- Pancreatic function and diabetes
- Cardiovascular Function and Risk Factors
- Biomedical Research and Pathophysiology
- Cardiac Fibrosis and Remodeling
- Atherosclerosis and Cardiovascular Diseases
- Intracranial Aneurysms: Treatment and Complications
- Adipokines, Inflammation, and Metabolic Diseases
- Physics and Engineering Research Articles
- Cardiovascular Disease and Adiposity
- Intracerebral and Subarachnoid Hemorrhage Research
- Cardiac Imaging and Diagnostics
- Adipose Tissue and Metabolism
- PARP inhibition in cancer therapy
- Viral Infectious Diseases and Gene Expression in Insects
- Sirtuins and Resveratrol in Medicine
- Traumatic Brain Injury and Neurovascular Disturbances
- Cardiovascular Syncope and Autonomic Disorders
- History of Medicine Studies
Universitätsklinikum Würzburg
2016-2024
Comprehensive Cancer Center Mainfranken
2020
Adipocyte cell culture is an important tool for mechanistic studies of energy metabolism. Many factors affect the differentiation adipocytes in culture. Oil red O staining can be used to assess degree differentiation. However, validity this method quantitative analysis has not yet been established. Here we show that a protocol with arbitrarily chosen parameters does measure linear range and suitable (R2 = 0.077, p 0.382), develop validate optimized oil cultured adipocytes. 3T3-L1...
Aim: Nicotinamide N-methyltransferase (NNMT) is a novel regulator of energy homeostasis in adipose tissue. NNMT expression higher obese mice than lean mice, and knockdown prevents diet-induced obesity. Little known about the regulation enzyme activity during development The aim this study was to analyze tissues with incipient established Methods: A fluorescence-based, sensitive, low-volume, high-throughput method developed assay activity. C57BL/6 were fed high-fat diet for 4 weeks (incipient...
Purpose: After acute myocardial infarction (MI), lymphocytes play a pivotal role in the scar formation and remodeling of remote myocardium. Activation takes places mediastinal lymph nodes (MLN). Therefore, imaging MLN as read-out adaptive immune response to MI may identify subjects at increased risk for cardiac functional decline. Methods: The on-going prospective study (NCT05519735) enrolls patients with ST-elevation followed by complete reperfusion multimodal C-X-C motif chemokine receptor...