Junyu Lu

ORCID: 0000-0003-0366-354X
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About
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Research Areas
  • Electromagnetic wave absorption materials
  • Advanced Antenna and Metasurface Technologies
  • Nanocomposite Films for Food Packaging
  • Flame retardant materials and properties
  • Metamaterials and Metasurfaces Applications
  • Microfluidic and Capillary Electrophoresis Applications
  • Electrospun Nanofibers in Biomedical Applications
  • biodegradable polymer synthesis and properties
  • Advanced Sensor and Energy Harvesting Materials
  • Advanced biosensing and bioanalysis techniques
  • Autophagy in Disease and Therapy
  • Postharvest Quality and Shelf Life Management
  • Analytical Chemistry and Chromatography
  • Synthesis and properties of polymers
  • Electrochemical Analysis and Applications
  • Graphene and Nanomaterials Applications
  • Transition Metal Oxide Nanomaterials
  • Gas Sensing Nanomaterials and Sensors
  • Synthesis and biological activity
  • Conducting polymers and applications
  • Cholesterol and Lipid Metabolism
  • Advanced Cellulose Research Studies
  • Solar Thermal and Photovoltaic Systems
  • Gout, Hyperuricemia, Uric Acid
  • Antimicrobial agents and applications

Sichuan University
2022-2024

Sichuan Agricultural University
2018-2021

Second Military Medical University
2018-2020

Guangxi Medical University
2020

Tiangong University
2017

Guangxi Normal University
2011-2013

Papworth Hospital
2013

University of Cambridge
2013

Tongji University
2010

Rationale: Pulmonary arterial hypertension (PAH) is characterized by excessive proliferation and apoptosis resistance in pulmonary artery smooth muscle cells (PASMCs). Objective: We reasoned that chloroquine, based on its ability to inhibit autophagy block lysosomal degradation of the bone morphogenetic protein type II receptor (BMPR-II), might exert beneficial effects this disease. Methods Results: PAH was induced male Sprague–Dawley rats administering monocrotaline. The induction...

10.1161/circresaha.111.300483 article EN Circulation Research 2013-02-28

Abstract This paper describes the development of silica monolith modified with bovine serum albumin–gold nanoparticles (BSA‐GNPs) conjugates as chiral stationary phases for capillary electrochromatography (CEC). The bare monolithic column was prepared by a sol–gel process and has been chemically 3‐mercaptopropyltrimethoxysilane to provide thiol groups, followed immobilization gold via formation an Au‐S bond modification BSA selector nitrogen lone pair electrons. It demonstrated that can be...

10.1002/jssc.201100102 article EN Journal of Separation Science 2011-05-05

A wearable, low-cost, highly repeatable piezoresistive sensor was fabricated by the synthesis of modified-graphite and polyurethane (PU) composites polydimethylsiloxane (PDMS). Graphite sheets functionalized using a silane coupling agent (KH550) were distributed in PU/N,N-dimethylformamide (DMF) solution, which then molded to modified-graphite/PU (MG/PU) composite films. Experimental results show that with increasing content, tensile strength MG/PU films first increased decreased, elongation...

10.3390/ma10070684 article EN Materials 2017-06-22

Excessive fructose consumption is closely linked to the pathogenesis of metabolic disease. Carbohydrate response element-binding protein (ChREBP) a transcription factor essential for tolerance in mice. However, functional significance liver ChREBP metabolism remains unclear. Here, we show that protects mice against fructose-induced hepatotoxicity by regulating glycogen and ATP homeostasis. Liver-specific ablation did not compromise tolerance, but rather caused severe transaminitis...

10.2337/db19-0388 article EN Diabetes 2020-01-23

Herein, a facile strategy was proposed to fabricate lightweight polyimide-derived carbon foams (PICFs) with anisotropic pore structures which possess multifunctional properties enabling potential applications in high-end engineering sectors.

10.1039/d3tc02404k article EN Journal of Materials Chemistry C 2023-01-01

Abstract Liver has a unique regenerative capacity, however, its regulatory mechanism is not fully defined. We have established the zinc-finger protein ZBTB20 as key transcriptional repressor for alpha-fetoprotein (AFP) gene in liver. As marker of hepatic differentiation, AFP expression closely associated with hepatocyte proliferation. Unexpectedly, here we showed that acts positive regulator replication and required efficient liver regeneration. The mice specifically lacking hepatocytes...

10.1038/s41419-018-0514-0 article EN cc-by Cell Death and Disease 2018-04-23

This study was conducted to explore whether the effect of edaravone (5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol3-one, EDR) can ameliorate renal warm ischemia-reperfusion injury (IRI) by modulating endoplasmic reticulum stress (ERS) and its downstream effector after cardiac arrest (CA) cardiopulmonary resuscitation (CPR) in a rat model.The rats (n=10) experienced anaesthesia intubation followed no CA inducement were defined as Sham group. Transoesophageal alternating current stimulation...

10.2147/dddt.s211906 article EN cc-by-nc Drug Design Development and Therapy 2020-01-01
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