Alejandra de Moreno de LeBlanc

ORCID: 0000-0003-0352-374X
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About
Contact & Profiles
Research Areas
  • Probiotics and Fermented Foods
  • Gut microbiota and health
  • Digestive system and related health
  • Infant Nutrition and Health
  • Microbial Metabolites in Food Biotechnology
  • Viral gastroenteritis research and epidemiology
  • Cancer Research and Treatments
  • Protein Hydrolysis and Bioactive Peptides
  • Parkinson's Disease Mechanisms and Treatments
  • Diet and metabolism studies
  • Clostridium difficile and Clostridium perfringens research
  • Food composition and properties
  • Oral health in cancer treatment
  • Gastrointestinal motility and disorders
  • Immune Response and Inflammation
  • Child Nutrition and Feeding Issues
  • Nutrition, Genetics, and Disease
  • Antimicrobial Peptides and Activities
  • IL-33, ST2, and ILC Pathways
  • Pediatric health and respiratory diseases
  • Helicobacter pylori-related gastroenterology studies
  • Alzheimer's disease research and treatments
  • Mycotoxins in Agriculture and Food
  • Alcoholism and Thiamine Deficiency
  • Cancer, Stress, Anesthesia, and Immune Response

Consejo Nacional de Investigaciones Científicas y Técnicas
2015-2025

Centro Científico Tecnológico - Tucumán
2014-2024

Centro Científico Tecnológico - San Juan
2016

Microbiologie de l’alimentation au service de la santé
2014

National University of Tucumán
2002-2007

Université de Moncton
2005-2007

Abstract Background Diarrheal infections caused by Salmonella , are one of the major causes childhood morbidity and mortality in developing countries. various diseases that range from mild gastroenteritis to enteric fever, depending on serovar involved, infective dose, species, age immune status host. Probiotics proposed as an attractive alternative possibility prevention against this pathogen infection. Previously we demonstrated continuous Lactobacillus casei CRL 431 administration BALB/c...

10.1186/1471-2180-11-177 article EN cc-by BMC Microbiology 2011-08-03

Lactic acid bacteria (LAB) represent a heterogeneous group of microorganisms that are naturally present in many foods and possess wide range therapeutic properties. The aim this paper is to an overview the current expanding knowledge one mechanisms by which LAB other probiotic participate prevention treatment gastrointestinal inflammatory disease through their immune-modulating A special emphasis will be placed on critical role anti-inflammatory cytokine IL-10, brief uses genetically...

10.5402/2011/892971 article EN ISRN Gastroenterology 2011-02-08

Fibre content, phenolic antioxidant and anti-inflammatory activities were evaluated for water extracts of fruit by-products (passion fruit, orange, acerola, mango). The impact these on microbial growth, folate production, adhesion ability Streptococcus thermophilus TH-4 Lactobacillus rhamnosus LGG was investigated. Mango extract (MWE) presented the highest content activity. Orange (OWE) MWE showed best potential by decreasing nitric oxide levels. When grown together, production only...

10.1016/j.jff.2018.12.002 article EN publisher-specific-oa Journal of Functional Foods 2018-12-15

Reactive oxygen species, such as hydrogen peroxide (H2O2), are involved in various aspects of tumour development. Decreasing their levels can therefore be a promising approach for colon cancer prevention. The objective this study was to evaluate the effect catalase-producing Lactococcus lactis on prevention an experimental murine 1,2-dimethylhydrazine (DMH)-induced cancer. DMH-treated BALB/c mice received either L. strain or isogenic non-catalase-producing control, whereas other untreated...

10.1099/jmm.0.47403-0 article EN Journal of Medical Microbiology 2007-12-07

Lactic acid bacteria are present in many foods such as yoghurt and frequently used probiotics to improve some biological functions of the host. Many researchers have evaluated effects lactic against diseases cancer intestinal inflammation. The preventive effect on carcinogenesis may be associated with changes microbiota, suppressing growth that convert procarcinogens into carcinogens. Other mechanisms could related immune response modulation been using milks fermented chemically induced...

10.1017/s002966511000159x article EN Proceedings of The Nutrition Society 2010-06-16

ABSTRACT The aims of this study were to develop strains lactic acid bacteria (LAB) having both immunomodulatory and antioxidant properties evaluate their anti-inflammatory effects in vitro , different cellular models, vivo a mouse model colitis. Different Lactobacillus delbrueckii subsp. bulgaricus Streptococcus thermophilus cocultured with primary cultures mononuclear cells. Analysis the pro- cytokines secreted by these cells after coincubation candidate revealed that L. CRL 864 S. 807...

10.1128/aem.03296-13 article EN Applied and Environmental Microbiology 2013-11-16

Abstract Background Malnutrition affects the immune response, causing a decrease of defence mechanisms and making host more susceptible to infections. Probiotics can reconstitute intestinal mucosa stimulate local systemic immunity. The aim this work was evaluate effects probiotic fermented milk as complement re-nutrition diet, on recovery barrier, mucosal functions in murine model non-severe protein-energy-malnutrition. Its potential protection against Salmonella enterica serovar Typhimurium...

10.1186/1471-230x-11-64 article EN cc-by BMC Gastroenterology 2011-05-26

Breast cancer is the second cause of death in women, who are especially related to uncontrolled metastasis. It was previously demonstrated that administration milk fermented by Lactobacillus casei CRL 431 [fermented (FM)] delayed tumor growth a murine breast model. In this work we evaluated if FM mice, starting when measurable, can affect not only growth, but also extravasation cells and lung The evaluation immune cells–infiltrating tumors lungs performed. Tumor volume calculated. Whole...

10.1097/cji.0000000000000079 article EN Journal of Immunotherapy 2015-05-08

Abstract Introduction Antitumour activity is one of the health-promoting effects attributed to lactic acid bacteria and their products fermentation. Previous studies in mice demonstrated that bioactive compounds released milk fermented by Lactobacillus helveticus R389 contribute its immunoenhancing antitumour properties. The aim present work was study consumption L. or proteolytic-deficient variant, L89, on a murine hormone-dependent breast cancer model. Methods Mice were fed with during 2 7...

10.1186/bcr1032 article EN cc-by Breast Cancer Research 2005-04-26

Abstract Background Microbial colonization of the intestine after birth is an important step for development gut immune system. The acquisition passive immunity through breast-feeding may influence pattern bacterial in newborn. aim this work was to evaluate effect administration a probiotic fermented milk (PFM) containing yogurt starter cultures and bacteria strain Lactobacillus casei DN-114001 mothers during nursing or their offspring, on intestinal population parameters Results Fifteen...

10.1186/1471-2172-9-27 article EN cc-by BMC Immunology 2008-06-13
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