Mingzhong Sun

ORCID: 0000-0003-0356-666X
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About
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Research Areas
  • Carbon and Quantum Dots Applications
  • RNA modifications and cancer
  • Vibrio bacteria research studies
  • S100 Proteins and Annexins
  • Selenium in Biological Systems
  • Nanoparticle-Based Drug Delivery
  • Escherichia coli research studies
  • Heat shock proteins research
  • Bone Tissue Engineering Materials
  • Ubiquitin and proteasome pathways
  • Lung Cancer Research Studies
  • Cell Adhesion Molecules Research
  • Cleft Lip and Palate Research
  • MicroRNA in disease regulation
  • Luminescence and Fluorescent Materials
  • Pediatric health and respiratory diseases
  • Insect behavior and control techniques
  • Connective tissue disorders research
  • Oral and Craniofacial Lesions
  • Nosocomial Infections in ICU
  • Advanced Nanomaterials in Catalysis
  • Enterobacteriaceae and Cronobacter Research
  • Genomics and Chromatin Dynamics
  • Bacterial Genetics and Biotechnology
  • Microtubule and mitosis dynamics

Yancheng Third People's Hospital
2009-2021

Anhui Normal University
2018-2021

Dalian Medical University
2014

X-ray computed tomography (CT) is the most commonly used imaging technique for noninvasive diagnosis of disease. In order to improve tissue specificity and prevent adverse effects, we report design synthesis iodine-doped carbon dots (I-doped CDs) as efficient CT contrast agents fluorescence probe by a facile bottom-up hydrothermal carbonization process. The as-prepared I-doped CDs are monodispersed spherical nanoparticles (a diameter ~2.7 nm) with favorable dispersibility colloidal stability...

10.2147/ijn.s82778 article EN cc-by-nc International Journal of Nanomedicine 2015-11-01

Abstract Although proper tongue development is relevant to other structures in the craniofacial region, molecular details of muscle remain poorly understood. Here, we report that pregnant mice treated with retinoic acid (+RA) produce embryos malformation and a cleft palate. Histological analyses revealed at E14.5, tongues +RA fetuses failed descend flatten. Ultrastructural analysis showed perinatal stage E18.5, myofilaments form normal sarcomeres arranged disorderly genioglossus. The...

10.1038/srep06082 article EN cc-by Scientific Reports 2014-08-15

Objective. To compare the clinical value of serum microRNA21 (miR21) and other tumor markers in early diagnosis non-small cell lung cancer (NSCLC). Methods. Serums carcinoembryonic antigen (CEA), cytokeratin 19 fragment (CYFRA21-1), neuron-specific enolase (NSE), miR21 were detected 50 NSCLC cases 60 healthy control individuals. Results. Average serums miR21, CEA, NSE, CYFRA21-1 levels significantly higher case group than (<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"...

10.1155/2016/3823121 article EN Disease Markers 2016-01-01

Ferroptosis as an iron-dependent lipid peroxidation process causes sevely oxidative damage of cell, but lack highly efficient and recycable antioxidant agents. To this end, cerium doped carbon dots (Ce-doped CDs) with radical scavenging activity were synthesized using a simple microwave-assisted hydrothermal carbonization. The resultant Ce-doped CDs exhibited ultra-small size only approximately 2.6 nm, excellent dispersion in water well optical performance. Taking advantage inherent size,...

10.1088/1361-6528/ac0dd9 article EN Nanotechnology 2021-06-23

The Drosophila testis provides an exemplary model for analyzing the extrinsic and intrinsic factors that regulate fate of stem cell in vivo. Using this model, we show αTub67C gene (full name αTubulin at 67C), which encodes α4-Tubulin (a type α-Tubulin), plays a new role controlling male germline cells (GSC). In study, have found is required intrinsically extrinsically GSCs maintenance. Results from green fluorescent protein (GFP)-transgene reporter assays not Dpp/Gbb signaling silencing bam...

10.1038/s41598-021-90116-7 article EN cc-by Scientific Reports 2021-05-20

To examine the differential expression pattern of Ech1 protein in mouse Hca-F and Hca-P hepatocarcinoma cell lines with high low rates lymphatic metastasis, respectively, to investigate relationships between adhesion cells. Fluorescence two-dimensional difference in-gel electrophoresis (2D DIGE) mass spectrometry were used detect expression. gene silencing was achieved by stable transfection cells a plasmid vector harboring short hairpin RNA (shRNA) targeting Ech1, pGPU6/GFP/Neo-shRNA-Ech1....

10.3760/cma.j.issn.1007-3418.2012.08.013 article EN PubMed 2012-08-01
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