Abigail Oliver
- Ectopic Pregnancy Diagnosis and Management
- Reproductive Health and Contraception
- Maternal and Perinatal Health Interventions
- Pregnancy and Medication Impact
- SARS-CoV-2 and COVID-19 Research
- Respiratory viral infections research
- Psychiatric care and mental health services
- Schizophrenia research and treatment
- Mental Health and Patient Involvement
- SARS-CoV-2 detection and testing
- Ovarian cancer diagnosis and treatment
University College London
2023
National Hospital for Neurology and Neurosurgery
2023
St Michael's Hospital
2020-2021
University Hospitals Bristol NHS Foundation Trust
2020-2021
St Michael’s Hospital
2020-2021
St Michaels Hospital
2020-2021
BackgroundThe anti-progesterone drug mifepristone and the prostaglandin misoprostol can be used to treat missed miscarriage. However, it is unclear whether a combination of more effective than administering alone. We investigated treatment with plus would result in higher rate completion miscarriage compared alone.MethodsMifeMiso was multicentre, double-blind, placebo-controlled, randomised trial 28 UK hospitals. Women were eligible for enrolment if they aged 16 years older, diagnosed by...
To assess the cost-effectiveness of mifepristone and misoprostol (MifeMiso) compared with only for medical management a missed miscarriage.Within-trial economic evaluation model-based analysis to set findings in context wider evidence range comparators. Incremental costs outcomes were calculated using nonparametric bootstrapping reported acceptability curves. Analyses performed from perspective UK's National Health Service (NHS).Twenty-eight UK NHS early pregnancy units.A cohort 711 women...
Trial design A randomised, parallel-group, double-blind, placebo-controlled multicentre study with health economic and nested qualitative studies to determine if mifepristone (Mifegyne ® , Exelgyn, Paris, France) plus misoprostol is superior alone for the resolution of missed miscarriage. Methods Women diagnosed miscarriage in first 14 weeks pregnancy were randomly assigned (1 : 1 ratio) receive 200 mg oral or matched placebo, followed by 800 μg 2 days later. web-based randomisation system...