A5085450811- Mass Spectrometry Techniques and Applications
- Analytical Chemistry and Chromatography
- Analytical chemistry methods development
- Electrohydrodynamics and Fluid Dynamics
- Microfluidic and Capillary Electrophoresis Applications
- Ion-surface interactions and analysis
- Gold and Silver Nanoparticles Synthesis and Applications
- Advanced Chemical Physics Studies
- Advanced Sensor and Energy Harvesting Materials
- Catalytic Processes in Materials Science
- Advanced Chemical Sensor Technologies
- Chemical Synthesis and Analysis
- Nanomaterials for catalytic reactions
- Conducting polymers and applications
- Advanced Materials Characterization Techniques
- Atmospheric chemistry and aerosols
- Laser-induced spectroscopy and plasma
- Fullerene Chemistry and Applications
- Gas Sensing Nanomaterials and Sensors
- Protein Interaction Studies and Fluorescence Analysis
- Physical Unclonable Functions (PUFs) and Hardware Security
- Pharmacological Effects and Assays
- Radiation Detection and Scintillator Technologies
- Pickering emulsions and particle stabilization
- Green IT and Sustainability
University of New Hampshire at Manchester
2021-2025
University of New Hampshire
2019-2024
Changzhou University
2024
Purdue University West Lafayette
2011-2020
Georgia Institute of Technology
2017-2019
Foundation for Applied Molecular Evolution
2019
Indian Institute of Technology Madras
2014
Abstract Noble metals can be ionized by electrochemical corrosion and transported electrospray ionization. Mass spectrometry (MS) showed solvated metal ions as the main ionic constituent of sprayed droplets. Collection plume on a surface yielded noble nanoparticles (NPs) under ambient conditions. The NPs were characterized several techniques. Under typical conditions, capped‐nanoparticle sizes averaged 2.2 nm for gold 6.5 silver. high catalytic activity in reduction p ‐nitrophenol NaBH 4 ....
The rapid development of the Internet Things depends on wireless devices and their network. Traditional sensing transmission technology still requires multiple modules for sensing, signal modulation, transmission, power, making whole system bulky, rigid, costly. Here, we proposed a paradigm shift solution based breakdown discharge–induced displacement current. Through that, can combine abovementioned functional in single unit self-powered e-sticker (SWISE), which features small size (down to...
Non-polar solvents like hexane allow ionization of insoluble drugs, peptides, nucleotides and phospholipids as solids from paper. Ambient is achieved simply by application a high voltage to the wet Transport mechanisms are discussed, including possibility field desorption dendritic structures formed on
Rapid qualitative and quantitative analysis of 4-methylimidazole (4-MEI) in caramel beverage samples is demonstrated using the paper spray form ambient ionization mass spectrometry. The minimum level pure 4-MEI detectable multiple reaction monitoring (MRM) a triple quadrupole instrument was 3 pg μL−1 neat solvent 5 matrix containing caramel. This method used to analyze 11 for 4-MEI. After implementing effective quality control protocols, average relative standard deviations MS were less than...
Electrolytic spray deposition was used to pattern surfaces with 2D metallic nanostructures. Spots that contain silver nanoparticles (AgNP) were created by landing solvated ions at desired locations using electrically floated masks focus the metal an area as little 20 μm in diameter. The AgNPs formed are unprotected and their aggregates can be for surface-enhanced Raman spectroscopy (SERS). morphology SERS activity of NP structures controlled surface coverage landed ions. could substrates...
Desorption atmospheric pressure chemical ionization (DAPCI) is implemented on a portable mass spectrometer and applied to the direct detection of polycyclic aromatic hydrocarbons (PAHs) alkyl substituted benzenes. The presence these compounds in environment poses significant threat health both humans wildlife because their carcinogenic, toxic, mutagenic properties. As such, instant outside laboratory particular importance allow in-situ measurement at source. Using rapid, high throughput,...
Abstract Relay electrospray ionization (rESI) from a capillary containing sample solution (or an array of such capillaries) is triggered by charge deposition onto the capillary. Suitable sources primary ions, besides electrosprays, are plasma ion and piezoelectric discharge sources. With no requirement for physical contact, high‐throughput screening enabled rapidly addressing individual secondary (sample) capillaries. Sub‐pL volumes can be loaded sprayed. Polar analytes, including...
Endohedral metallofullerenes are chemically more inert compared to empty fullerenes, primarily due their intramolecular electron transfer. In this work, we report an inverse demand Diels‐Alder (IEDDA) reaction on M3N@C80 (M= Lu, Sc), where they show significantly higher reactivity than fullerenes. The molecular structures of the [4+2] cycloadducts were unambiguously characterized. Moreover, can fully revert pristine via retro‐cycloaddition upon thermal treatment. With unusual and...
Endohedral metallofullerenes are chemically more inert compared to empty fullerenes, primarily due their intramolecular electron transfer. In this work, we report an inverse demand Diels-Alder (IEDDA) reaction on M3N@C80 (M= Lu, Sc), where they show significantly higher reactivity than fullerenes. The molecular structures of the [4+2] cycloadducts were unambiguously characterized. Moreover, can fully revert pristine via retro-cycloaddition upon thermal treatment. With unusual and...
A novel, lightweight (0.6 kg), solvent- and gas-cylinder-free, hand-held ion source based on desorption atmospheric pressure chemical ionization has been developed deployed for the analysis of nitroaromatic explosives surfaces in open air, offering portability in-field analysis. small, inexpensive, rechargeable lithium polymer battery was used to power custom-designed circuitry within device, which generates up ±5 kV dc voltage ignite a corona discharge plasma air 12 h continuous operation,...
Atmospheric pressure drift tube ion mobility spectrometry (AP-DTIMS) was coupled with Fourier transform Orbitrap mass spectrometry. The performance capabilities of this versatile new arrangement were demonstrated for different DTIMS gating operation modes and spectrometer parameters regard to sensitivity resolving power. Showcasing the optimized AP-DTIMS-Orbitrap MS system, isobaric peptide sugar isomers successfully resolved identities separated species validated by high-energy collision...
Paper spray (PS) ambient ionization is implemented using a portable mass spectrometer and applied to the detection of alkyl quaternary ammonium salts in complex oil matrix. These are commonly used as active components formulation corrosion inhibitors. They were identified confirmed by their fragmentation patterns recorded tandem spectrometry (MS/MS). The cations benzyl-substituted showed characteristic neutral losses CnH2n (n carbon number longest chain) C7H8, respectively. Individual...
An ambient solution-state method for making uniform nanobrushes composed of oriented 1D silver nanowires (NWs) with aspect ratios 10(2) -10(4) is reported. These structures are grown over cm(2) areas on conducting surfaces. Assemblies NWs form nanobrush structures, which can capture micrometer-sized objects, such as bacteria and particulate matter. Variation in composition produces unique catalytic properties.
The triboelectric nanogenerator (TENG) has been invented as a technology for harvesting mechanical energy, well allocating quantized charge scientific instruments. generation of the TENG is mainly related to effect or contact electrification (CE) usually described by potential-well-electron-cloud model, while transfer difference in occupied energy levels electrons. However, our experiment, we observed an abnormal phenomena between ternary materials, which cannot be explained level only. To...
Femto flow electrospray ionization (ESI) with rates ranging from 240 fL min-1 to the low pico level (<10 pL min-1) was conducted and measured using a submicron emitter tip relay ESI configuration. Signature analyte ion current intensities profiles were observed. The obtained rate enabled size calculation for initial charged nanodroplets.
Many technologies currently exist that are capable of analyzing the surface solid samples under ambient or vacuum conditions, but they typically limited to smooth, planar surfaces. Those few can be applied nonplanar surfaces, however, require manual sampling and a high degree human intervention. Herein, we describe new platform, Robotic Surface Analysis Mass Spectrometry (RoSA-MS), for direct three-dimensional (3D) objects. In RoSA-MS, probe is attached robotic arm has 360° rotation through...
An epidemic of low quality medicines continues to endanger patients worldwide. Detection such "medicines" requires cost, ambient ionization sources coupled fieldable mass spectrometers for optimum sensitivity and specificity. With the use triboelectric nanogenerators (TENGs), charge required produce gas-phase ions analysis can be obtained without need high voltage electrical circuitry, simplifying lowering cost next-generation spectrometry instruments.
Rh-catalyzed decomposition of ethanol into CO2 and CH4 via C-C bond splitting is reported in room-temperature liquid phase under atmospheric pressure. Mechanistic investigations show that on the noble metal surface rapid, forms through oxidation α-CH xO β-CH x fragments after splitting, while hydrogenation utilizing H atoms from -OH, x, xOH fragments.
The reactivity of aryl cations toward molecular nitrogen is studied systematically in an ion trap mass spectrometer at 10(2) Pascal nitrogen, the pressure Titan main haze layer. Nucleophilic addition dinitrogen occurs and nature group has a significant influence on reactivity, through inductive effects by changing ground state spin multiplicity. products activation, aryldiazonium ions, react with typical nitriles, aromatic amines, alkynes (compounds that are relevant as possible atmosphere...
Synthese mit Ionen unter Umgebungsbedingungen: Peptide werden fast augenblicklich und quantitativ vernetzt, wenn man sie als Lösung in Mikrotröpfchen auf eine Oberfläche dem Vernetzungsreagens sprüht (siehe Bild). Die Reaktion kann einer offenen Laborumgebung durchgeführt werden, auch die umgekehrte Vorgehensweise ist möglich.
Abstract Electrolytic spray deposition was used to pattern surfaces with 2D metallic nanostructures. Spots that contain silver nanoparticles (AgNP) were created by landing solvated ions at desired locations using electrically floated masks focus the metal an area as little 20 μm in diameter. The AgNPs formed are unprotected and their aggregates can be for surface‐enhanced Raman spectroscopy (SERS). morphology SERS activity of NP structures controlled surface coverage landed ions. could...
Abstract Noble metals can be ionized by electrochemical corrosion and transported electrospray ionization. Mass spectrometry (MS) showed solvated metal ions as the main ionic constituent of sprayed droplets. Collection plume on a surface yielded noble nanoparticles (NPs) under ambient conditions. The NPs were characterized several techniques. Under typical conditions, capped‐nanoparticle sizes averaged 2.2 nm for gold 6.5 silver. high catalytic activity in reduction p ‐nitrophenol NaBH 4 ....