A5031613679- Inflammatory Bowel Disease
- Helicobacter pylori-related gastroenterology studies
- Microscopic Colitis
- Gastric Cancer Management and Outcomes
- Eosinophilic Esophagitis
- Gastrointestinal disorders and treatments
- Colorectal Cancer Screening and Detection
- Biosimilars and Bioanalytical Methods
- Gastroesophageal reflux and treatments
- Veterinary medicine and infectious diseases
- Gastrointestinal Bleeding Diagnosis and Treatment
- Gastrointestinal motility and disorders
- Diagnosis and treatment of tuberculosis
- Gastrointestinal Tumor Research and Treatment
- Diverticular Disease and Complications
- Pharmaceutical studies and practices
- Autoimmune and Inflammatory Disorders
- Colorectal Cancer Treatments and Studies
- Galectins and Cancer Biology
- Chronic Lymphocytic Leukemia Research
- Monoclonal and Polyclonal Antibodies Research
- Child Nutrition and Feeding Issues
- Pancreatic and Hepatic Oncology Research
- Cutaneous Melanoma Detection and Management
- Pregnancy and Medication Impact
Tallaght University Hospital
2013-2024
Trinity College Dublin
2012-2024
University Hospital Galway
2018-2022
University College London
2022
Leeds Teaching Hospitals NHS Trust
2015-2021
Cancer Trials Ireland
2018-2020
St James's University Hospital
2014-2018
Trinity College
2018
University Gastroenterology
2009-2015
Beth Israel Deaconess Medical Center
2014-2015
Atrophic gastritis, intestinal metaplasia, and epithelial dysplasia of the stomach are common associated with an increased risk for gastric cancer. In absence guidelines, there is wide disparity in management patients these premalignant conditions. The European Society Gastrointestinal Endoscopy (ESGE), Helicobacter Study Group (EHSG), Pathology (ESP) Sociedade Portuguesa de Endoscopia Digestiva (SPED) have therefore combined efforts to develop evidence-based guidelines on precancerous...
Magnetic resonance enterography (MRE) and ultrasound are used to image Crohn's disease, but their comparative accuracy for assessing disease extent activity is not known with certainty. Therefore, we did a multicentre trial address this issue.
Objectives: Recently, the infliximab biosimilar (CT-P13) received market authorisation for inflammatory bowel disease (IBD), allowing cost benefits when switching to CT-P13. We aim assess efficacy and safety of from originator CT-P13 new existing patients.Material methods: Treatment response, remission, primary secondary loss response rates, adverse events in patients who initiated 12 months pre-switch (n = 53) were compared with post-switch 69). Sustained responses switched 191) those...
Background: Ipilimumab is an anticytotoxic T-lymphocyte antigen-4 (CTLA-4) monoclonal antibody used for the treatment of malignant melanoma. It can cause immune-mediated inflammatory adverse events, including diarrhoea and even intestinal perforation or death in clinical trials but there a dearth data on postmarketing outcomes. Methods: A total 546 patients attending metastatic melanoma between 1 January 2009 31 August 2015 were identified by interrogation oncology database. 83 these...
Irish eradication rates for Helicobacter pylori are decreasing and there is an increase in the prevalence of antibiotic-resistant bacteria. These trends call into question current management strategies.To establish Working Group (IHPWG) to assess, revise tailor available recommendations.Experts areas gastroenterology microbiology were invited join IHPWG. Questions relevance diagnosis, first-line rescue therapy developed using PICO system. A literature search was performed. The 'Grading...
BACKGROUND Surveillance colonoscopies are predominantly normal, identifying patients for potential polypectomy is advantageous. AIM To assess colon capsule endoscopy (CCE) and/or faecal immunochemical test (FIT) as filters in surveillance. METHODS Patients aged ≥ 18 due polyp surveillance were invited CCE and FIT. Identifying polyps or colorectal cancer resulted a positive CCE. Significant lesions (≥ 3 6 mm polyps), incomplete studies FITs 225 ng/mL) referred endoscopy. results, FIT accuracy...
Helicobacter pylori eradication rates have fallen considerably in recent years. Antibiotic resistance is thought to be rising.To examine the levels of metronidazole (MTZ) and clarithromycin (CLA) H. pylori, isolates were taken a reference centre Ireland from 2007 2008 compared similar cohort study 1997.Antimicrobial susceptibilities tested by E-test. Frequencies spontaneous measured on an agar plate containing antibiotics at concentrations 2x 4x minimum inhibition concentration values....