A5015911521- Ectopic Pregnancy Diagnosis and Management
- Maternal and fetal healthcare
- Maternal and Perinatal Health Interventions
- Assisted Reproductive Technology and Twin Pregnancy
- Reproductive System and Pregnancy
- Pregnancy and Medication Impact
- Grief, Bereavement, and Mental Health
- Uterine Myomas and Treatments
- Bacterial Infections and Vaccines
- Endometriosis Research and Treatment
- Aerospace and Aviation Technology
- Pregnancy and preeclampsia studies
- Pneumonia and Respiratory Infections
- Family Support in Illness
- Delphi Technique in Research
- Global Maternal and Child Health
- Air Traffic Management and Optimization
- Prenatal Screening and Diagnostics
- Pregnancy-related medical research
- Nursing Diagnosis and Documentation
- Inhalation and Respiratory Drug Delivery
- Health Sciences Research and Education
- Sleep and Work-Related Fatigue
- Gender Roles and Identity Studies
- Focus Groups and Qualitative Methods
Lucile Packard Children's Hospital
2024
University of Vienna
2024
Taylor Wimpey (United Kingdom)
2024
Taylor and Francis (United Kingdom)
2024
Science Oxford
2024
Artificial Intelligence in Medicine (Canada)
2024
Kings Health Partners
2024
University College London
2024
Cardiff University
2021-2023
University of Liverpool
2020
Progesterone is essential for the maintenance of pregnancy. However, whether progesterone supplementation in first trimester pregnancy would increase rate live births among women with a history unexplained recurrent miscarriages uncertain.
Bleeding in early pregnancy is strongly associated with loss. Progesterone essential for the maintenance of pregnancy. Several small trials have suggested that progesterone therapy may improve outcomes women who bleeding pregnancy.We conducted a multicenter, randomized, double-blind, placebo-controlled trial to evaluate progesterone, as compared placebo, vaginal Women were randomly assigned receive suppositories containing either 400 mg or matching placebo twice daily, from time at which...
Background and objectives Progesterone is essential to maintain a healthy pregnancy. Guidance from the Royal College of Obstetricians Gynaecologists Cochrane review called for definitive trial test whether or not progesterone therapy in first trimester could reduce risk miscarriage women with history unexplained recurrent (RM). The PROMISE was conducted answer this question. A concurrent cost-effectiveness analysis conducted. Design setting randomised, double-blind, placebo-controlled,...
Background Postpartum haemorrhage (PPH) is the leading cause of maternal mortality worldwide. Prophylactic uterotonic drugs can reduce blood loss and are routinely recommended. There several for preventing PPH, but it still debatable which drug or combination most effective. Objectives To identify effective cost-effective drug(s) to prevent generate a ranking according their effectiveness side-effect profile. Methods The Cochrane Pregnancy Childbirth’s Trials Register (1 June 2015),...
Background Progesterone is essential for a healthy pregnancy. Several small trials have suggested that progesterone therapy may rescue pregnancy in women with early bleeding, which symptom strongly associated miscarriage. Objectives (1) To assess the effects of vaginal micronised bleeding first 12 weeks (2) evaluate cost-effectiveness bleeding. Design A multicentre, double-blind, placebo-controlled, randomised trial Setting total 48 hospitals UK. Participants Women aged 16–39 years...
The objective of this study was to estimate the relative cost effectiveness for full range uterotonic drugs available preventing postpartum haemorrhage (PPH). A model-based economic evaluation constructed using data from a network meta-analysis, and supplemented by literature. UK National Health Service (NHS) perspective adopted analysis, which is based on costs published sources. primary outcome measure per case PPH avoided (≥ 500 mL blood loss), with secondary measures severe 1000 mL)...
Approximately one in four pregnancies result pregnancy loss, and ~50% of these miscarriages are caused by chromosomal abnormalities. Genetic investigations recommended after three consecutive on products conception (POC) tissue. Cell-free DNA (cfDNA) has been utilised for prenatal screening, but very little work carried out nonviable pregnancies. We investigated the use cfDNA from maternal blood to identify abnormalities miscarriage. One hundred two samples women experiencing a first...
To identify the needs, experiences and preferences of women with kidney disease in relation to their reproductive health inform development shared decision-making interventions.UK-wide mixed-methods convergent design (Sep 20-Aug 21).Online questionnaire (n = 431) validated components. Purposively sampled semi-structured interviews 30). Patient public input throughout.Kidney was associated defeminization, negatively affecting current (sexual) relationships perceptions future life goals. There...
One in four pregnancies ends miscarriage, a distressing event which can cause significant psychosocial impacts for many women, and yet often remains unseen unspoken. Many would-be mothers turn to the internet information emotional support, share their experiences. In this paper, we present results from 12 semi-structured interviews with investigating how what online they searched at time of miscarriage. We found that women are passive seekers, searching causes preventive strategies inform...
Journal Article The prevalence of antibiotic resistance in Haemophilus influenzae Ireland Get access A. J. Howard, Howard Department Medical Microbiology, Gwynedd HospitalPenrhosgarnedd, Bangor, North Wales LL57 2PW, UK Search for other works by this author on: Oxford Academic PubMed Google Scholar H. M. Williams Antimicrobial Chemotherapy, Volume 24, Issue 6, December 1989, Pages 963–971, https://doi.org/10.1093/jac/24.6.963 Published: 01 1989
From January to April 1986 all 21 Clinical Microbiology Laboratories in Wales took part a survey determine the prevalence of antibiotic resistance Haemophilus influenzae. All isolates were collected and despatched central laboratory where identification was confirmed sensitivity tests repeated. One thousand four hundred forty strains available for analysis. Resistance present 128 (8.9%) ampicillin, 23 (1.6%) cefaclor, 28 (1.7%) chloramphenicol, 282 (19.6%) erythromycin, 43 (3.0%)...
Introduction Up to 1 in 4 pregnancies and 20 subsequent end miscarriage. Despite such prevalence the psychosocial effects are often unrecognised unsupported. In absence of any biomedical sequelae among men marginalisation may be intensified. Men living through multiple miscarriages also find grief or anxiety intensified by loss hope for future parenthood, but robust qualitative studies these experiences limited. We aim rectify deficiency. Methods analysis Our study will adopt sounds silence...
Standards to define and measure quality in healthcare for cardiovascular disease risk reduction secondary prevention are available, but there is a paucity of indicators that could serve as facilitators structural change at system level. This research study aimed develop range delivery help cardiac clinical networks assess progress towards objectives.
To report a protocol for qualitative study to better understand the key factors that influence decision making about pregnancy from women's perspectives and use these data develop theoretical model shared decision-making tools multiple stakeholders.Mixed-method design using online surveys (with validated components) purposively sampled follow-up semi structured interviews.Funded September 2020 12 months. Online of adult women (aged 18-50) identified via all Wales kidney database (n ≥ 500),...
( N Engl J Med . 2019;380(19):1815–1824) This study aimed to determine whether the controversial use of progesterone therapy in women with early bleeding pregnancy could result a higher incidence live births than placebo. It was multicenter, randomized, double-blind, placebo-controlled trial evaluate progesterone, as compared placebo, vaginal pregnancy. Women received suppositories or from presentation 16 weeks if helps improve outcomes for
The Federal Aviation Administration (FAA) and general aviation (GA) industry are working collaboratively to publish lower minimum en route altitudes (MEAs) for Global Positioning System (GPS)-equipped aircraft operating at low altitudes, more direct transition routes through Class B airspace based on area navigation (RNAV) (commonly achieved in GA with GPS). These efforts intended improve access airspace, safety of flight, seamless RNAV operations the NAS - accordance FAA's roadmap...