- Ectopic Pregnancy Diagnosis and Management
- Maternal and fetal healthcare
- Uterine Myomas and Treatments
- Reproductive Health and Contraception
- Endometriosis Research and Treatment
- Gynecological conditions and treatments
- Gestational Trophoblastic Disease Studies
- Hernia repair and management
- Ovarian function and disorders
- Maternal and Perinatal Health Interventions
- Reproductive System and Pregnancy
- Appendicitis Diagnosis and Management
- Reproductive Biology and Fertility
- Breast Cancer Treatment Studies
- Homicide, Infanticide, and Child Abuse
- Diverticular Disease and Complications
- Diagnosis and treatment of tuberculosis
- Pregnancy-related medical research
- Lung Cancer Diagnosis and Treatment
- Hemostasis and retained surgical items
- Minimally Invasive Surgical Techniques
- Breast Lesions and Carcinomas
- Pregnancy and Medication Impact
- Pregnancy and preeclampsia studies
- Hormonal and reproductive studies
Whipps Cross University Hospital
2009-2023
Barts Health NHS Trust
2013-2021
Royal London Hospital
2013-2021
Mayo General Hospital
2021
University of Birmingham
2019
Miscarriage Association
2019
University College London
2007-2013
Whittington Hospital
2007
Bleeding in early pregnancy is strongly associated with loss. Progesterone essential for the maintenance of pregnancy. Several small trials have suggested that progesterone therapy may improve outcomes women who bleeding pregnancy.We conducted a multicenter, randomized, double-blind, placebo-controlled trial to evaluate progesterone, as compared placebo, vaginal Women were randomly assigned receive suppositories containing either 400 mg or matching placebo twice daily, from time at which...
BackgroundThe anti-progesterone drug mifepristone and the prostaglandin misoprostol can be used to treat missed miscarriage. However, it is unclear whether a combination of more effective than administering alone. We investigated treatment with plus would result in higher rate completion miscarriage compared alone.MethodsMifeMiso was multicentre, double-blind, placebo-controlled, randomised trial 28 UK hospitals. Women were eligible for enrolment if they aged 16 years older, diagnosed by...
Background Progesterone is essential for a healthy pregnancy. Several small trials have suggested that progesterone therapy may rescue pregnancy in women with early bleeding, which symptom strongly associated miscarriage. Objectives (1) To assess the effects of vaginal micronised bleeding first 12 weeks (2) evaluate cost-effectiveness bleeding. Design A multicentre, double-blind, placebo-controlled, randomised trial Setting total 48 hospitals UK. Participants Women aged 16–39 years...
To assess the cost-effectiveness of mifepristone and misoprostol (MifeMiso) compared with only for medical management a missed miscarriage.Within-trial economic evaluation model-based analysis to set findings in context wider evidence range comparators. Incremental costs outcomes were calculated using nonparametric bootstrapping reported acceptability curves. Analyses performed from perspective UK's National Health Service (NHS).Twenty-eight UK NHS early pregnancy units.A cohort 711 women...
Interstitial pregnancy is a rare type of ectopic pregnancy; it tends to present late, most commonly missed, and associated with significant maternal morbidity mortality. Early clinical diagnosis aided by ultrasound laparoscopy may help contribute towards effective conservative or fertility preserving treatment modalities thereby reduce potential We case missed interstitial in an inner city London hospital, where the diagnostic accuracy published as high 90%, aim analyzing difficulties...
Objectives To assess the cost‐effectiveness of progesterone compared with placebo in preventing pregnancy loss women early vaginal bleeding. Design Economic evaluation alongside a large multi‐centre randomised placebo‐controlled trial. Setting Forty‐eight UK NHS units. Population Four thousand one hundred and fifty‐three aged 16–39 years bleeding ultrasound evidence an intrauterine sac. Methods An incremental analysis was performed from National Health Service (NHS) Personal Social Services...
Trial design A randomised, parallel-group, double-blind, placebo-controlled multicentre study with health economic and nested qualitative studies to determine if mifepristone (Mifegyne ® , Exelgyn, Paris, France) plus misoprostol is superior alone for the resolution of missed miscarriage. Methods Women diagnosed miscarriage in first 14 weeks pregnancy were randomly assigned (1 : 1 ratio) receive 200 mg oral or matched placebo, followed by 800 μg 2 days later. web-based randomisation system...
A caesarean scar pregnancy (CSP) is a that implants into the myometrium at site of previous uterine incision.In this paper, we present three cases women affected by implantations.Each case presented differently and was managed in separate ways.We describe their differing presentations care as well reflecting on how such may be better cared for.Endogenic CSPs grow cavity can easily mistaken for normal implantation.Differentiation often only seen early gestations.All with should potentially...
Background: It’s a miscarriage in which the fetus didn’t form or is no longer developing, but placenta and embryonic tissues are still uterus. Objectives: To identify risk factors that women miss abortions. find out association between Risk for missed abortion demographic characteristics of women. Methodology: Descriptive study design was conducted though present period from 25/November/2022 end 1/February/2023. The self-administrative report procedure designed questionnaire were used to...
( N Engl J Med . 2019;380(19):1815–1824) This study aimed to determine whether the controversial use of progesterone therapy in women with early bleeding pregnancy could result a higher incidence live births than placebo. It was multicenter, randomized, double-blind, placebo-controlled trial evaluate progesterone, as compared placebo, vaginal pregnancy. Women received suppositories or from presentation 16 weeks if helps improve outcomes for
Background: Ipsilateral recurrence after salpingectomy is rare, but delay in diagnosis can result rupture and potentially life-threatening hemorrhaging. Because of the paucity data, there are various methods by which ipsilateral recurrent ectopic pregnancies have been managed. It may be possible to decrease incidence such further with complete removal Fallopian tubes at primary surgery. Case: This article presents a rare case repeat pregnancy distal remnant part tube following laparoscopic...
To study the various ultrasound features of ectopic pregnancy in relation to management option. A three year prospective cohort sonomorphologic was conducted from January 2009 December 2011. All women with suspected ectopics were enrolled consecutively into study, evaluated ultrasonography, and based on patient's symptoms. Ultrasonographic extrauterine classified five categories; 1) Gestational sac alone (bagel sign), 2) GS an embryo but no heart rate, 3) a yolk sac, 4) Inhomogeneous mass...
To evaluate the ultrasound and laparoscopic diagnosis management of non-tubal ectopic pregnancy. This was a prospective cohort data analysis all women with pregnancies managed medically or surgically between January 2000 December 2011. A total 800 had pregnancies. Fifty (50) consist 29 uterine interstitial (cornual), 17 ovarian, 2 Caesarean scar abdominal were diagnosed during study period. All patients underwent transvaginal scan. Patient characteristics socio-demography, symptoms stable...
To evaluate the diagnostic accuracy of Ultrasound in diagnosis ectopic pregnancy compared to operative findings women undergoing surgical management. Prospective observational study a University hospital 6444 consecutive who underwent ultrasound for early problems 2008 and 2009. Data was collected from astria database evaluation clinical notes. Excel spreadsheet used data analysis. 138 diagnosed with on pelvic management, features were histological diagnosis. Ectopic TAS/TVS if one or more...