Arun Gupta
A5101808246- Inflammatory Bowel Disease
- Diverticular Disease and Complications
- Appendicitis Diagnosis and Management
- Microscopic Colitis
- Anorectal Disease Treatments and Outcomes
- Colorectal Cancer Surgical Treatments
- Colorectal Cancer Screening and Detection
- Gastrointestinal disorders and treatments
- Colorectal and Anal Carcinomas
- Esophageal and GI Pathology
- Soft tissue tumor case studies
- Intestinal Malrotation and Obstruction Disorders
- Radiomics and Machine Learning in Medical Imaging
- AI in cancer detection
- Hernia repair and management
- Renal and related cancers
- Gastrointestinal Bleeding Diagnosis and Treatment
- Sarcoma Diagnosis and Treatment
- Diagnosis and treatment of tuberculosis
- Gastric Cancer Management and Outcomes
- Urologic and reproductive health conditions
- Mycobacterium research and diagnosis
- Biliary and Gastrointestinal Fistulas
- Breast Lesions and Carcinomas
- Breast Cancer Treatment Studies
St Mark's Hospital
2015-2025
Government Ayurvedic College and Hospital
2024
Imperial College London
2011-2024
London North West Healthcare NHS Trust
2018-2023
University College London
2022
Institute of Medical Sciences
2021
Sri Ramakrishna Institute of Paramedical Sciences
2021
National Health Service
2018-2019
St. Mark's Hospital
2018
St Mary's Hospital
2017
Consensus abstract Background The management of primary rectal cancer beyond total mesorectal excision planes (PRC-bTME) and recurrent (RRC) is challenging. There global variation in standards no guidelines exist. To achieve cure most patients require extended, multivisceral, exenterative surgery, conventional planes. aim the Beyond TME Group was to consensus on definitions principles management, identify areas research priority. Methods Delphi methodology used consensus. consisted invited...
Magnetic resonance enterography (MRE) and ultrasound are used to image Crohn's disease, but their comparative accuracy for assessing disease extent activity is not known with certainty. Therefore, we did a multicentre trial address this issue.
Consensus abstract Background The management of primary rectal cancer beyond total mesorectal excision planes (PRC-bTME) and recurrent (RRC) is challenging. There global variation in standards no guidelines exist. To achieve cure most patients require extended, multivisceral, exenterative surgery, conventional planes. aim the Beyond TME Group was to consensus on definitions principles management, identify areas research priority. Methods Delphi methodology used consensus. consisted invited...
To compare patient acceptability and burden of magnetic resonance enterography (MRE) ultrasound (US) to each other, other enteric investigations, particularly colonoscopy.159 patients (mean age 38, 94 female) with newly diagnosed or relapsing Crohn's disease, prospectively recruited a multicentre diagnostic accuracy study comparing MRE US completed an experience questionnaire on the small bowel investigations between December 2013 September 2016. Acceptability, recovery time, scan...
To prospectively compare the diagnostic performance and time efficiency of both second concurrent computer-aided detection (CAD) reading paradigms for retrospectively obtained computed tomographic (CT) colonography data sets by using consensus (three radiologists) colonoscopic findings as a reference standard.Ethical permission, HIPAA compliance (for U.S. institutions), patient consent were from all institutions use CT in this study. Ten radiologists each read 25 (12 men, 13 women; mean age,...
Peutz-Jeghers syndrome (PJS) in children may present with anaemia, intussusception, or obstruction from an early age and surgery is common. Prophylactic polypectomy reduce subsequent complications. Traditional barium enterography (BE) has poor sensitivity requires significant radiation. We compared the performance of capsule endoscopy (CE) BE PJS.Children PJS (ages 6.0-16.5 years) were prospectively recruited underwent followed by CE, each reported expert reviewers blinded to alternate...
Abstract Background Small bowel Crohn’s disease (SBCD) is increasingly treated with biological therapies. Predicting response or remission (RoR) for individual patients difficult and complicates treatment strategy. We aimed to determine if motility magnetic resonance imaging (mMRI) superior CRP fecal calprotectin (FC) the prediction of RoR at 1 year in commencing biologics SBCD. Methods Prospective, multicenter (n = 13) cohort study active non-stricturing SBCD requiring anti-TNFα...
Abstract Objectives Altered body fat and muscle mass in Crohn’s disease (CD) have been linked to adverse course outcomes. Prediction of treatment response or remission (RoR) small bowel CD (SBCD) biologic therapy remains challenging. We aimed establish the prognostic value composition parameters measured using MR enterography (MRE) for RoR at 1 year patients with SBCD commencing therapy. Methods Participants were identified from those recruited a prospective, multicentre study investigating...
Anti-tumour necrosis factor (TNF) therapy effectively treats Crohn's perineal fistulas (CPF); the effect on health-related quality of life (HRQoL) remains unknown.To evaluate anti-TNF HRQoL patients with CPF in daily clinical practice.Prospective evaluation and magnetic resonance imaging (MRI) responses, disease activity (Perianal Disease Activity Index - PDAI), assessment [Inflammatory Bowel Questionnaire (IBDQ)] receiving for treated up to 12 months.In all, 26 were (mean age 39 years; 19...
Crohn's disease (CD) is a lifelong, relapsing and remitting inflammatory condition of the intestine. Medical imaging crucial for diagnosis, phenotyping, activity assessment detecting complications. Diverse small bowel tests are available but standard algorithm deployment lacking. Many hospitals employ that impart ionising radiation, particular concern to this young patient population. Magnetic resonance enterography (MRE) ultrasound (USS) attractive options, as they do not use radiation....
ObjectivesTo evaluate the additional diagnostic benefit of diffusion weighted imaging (DWI) and contrast enhanced (CE) images during MR enterography (MRE) Crohn's disease.MethodsDatasets from 73 patients (mean age 32; 40 male) (28 new-diagnosis, 45 relapsed) were read independently by two radiologists selected a pool 13. Radiologists interpreted datasets using three sequential sequence blocks: (1) T2 steady state free precession gradient echo (SSFP) alone (T2^); (2) SSFP with DWI (T2 + DWI^)...
To evaluate interobserver variability for diagnosis of disease presence and extent small bowel colonic Crohn's using MR enterography (MRE).Data from the first 73 consecutive patients (mean age 32, 33F, 28 new diagnosis, 45 suspected relapse) recruited to a multicentre, prospective diagnostic accuracy trial evaluating MRE were each read independently by three (from pool 20) radiologists. Radiologists documented segmental location recorded morphological mural/extramural parameters involved...
Objective: Desmoid tumour is a common extraintestinal manifestation of patients with familial adenomatous polyposis (FAP) who have undergone prophylactic colectomy. We aimed to determine whether MRI provides equivalent or better assessment desmoid tumours than CT, the current first-line investigation. Methods: Following ethics approval and informed consent, FAP known underwent contrast-enhanced 64-slice multidetector CT (MDCT) 1.5 T (incorporating T1 weighted, T2 short tau inversion–recovery...
Background Most radiologists reporting CT colonography (CTC) do not undergo compulsory performance accreditation, potentially lowering diagnostic sensitivity. Purpose To determine whether 1-day individualized training in CTC improves sensitivity of experienced for 6-mm or larger lesions, the durability any improvement, and associated factors. Materials Methods This prospective, multicenter cluster-randomized controlled trial was performed National Health Service hospitals England Wales...
The simplified magnetic resonance enterography [MRE] index of activity [sMARIA], London, and 'extended' scoring systems are widely used in Crohn's disease [CD] to assess activity, although validation studies have usually been single-centre, retrospective, and/or few readers. Here, we evaluated these MRE indices within a prospective, multicentre, multireader, diagnostic accuracy trial.A subset participants [newly diagnosed or suspected relapse] recruited the METRIC trial with available...
Sahnan, Kapil BSc (Hons), MBBS, MRCS; Adegbola, Samuel O. Tozer, Phillip J. MD, MCEM, FRCS; Gupta, Arun MBChB, MRCP, FRCR; Baldwin-Cleland, Rachel MSc; Yassin, Nuha MRCS, PhD; Warusavitarne, Janindra BMed, FRACS, Faiz, Omar D. FRCS, MS; Hart, Ailsa L. BA BMBCh, FRCP, Phillips, Robin K. S. Lung, F. C. FRCR Author Information
Magnetic resonance enterography and enteric ultrasonography are used to image Crohn's disease patients. Their diagnostic accuracy for presence, extent activity of was compared. To compare accuracy, observer variability, acceptability, impact cost-effectiveness magnetic in newly diagnosed or relapsing disease. Prospective multicentre cohort study. Eight NHS hospitals. Consecutive participants aged ≥ 16 years, with established suspected relapse. ultrasonography. The primary outcome...
Abstract Objectives The simple ultrasound activity score for Crohn’s disease (SUS-CD) and bowel (BUSS) are promising intestinal (IUS) indices of CD, but studied mainly in small settings with few sonographers. We compared SUS-CD BUSS against histological magnetic resonance enterography (MRE) reference standards a post hoc analysis prospective multicentre, multireader trial. Methods Participants recruited to the METRIC trial (ISRCTN03982913) were studied, including those available terminal...
To survey the perceived indications for magnetic resonance imaging of small bowel (MRE) by experts, when MR enteroclysis (MREc) or enterography (MREg) may be chosen, and to determine how approach MRE is modified general anaesthesia (GA) required.Selected opinion leaders in completed a questionnaire that included clinical (MREg MREc), specifics regarding administration enteral contrast, technique altered accommodate GA.Fourteen responded. Only diagnosis follow-up Crohn's disease were...