A5031754632- Global Maternal and Child Health
- Maternal and Perinatal Health Interventions
- Maternal and fetal healthcare
- Delphi Technique in Research
- Grief, Bereavement, and Mental Health
- Palliative Care and End-of-Life Issues
- Global Health Workforce Issues
- Pregnancy and preeclampsia studies
- Geriatric Care and Nursing Homes
- Global Health and Surgery
- Maternal Mental Health During Pregnancy and Postpartum
- Emergency and Acute Care Studies
- Maternal and Neonatal Healthcare
- Trauma and Emergency Care Studies
- Ectopic Pregnancy Diagnosis and Management
- Pregnancy-related medical research
- COVID-19 Impact on Reproduction
- Reproductive Health and Contraception
- Sepsis Diagnosis and Treatment
- Child Nutrition and Water Access
- Patient-Provider Communication in Healthcare
- Appreciative Inquiry and Organizational Change
- Surgical site infection prevention
- Cardiac Arrest and Resuscitation
- Cardiac, Anesthesia and Surgical Outcomes
University of Bristol
2015-2025
University of Liverpool
2019-2025
Liverpool Women's Hospital
2022-2025
Liverpool Womens NHS Foundation Trust
2023-2025
North Bristol NHS Trust
2015-2024
University of Oxford
2024
Cardiff University
2024
Imperial College London
2024
Liverpool Heart and Chest Hospital
2024
Liverpool John Moores University
2024
Local settingMaternal mortality in Zimbabwe has increased from 555 to 960 per 100 000 live births 2006 2011 and a national review of maternal deaths deemed that 47% were avoidable. 7pilo Central Hospital is public, tertiary referral hospital Zimbabwe's second largest city, Bulawayo.Mpilo manages approximately 10 year provides all the services defined by World Health Organization's (WHO's) comprehensive emergency obstetric care services.These include administering antibiotics, uterotonic...
Background Postpartum haemorrhage (PPH) is the leading cause of maternal mortality worldwide. Prophylactic uterotonic drugs can reduce blood loss and are routinely recommended. There several for preventing PPH, but it still debatable which drug or combination most effective. Objectives To identify effective cost-effective drug(s) to prevent generate a ranking according their effectiveness side-effect profile. Methods The Cochrane Pregnancy Childbirth’s Trials Register (1 June 2015),...
Our objective was to codesign, implement, evaluate acceptability and refine an optimised antenatal education session improve birth preparedness.
Background Despite strong evidence-based strategies for prevention and management, global efforts to reduce deaths from postpartum haemorrhage (PPH) have failed, it remains the leading cause of maternal mortality. We conducted a detailed review all 33 facilities in Malawi identify health system weaknesses PPH. Methods Data were collected regarding every death occurring across district central hospitals Malawi. Deaths August 2020 December 2022 reviewed by multidisciplinary facility-based...
Objective: To identify which risk communication graphics are easiest to understand when communicating risks surrounding birth; and investigate the effect of numeracy health literacy on understanding. Design: Online survey with randomised content Setting: UK Population: Women their partners, healthcare professionals stakeholders in UK. Methods: Seven candidate ('10-person', '100-person', '10-circle', '100-circle' icon arrays, 'bar charts', 'pie charts' 'words') were co-produced a patient...
Induction of labour (IOL) is a common obstetric intervention in the UK, affecting up to 33% deliveries. IOL aims achieve vaginal delivery prior spontaneous onset prevent harm from ongoing pregnancy complications and known stillbirths reduce neonatal intensive care unit admissions. However, doesn't come without risk overall, 20% mothers having an induction will still require caesarean section birth primiparous this rate even higher. There no reliable predictive bedside tool available clinical...
Abstract Introduction Antenatal education (ANE) equips pregnant women with knowledge and skills for pregnancy, birth, the postnatal period. It should facilitate preparation whole spectrum of maternal journey empower to make informed decisions. This study aimed explore antenatal needs preferences who are currently or planning a pregnancy. Methods A UK wide cross-sectional survey was conducted (September 2019 July 2020), recruiting living in UK, above 16, were The gathered demographic...
Introduction Neonatal death exerts long-lasting impact on parents’ mental health, finances and relationships, the wider family. There is national international momentum to evaluate interventions support parents after of a baby. Core Outcome Sets (COSs) provide minimum set outcomes, agreed by stakeholders be important, which should evaluated in all studies evidence syntheses identification most effective interventions. We aim develop COS for assessing care neonatal high-income countries,...
Cellular senescence is a well-established biological phenomenon in eukaryotes. It involves DNA damage, telomere shortening, senescence-associated secretory phenotype (SASP), and the inability of cells to replicate. associated with ageing, also oxidative stress. Given importance stress pre-eclampsia, there considerable evidence, that we review, plays an important role both normal placental development early- late-term pre-eclampsia. Autophagy capable delaying or even reversing senescence,...
A combination of mifepristone and a prostaglandin preparation should usually be recommended as the first-line intervention for induction labour (Grade B). single 200 milligram dose is appropriate this indication, followed by: 24
Caesarean section (CS) is the most common major surgery conducted globally, with rates rising. CS also contributes to maternal morbidity and mortality, increased risks in low-resource settings. We a detailed review of deaths from 2020 2022 Malawi determine burden related CS, avoidable health system factors, causes death associated this procedure.
Globalisation is having profound impacts on health and healthcare. We solicited the views of a wide range stakeholders in order to develop core global competencies for postgraduate doctors.Published literature existing curricula informed writing seven consultation. A modified policy Delphi involved an online survey face-to-face telephone interviews over three rounds.Over 250 participated, including doctors, other professionals, policymakers members public from all continents world....
Surgical intervention is needed in some cases of spontaneous abortion to remove retained products conception. Antibiotic prophylaxis may reduce the risk pelvic infection, which an important complication this surgery, particularly low-resource countries.
The objective of this study was to estimate the relative cost effectiveness for full range uterotonic drugs available preventing postpartum haemorrhage (PPH). A model-based economic evaluation constructed using data from a network meta-analysis, and supplemented by literature. UK National Health Service (NHS) perspective adopted analysis, which is based on costs published sources. primary outcome measure per case PPH avoided (≥ 500 mL blood loss), with secondary measures severe 1000 mL)...