A5101626652- Historical Studies in Latin America
- Acute Lymphoblastic Leukemia research
- History and Politics in Latin America
- Childhood Cancer Survivors' Quality of Life
- Latin American history and culture
- Family Dynamics and Relationships
- Insurance, Mortality, Demography, Risk Management
- Hemoglobinopathies and Related Disorders
- Acute Myeloid Leukemia Research
- Demographic Trends and Gender Preferences
- Sports and Physical Education Studies
- Business, Education, Mathematics Research
- Drilling and Well Engineering
- Rock Mechanics and Modeling
- Hydraulic Fracturing and Reservoir Analysis
- Glioma Diagnosis and Treatment
- Global Health Care Issues
- Thermodynamic properties of mixtures
- demographic modeling and climate adaptation
- Lymphoma Diagnosis and Treatment
- Mexican Socioeconomic and Environmental Dynamics
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Migration, Aging, and Tourism Studies
- Phase Equilibria and Thermodynamics
- Sarcoma Diagnosis and Treatment
Universidad Autónoma de Madrid
2001-2024
Universitat de Barcelona
1994-2024
Universidad de Salamanca
2006-2024
Institut d'Investigació Biomédica de Bellvitge
2024
Italian Institute of Technology
2016-2024
Northwestern University
2023
Universidad Autónoma del Estado de Hidalgo
2022
National Institute of Anthropology and History
2022
El Colegio de México
1993-2021
Instituto Politécnico Nacional
2012-2020
Lowest‐low fertility, defined as a period total fertility rate at or below 1.3, has rapidly spread in Europe during the 1990s. This article traces emergence of this new phenomenon to interaction five factors. First, tempo and compositional distortions reduce associated level cohort fertility. Second, socioeconomic changes—including increased returns human capital high economic uncertainty early adulthood—have made late childbearing rational response for individuals couples. Third, social...
Concrete, bone and shale have one thing in common: their load‐bearing mineral phase is a hydrated nanocomposite. Yet the link between material genesis, microstructure, mechanical performance for these materials still an enigma that has deceived many decoding attempts. In this article, we advance statistical indentation analysis techniques make it possible to assess, situ , nanomechanical properties, packing density distributions, morphology of nanocomposites. These are applied identify...
The influence of solute–solvent and solvent–solvent interactions on the preferential solvation solvatochromic indicators in binary solvent mixtures Bipolar hydrogen bond acceptors has been studied. Several equations based exchange models that relate transition energy Dimroth–Reichardt ET(30) indicator with composition are derived compared. tested assume two solvents mixed interact to form a common structure an value not always intermediate between those mixed. can be preferentially solvated...
Leukemic cells in 15 to 25 percent of patients with acute lymphoblastic leukemia (ALL) express myeloid antigens as well lymphoid (the latter reflecting B-cell or T-cell lineage). The relations myeloid-antigen expression other features ALL and prognosis have been controversial.We analyzed clinical laboratory present at diagnosis 236 consecutive cases children. Immunophenotyping, including single- dual-fluorescence analyses, was used classify leukemic B T lymphoblasts also identify...
Magnetic tubular implantable microrobots are batch fabricated by electroforming. These microdevices can be used in targeted drug delivery and minimally invasive surgery for ophthalmologic applications. shapes fitted into a 23-gauge needle enabling sutureless injections. Using 5-degree-of-freedom magnetic manipulation system, the microimplants conveniently maneuvered biological environments. To increase their functionality, tubes coated with biocompatible films successfully filled drugs.
PURPOSE: To determine surgical resectability, event-free survival (EFS), and toxicity in children with hepatocellular carcinoma (HCC) randomized to treatment either cisplatin (CDDP), vincristine, fluorouracil (regimen A) or CDDP continuous-infusion doxorubicin B). PATIENTS AND METHODS: Forty-six patients were enrolled onto Pediatric Intergroup Hepatoma Protocol INT-0098 (Pediatric Oncology Group (POG) 8945/Children’s Cancer (CCG) 8881). After initial surgery biopsy, stage I (n = 8), III 25),...
In this paper we introduce a new set of tempo-adjusted period parity progression measures in order to account for two distinct implications caused by delays childbearing: tempo distortions imply an underestimation the quantum fertility obse
To identify factors which might be associated with intellectual function following treatment for childhood acute lymphoblastic leukemia, 50 long-term survivors were studied using the Wechsler Intelligence Scale Children-Revised. All patients diagnosed between 1972 and 1974 treated on a single clinical trial protocol identical induction maintenance chemotherapy plus central nervous system prophylaxis that included cranial radiation. The mean full scale IQ score group was 95 (SEM 2.0), verbal...
Abstract One hundred eighty‐seven patients diagnosed with acute lymphoblastic leukemia (ALL) between 1972 and 1975 were evaluated for height 6.4–8.8 years (median 7.2 years) from the time of diagnosis their disease. All had been treated on protocols CCG‐101/143 conducted by Childrens Cancer Study Group. After induction remission, received either cranial radiation plus six doses intrathecal methotrexate, craniospinal radiation, or abdominal followed systemic maintenance chemotherapy 3 5...
Abstract An inverse micromechanics approach allows interpretation of nanoindentation results to deliver cohesive‐frictional strength behavior the porous clay binder phase in shale. A recently developed homogenization model, using Linear Comparison Composite approach, considers as a granular material with solid phase. This model is employed Limit Analysis Solver study indentation hardness responses and develop scaling relationships for packing density. Using an on variety shale materials...
Aberrant expression ratio of Cl− transporters, NKCC1 and KCC2, is implicated in several brain conditions. inhibition by the FDA-approved diuretic drug, bumetanide, rescues core symptoms rodent models and/or clinical trials with patients. However, bumetanide has a strong effect due to kidney transporter NKCC2, creating critical drug compliance issues health concerns. Here, we report discovery new chemical class selective inhibitors lead candidate ARN23746. ARN23746 restores physiological...
En los últimos veinticinco años la fecundidad española medida por el ISF ha experimentadouna caída muy importante, alcanzando niveles de entre más bajos del mundo. Esto ocurridosimultáneamente con un retraso en edad al tener hijos. este artículo presentamosresultados investigaciones recientes sobre cómo retrasos hijos hacenque sea pequeño que se observaría si a maternidad fuera estable. Setrata denominado efecto calendario. Mediante aplicación caso español métodosde corrección calendario...
Standard IQ tests were performed in 70 children and adolescents 3.5-10 years (median 5 yrs) after 24 Gy cranial irradiation, with or without concurrent intrathecal methotrexate, for central nervous system prophylaxis of acute lymphoblastic leukemia. Lower scores correlated younger age, female gender, concomitant methotrexate therapy. Multivariate analysis identified age as the most important determinant three factors. The lowest observed girls who less than old at time irradiation received...
Twenty-six cases of childhood rhabdom yosarcoma involving the pelvis were treated at Childrens Hospital Los Angeles between 1950 and 1972.The median survival 1 7 patients up to 1970 was 6 months.Of a group 9 with intensive chemotherapy (ICG) prior surgery and/or xray therapy, 5 are surviving from 12 60 months have relative rate 4.5 times that mixed therapy (MTG) ( p = 0.01).Deaths occurred only in Stage IV disease.The use preoperative or without x-ray followed by local surgical excision when...