A5051099314- Lipoproteins and Cardiovascular Health
- Pharmaceutical Practices and Patient Outcomes
- Health Systems, Economic Evaluations, Quality of Life
- Pharmaceutical Economics and Policy
- Blood Pressure and Hypertension Studies
- Medication Adherence and Compliance
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Medical and Biological Sciences
- Innovations in Medical Education
- Diabetes Treatment and Management
- Pharmaceutical studies and practices
- Hormonal Regulation and Hypertension
- Pharmacology and Obesity Treatment
- Antiplatelet Therapy and Cardiovascular Diseases
- Health Sciences Research and Education
- Cancer, Lipids, and Metabolism
- Potassium and Related Disorders
- Sodium Intake and Health
- Diabetes Management and Research
- Gout, Hyperuricemia, Uric Acid
- Healthcare Policy and Management
- Patient Safety and Medication Errors
- Venous Thromboembolism Diagnosis and Management
- Interprofessional Education and Collaboration
- Drug-Induced Hepatotoxicity and Protection
University of Colorado Denver
2016-2025
University of Montana
2016-2025
University of Colorado Anschutz Medical Campus
2016-2025
American College of Clinical Pharmacy
2006-2024
Meridian Clinical Research
2023
Olympic Park Sports Medicine Centre
2023
The Medical Center of Aurora
2014-2022
American Association of Colleges of Pharmacy
2022
Denver Health Medical Center
2021
Health and Hospital Corporation
2021
Although statins are generally well tolerated, statin intolerance is reported in 5-30% of patients and contributes to reduced adherence persistence, as higher risk for adverse cardiovascular outcomes. This Scientific Statement from the National Lipid Association was developed provide an updated definition inform clinicians researchers about its identification management. Statin defined one or more effects associated with therapy which resolves improves dose reduction discontinuation can be...
Expected treatment effectiveness from medications can be diminished due to suboptimal adherence. Medication nonadherence has been linked pill burden the quantity of medications; however, medication regimens with similar quantities vary in complexity multiple dosage forms, frequency dosing, and additional usage directions. Thus, a simple count ignores regimen complexity, especially as it pertains patient-level perspective that includes prescription over-the-counter medications. A gap exists...
The purpose of the American College Clinical Pharmacy ( ACCP ) is to advance human health by extending frontiers clinical pharmacy. Consistent with this mission and its core values, committed ensuring that pharmacists possess knowledge, skills, attitudes, behaviors necessary deliver comprehensive medication management CMM in team‐based, direct patient care environments. These components form basis for competencies a pharmacist reflect other providers. This paper an update previous document...
Blood pressure (BP) control rates among US adults taking antihypertensive medication have not increased over the past decade. Many require 2 or more classes of to achieve guideline-recommended BP goals, but proportion monotherapy, versus combination therapy, has been quantified using contemporary data. We analyzed data from 2005 2008, 2009 2012, and 2013 2016 National Health Nutrition Examination Surveys determine trends in monotherapy combinations age ≥20 years with hypertension (n=7837)....
An Expert Panel convened by the National Lipid Association was charged with updating recommendations on use of proprotein convertase subtilisin/kexin type 9 (PCSK9) antibody therapy that were provided 2015 Recommendations for Patient-Centered Management Dyslipidemia: Part 2. Recent studies have demonstrated efficacy these agents in reducing low-density lipoprotein cholesterol and non-high-density confirmed their excellent safety profile. A cardiovascular outcomes study has shown reduce...
ABSTRACT The risk of atherosclerotic cardiovascular disease increases with advancing age. Elevated LDL‐cholesterol and non‐HDL‐cholesterol levels remain predictive incident events among individuals older than 75 years. Risk prediction is less certain because most current calculators lack specificity in those years do not adjust for co‐morbidities, functional status, frailty, cognition which significantly impact prognosis this age group. Data on the benefits risks lowering statins patients...
This prospective, randomized, controlled study evaluated the impact of pharmacist‐initiated home blood pressure monitoring and intervention on control, therapy compliance, quality life (QOL). Subjects were 36 patients with uncontrolled stage 1 or 2 hypertension. Eighteen subjects received monitors, a diary, instructions to measure twice every morning. Home measurements by clinical pharmacist telephone, patient's family physician was contacted recommendations if mean monthly values 140/90 mm...
Although hypertension is a major risk factor for cardiovascular disease, adherence to hypertensive medications low. Previous research identifying factors influencing has focused primarily on broad, population-based approaches. Identifying specific barriers an individual more useful in designing meaningful targeted interventions. Using customized telephonic outreach, we examined patient-reported patients' nonadherence medication order identify interventions.A telephone survey of 8692...
Data describing the use of recommended antihypertensive agents in resistant hypertension population are limited. Treatment recommendations for include maximizing diuretic therapy by using chlorthalidone and/or adding an aldosterone antagonist. Additional combining from different drug classes. This retrospective cohort study describes patients with defined as concurrent ≥4 agents. Claims data Medstat MarketScan Commercial and Encounter database were used to identify based on International...
Importance Poor medication adherence is common. Text messaging increasingly used to change patient behavior but often not rigorously tested. Objective To compare different types of text strategies with usual care improve refill among patients nonadherent cardiovascular medications. Design, Setting, and Participants Patient-level randomized pragmatic trial between October 2019 April 2022 at 3 US health systems, last follow-up date 11, 2023. Adult (18 <90 years) were eligible based...
Receptor binding studies suggest that combinations of calcium channel blockers may result in either enhanced or diminished pharmacological effects, but clinical data hypertension are incomplete. In this study, we compared blood pressure reductions using nifedipine alone, plus diltiazem, and verapamil determined whether alter pharmacokinetics. After determination baseline pressures, 16 subjects with essential (12 men, 4 women; mean age, 48 years) received 30 mg/d open-label, sustained release...