial platelet disorder (RUNX1-FPD) is an autosomal dominant caused by a monoallelic mutation of RUNX1, initially resulting in approximately half-normal activity. Clinical features include thrombocytopenia, functional defects, and predisposition to leukemia. rapidly degraded through the ubiquitin-proteasome pathway. Moreover, it may autoregulate its expression. A predicted kinetic property autoregulatory circuits that transient perturbations steady-state levels result...
Graduate programs in the biomedical sciences dedicate considerable resources to recruiting students from underrepresented racial and ethnic groups. However, these minoritized groups have decreased access ‘hidden curriculum’ that must be navigated order successful graduate school. Here, we describe a student-led initiative at Johns Hopkins University, Hidden Curriculum Symposium, is organized help prepare new for Preliminary evidence surveys suggests does increase preparedness of students,...
Abstract Problem All trainees, especially those from historically minoritized backgrounds, experience stresses that may reduce their continuation in science, technology, engineering, math, and medicine (STEMM) careers. The Johns Hopkins University School of Medicine is one ∼45 institutions with a National Institutes Health funded Postbaccalaureate Research Education Program (PREP) provides mentoring year fulltime research to prepare students excluded groups for graduate school. Having...