D. Lissauer
A5086573584- Particle physics theoretical and experimental studies
- High-Energy Particle Collisions Research
- Quantum Chromodynamics and Particle Interactions
- Particle Detector Development and Performance
- Dark Matter and Cosmic Phenomena
- Global Maternal and Child Health
- Maternal and fetal healthcare
- Maternal and Perinatal Health Interventions
- Nuclear physics research studies
- Neutrino Physics Research
- Radiation Detection and Scintillator Technologies
- Cosmology and Gravitation Theories
- Reproductive System and Pregnancy
- Sepsis Diagnosis and Treatment
- Trauma and Emergency Care Studies
- Particle Accelerators and Free-Electron Lasers
- Pregnancy and Medication Impact
- COVID-19 Impact on Reproduction
- Computational Physics and Python Applications
- Astrophysics and Cosmic Phenomena
- Neonatal and Maternal Infections
- Nuclear reactor physics and engineering
- Muon and positron interactions and applications
- Atomic and Molecular Physics
- Pregnancy and preeclampsia studies
Malawi-Liverpool-Wellcome Trust Clinical Research Programme
2019-2025
University of Liverpool
2019-2025
Liverpool Women's Hospital
2025
University of Malawi
2021-2024
Kamuzu University of Health Sciences
2023
University of Birmingham
2012-2023
Ministry of Health
2023
University of Health Science
2023
Liverpool School of Tropical Medicine
2023
Universidade de Pernambuco
2023
Delays in the detection or treatment of postpartum hemorrhage can result complications death. A blood-collection drape help provide objective, accurate, and early diagnosis hemorrhage, delayed inconsistent use effective interventions may be able to addressed by a bundle.
The status of the research on muon colliders is discussed and plans are outlined for future theoretical experimental studies. Besides continued work parameters a 3-4 0.5 TeV center-of-mass (CoM) energy collider, many studies now concentrating machine near 0.1 that could be factory s-channel production Higgs particles. We discuss various components in such colliders, starting from proton accelerator needed to generate pions heavy-Z target proceeding through phase rotation decay ($\pi \to \mu...
Tolerance of the semiallogeneic fetus presents a significant challenge to maternal immune system during human pregnancy. T cells with specificity for fetal epitopes have been detected in women history previous pregnancy, but it has thought that such fetal-specific were generally deleted pregnancy as mechanism maintain tolerance fetus. We used MHC-peptide dextramer multimers containing an immunodominant peptide derived from HY identify who pregnant male Fetal-specific CD8(+) lymphocytes...
Maternal infections are an important cause of maternal mortality and severe morbidity. We report the main findings WHO Global Sepsis Study, which aimed to assess frequency in health facilities, according characteristics outcomes, coverage core practices for early identification management.We did a facility-based, prospective, 1-week inception cohort study 713 facilities providing obstetric, midwifery, or abortion care, where women could be admitted because complications pregnancy,...
Progesterone is a steroid hormone essential for the maintenance of human pregnancy, and its actions are thought to include promoting maternal immune tolerance semiallogenic fetus. We report that exposure T cells progesterone at physiological doses induced unique skewing cytokine production profile CD4 + CD8 cells, with reductions not only in potentially deleterious IFN‐γ TNF‐α but also IL‐10 IL‐5. Conversely, IL‐4 was increased. Maternal became less polyfunctional, focussing toward profiles...
Abstract Objective To systematically develop evidence‐based bundles for care of postpartum hemorrhage ( PPH ). Methods An international technical consultation was conducted in 2017 to draft clinical interventions taken from the WHO 's 2012 and recommendations based on validated “ GRADE Evidence‐to‐Decision” framework. Twenty‐three global maternal‐health experts participated development process, which informed by a systematic literature search bundle definitions, designs, implementation...
In 1972, two landmark papers in this journal described the partograph,1, 2 a chart designed to provide finite referral criteria for midwives working peripheral clinics who needed refer women labour Harare Hospital, Zimbabwe (then Rhodesia). This innovation coincided with influential reports from National Maternity Hospital Dublin of 'active management labour' (early amniotomy, proactive use oxytocin and one-to-one nursing care) objective achieving birth within limited time frame.3 The...
Abstract Immune tolerance during human pregnancy is maintained by a range of modifications to the local and systemic maternal immune system. Lymphoid infiltration seen at implantation site fetal–maternal interface, decidual NK cells have been demonstrated facilitate extravillous trophoblast invasion into decidua first trimester, optimizing hemochorial placentation. However, although there considerable T cell decidua, functional properties this response remain poorly defined. We investigated...
We have measured the differential cross section for reaction ${K}^{+}n\ensuremath{\rightarrow}{K}^{0}p$ at 12 $\frac{\mathrm{GeV}}{c}$. find that (1) forward amplitude is essentially real, (2) equals ${K}^{\ensuremath{-}}p\ensuremath{\rightarrow}{K}^{0}n$, and (3) agrees well with predictions of Regge-pole model Rarita Schwarzschild. also compiled data on ${K}^{+}n$ charge-exchange as a function incident momentum, compared it...
Does administration of recombinant human granulocyte colony stimulating factor (rhG-CSF) in the first trimester improve pregnancy outcomes, among women with a history unexplained recurrent loss? rhG-CSF administered did not outcomes loss. The only previous randomized controlled study miscarriage 68 primary found statistically significant reduction and improvement live birth rates. A further four observational studies where G-CSF was used population were identified literature, two which...