Tiong Kai Tan

ORCID: 0000-0003-0297-1727
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About
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Research Areas
  • Insect symbiosis and bacterial influences
  • Vector-borne infectious diseases
  • Mosquito-borne diseases and control
  • Viral Infections and Vectors
  • Parasitic Diseases Research and Treatment
  • Freshwater macroinvertebrate diversity and ecology
  • Malaria Research and Control
  • Parasites and Host Interactions
  • Parasite Biology and Host Interactions
  • Parasitic Infections and Diagnostics
  • Helminth infection and control
  • Insect behavior and control techniques
  • Insect Pest Control Strategies
  • Bartonella species infections research
  • Amoebic Infections and Treatments
  • Environmental DNA in Biodiversity Studies
  • Genetic diversity and population structure
  • Viral gastroenteritis research and epidemiology
  • Child Nutrition and Water Access
  • Insect Resistance and Genetics
  • Vector-Borne Animal Diseases
  • Insect and Pesticide Research
  • Reproductive tract infections research
  • Coccidia and coccidiosis research
  • Mollusks and Parasites Studies

University of Malaya
2015-2024

Biodiversity Research Center, Academia Sinica
2017-2024

Ministry of Agriculture and Agro Based Industry
2022

The morphotaxonomy of Rhipicephalus microplus complex has been challenged in the last few years and prompted many biologists to adopt a DNA-based method for distinguishing members this group. In present study, we used mitochondrial DNA analysis characterise genetic assemblages, population structure dispersal pattern R. from Southeast Asia, region where species originated. A phylogeographic inferred 16S rRNA cytochrome oxidase subunit I (COI) genes was performed with five populations...

10.1186/s13071-015-0956-5 article EN cc-by Parasites & Vectors 2015-06-23

A cross-sectional study was conducted to provide comprehensive data on the patterns and associated risk factors of soil-transmitted helminth (STH) infections among five Orang Asli subgroups in Peninsular Malaysia. The overall prevalence STH 59.9% (95% confidence interval [CI] = 56.1–63.7%). Trichuris trichiura (54.3%; 95% CI 50.4–58.2%) predominant species followed by Ascaris lumbricoides (26.7%; 23.3–30.1%) hookworm (9.1%; 6.9–11.3%). This showed diversity for subgroup with poverty personal...

10.4269/ajtmh.13-0677 article EN American Journal of Tropical Medicine and Hygiene 2015-06-10

Background There has been no comprehensive study on biochemical characterization of insecticide resistance mechanisms in field populations Malaysian Culex quinquefasciatus. To fill this void the literature, a nationwide investigation was performed to quantify enzyme activities, thereby attempting characterize potential Cx. quinquefasciatus residential areas Malaysia. Methodology/Principal Findings from 14 across 13 states and one federal territory were subjected esterases, mixed function...

10.1371/journal.pone.0079928 article EN cc-by PLoS ONE 2013-11-21

The population genetic structure of Simulium tani was inferred from mitochondria-encoded sequences cytochrome c oxidase subunits I (COI) and II (COII) along an elevational gradient in Cameron Highlands, Malaysia. A statistical parsimony network 71 individuals revealed haplotypes the COI gene 43 COII gene; concatenated genes haplotypes. High levels diversity but low differentiation were observed among populations S. at five elevations. degree diversity, however, not accordance with...

10.1371/journal.pone.0100512 article EN cc-by PLoS ONE 2014-06-18

Canine babesiosis is an emerging tick-borne disease with a worldwide distribution, including Malaysia. While the prevalence of Babesia has been documented from dogs in Malaysia, occurrence relatively little studied their tick vectors. Accordingly, total 240 and 140 Rhipicephalus sanguineus sensu lato (s.l.) (Acari: Ixodidae) ticks Malaysia were molecularly screened for presence protozoa present study. gibsoni was only detected (1.4%), whereas vogeli both (1.4%) (2.1%). This study highlights...

10.1093/jme/tjy072 article EN Journal of Medical Entomology 2018-05-12

Given that there is limited available information on the insensitive acetylcholinesterase in insect species Malaysia, present study aims to detect presence of G119S mutation gene Culex quinquefasciatus from 14 residential areas across 13 states and a federal territory Malaysia.The ace-1 sequence PCR-RFLP test revealed glycine-serine wild populations Cx. quinquefasciatus. Both direct sequencing methods demonstrated similar results heterozygous genotype at very low frequency (18 out 140...

10.1002/ps.3512 article EN Pest Management Science 2013-02-13

Soil-transmitted helminth (STH) infections have been documented among these minority groups since 1938. However the prevalence of STH is still high communities. Most studies tend to consider Orang Asli (indigenous) as a homogenous group. In contrary, different subtribes their own cultural practices. To understand this variation better, we studied and associated factors other gut parasitic two common (i.e. Temuan Temiar). Results showed that overall was higher in subtribe (53.2% 171) compared...

10.1371/journal.pone.0107980 article EN cc-by PLoS ONE 2014-09-23

Hepatozoon canis has been widely reported in dogs. Its prevalence ticks, however, not well-established. Here we determine the occurrence of DNA brown dog tick Rhipicephalus sanguineus (Latreille) (Acari: Ixodidae) sensu lato (s.l.) and domestic dogs from Peninsular Malaysia using a polymerase chain reaction (PCR) assay based on amplification 18S ribosomal RNA coding sequence. Our results revealed relatively low H. both R. s.l. (0.7%) (3.33%). This study represents first report Malaysia,...

10.1093/jme/tjy081 article EN Journal of Medical Entomology 2018-05-17

Abstract The present study explored the intraspecific genetic diversity, dispersal patterns and phylogeographic relationships of Culex quinquefasciatus Say (Diptera: Culicidae) in Malaysia using reference data available GenBank order to reveal this species' phylogenetic relationships. A statistical parsimony network 70 taxa aligned as 624 characters cytochrome c oxidase subunit I ( COI ) gene 685 II COII revealed three haplotypes A1–A3 four B1–B4 ), respectively. concatenated sequences both...

10.1111/mve.12022 article EN Medical and Veterinary Entomology 2013-07-15

The emergence of pyrethroid resistance in Aedes aegypti (L.) has limited the success vector control. Early detection could assist authorities deciding well-suited control strategies to minimize operational failures Ae. Herein, biochemical analysis was performed investigate mechanisms involved nine populations Indonesian aegypti. Enzymes adult such as esterases (ESTs), glutathione-S-transferases (GSTs), and mixed-function oxidases (MFOs) were characterized. Elevated MFO activity correlated...

10.1093/jme/tjz007 article EN Journal of Medical Entomology 2019-02-01

Uncovering the hidden diversity and evolutionary history of arthropods medico-veterinary importance could have significant implications for vector-borne disease control epidemiological intervention. The buffalo fly Haematobia exigua is an obligate bloodsucking ectoparasite livestock. As initial step towards understanding its population structures biogeographic patterns, we characterized partial cytochrome c oxidase subunit I (COI) b (Cytb) sequences H. from three distinct geographic regions...

10.1038/s41598-017-05921-w article EN cc-by Scientific Reports 2017-07-13

Abstract Previous studies suggested the presence of species complex in so-called Simulium asakoae Takaoka & Davies (Diptera: Simuliidae) Thailand due to its high morphological variability and genetic divergence. To investigate whether true S. is present Thailand, we performed a detailed identification compared DNA barcodes with morphospecies from Myanmar typical Malaysia. Phylogenetic analysis revealed Thai materials analyzed this study were indeed genetically similar those Malaysia,...

10.1093/jme/tjaa081 article EN Journal of Medical Entomology 2020-04-25
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