Uroš Bumbaširević

ORCID: 0000-0003-0367-2745
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About
Contact & Profiles
Research Areas
  • Bladder and Urothelial Cancer Treatments
  • Testicular diseases and treatments
  • Urinary and Genital Oncology Studies
  • Prostate Cancer Diagnosis and Treatment
  • COVID-19 and healthcare impacts
  • Urologic and reproductive health conditions
  • Cardiac, Anesthesia and Surgical Outcomes
  • Urological Disorders and Treatments
  • Inflammatory Biomarkers in Disease Prognosis
  • Prostate Cancer Treatment and Research
  • Glutathione Transferases and Polymorphisms
  • Cancer, Lipids, and Metabolism
  • Genital Health and Disease
  • Renal cell carcinoma treatment
  • Esophageal Cancer Research and Treatment
  • Radiation Dose and Imaging
  • Kidney Stones and Urolithiasis Treatments
  • Ultrasound in Clinical Applications
  • Genomics, phytochemicals, and oxidative stress
  • Trauma and Emergency Care Studies
  • Ovarian cancer diagnosis and treatment
  • Epigenetics and DNA Methylation
  • Health Systems, Economic Evaluations, Quality of Life
  • Pediatric Urology and Nephrology Studies
  • Sexual function and dysfunction studies

University of Belgrade
2015-2025

Univerzitetski Klinički Centar Srbije
2016-2024

Institut de Virologie
2020-2022

Centar za Promociju Nauke
2011-2021

University of Birmingham
2020

AstraZeneca (Brazil)
2020

Stryker (United Kingdom)
2020

Pfizer (United Kingdom)
2020

Merck (Germany)
2020

University of Belgrade – Faculty of Medicine
2020

Background and Objectives: Stress urinary incontinence (SUI) impacts 4–50% of adult women, frequently resulting in embarrassment, diminished self-esteem, social withdrawal, significantly affecting quality life. The aim our study is to cross-culturally adapt validate the Urinary Incontinence Outcome Questionnaire (IOQ) for Serbian population assess multifaceted impact SUI on life among women. Materials Methods: A cross-sectional involved a total 150 women: 100 undergoing surgical management...

10.3390/medicina61030509 article EN cc-by Medicina 2025-03-16

To assess the oncologic and functional outcomes of testicular sparing surgery (TSS) based on a single institution experience.Forty-one patients with bilateral 3 solitary testicle tumors were referred to our institution. The inclusion criteria for TSS normal serum testosterone levels, tumor size (<2 cm). Sperm analysis hormone status evaluation performed preoperatively postoperatively. None underwent local radiation therapy following reasons fertility preservation.A total 26 in 24 patients....

10.1002/jso.23777 article EN Journal of Surgical Oncology 2014-09-05

Background and Objectives To evaluate the results of testis‐sparing surgery (TSS) in patients, with small testicular lesions a normal contralateral testicle. Methods In all, 28 patients were treated TSS for was considered smaller than 2 cm no evidence metastatic disease. Results The mean age 35.3 ± 7.3 years, while diameter 11.4 3.7 mm. After pathological examination, 18 (64.3%) diagnosed stromal tumors miscellaneous lesions, 10 (35.7%) had germ cell tumor. median follow‐up time former group...

10.1002/jso.24502 article EN Journal of Surgical Oncology 2017-02-13

Background and Objectives: One of the most frequent genetic alterations reported to date in prostate cancer (PC) is aberrant methylation glutathione transferase P1 (GSTP1). Taking into consideration involvement oxidative stress PC pathogenesis recent advances scientific understanding role GSTP1*Ala114Val rs1138272 polymorphism carcinogenesis, we hypothesized that this single-nucleotide (SNP) influences risk independently of, or combination with, other GST polymorphisms, including...

10.3390/medicina56030128 article EN cc-by Medicina 2020-03-13

Study Type – Therapy (case series) Level of Evidence 4 What's known on the subject? and What does study add? Tumour location has been shown to be prognostic importance in UUT‐TCC, with tumours renal pelvis having a better prognosis than ureteral tumours. Patients from Balkan Endemic Nephropathy (BEN) areas had higher frequency Also, we found that belonging BEN area is an independent predictor disease recurrence. OBJECTIVE To identify impact tumour recurrence survival patients who were...

10.1111/j.1464-410x.2011.10461.x article EN BJU International 2011-08-25

Sustained and dysregulated inflammation, concurrent tumor-induced immune suppression, oxidative stress are profoundly involved in cancer initiation, presentation, perpetuation. Within this prospective study, we simultaneously analyzed the preoperative indices of systemic inflammatory response representative byproducts DNA, protein, lipid damage with aim evaluating their clinical relevance among patients diagnosed testicular germ-cell tumors (GCT). In analytical cohort (n = 88, median age 34...

10.3390/jpm12050833 article EN Journal of Personalized Medicine 2022-05-20

Given the high cure-rate for testicular cancer (TC) and patients' young age, comprehensive evaluation of health-related quality life (HRQOL) is an important consideration in this patient population. The EORTC QLQ-TC26 questionnaire module has been developed to supplement QLQ-C30 assessing TC-specific HRQOL clinical trials routine practice. This international, multicentre phase IV validation study evaluated psychometric properties new module. enrolled patients from seven European countries....

10.1186/s12885-018-5036-8 article EN cc-by BMC Cancer 2018-11-12

The simultaneous analysis of redox biomarkers and polymorphisms encoding for regulatory catalytic antioxidant proteins was performed in order to evaluate their potential role the development testicular germ cell tumor (GCT), as well progression disease. NRF2 (rs6721961), GSTM3 (rs1332018), SOD2 (rs4880) GPX3 (rs8177412) were assessed 88 patients with GCT (52 seminoma) age-matched controls. plasma levels 8-hydroxy-2'-deoxyguanosine (8-OHdG), thiol groups activity glutathione peroxidase...

10.3390/cancers14041068 article EN Cancers 2022-02-20

PCNL is safe procedure which well tolerated, but as with any other surgical procedure, it associated a specific set of complications. There marked heterogeneity in reporting complication rates literature, and this problem was highlighted Ad Hoc EAU guidelines panel who recommended urgent creation uniform reproducible quality system. Modified Dindo-Clavien grading system today the most utilized classification for complications urology, standard PCNL.To analyze rate using modified our patients...

10.2298/aci1401051n article EN Acta chirurgica iugoslavica 2014-01-01

Members of the omega class glutathione transferases (GSTs), GSTO1, and GSTO2, catalyze a range reduction reactions as part antioxidant defense system. Polymorphisms genes encoding proteins resultant altered redox profile have already been associated with increased risk for testicular germ cell cancer (GCT) development. The aim this pilot study was to assess individual, combined, haplotype, cumulative effect GSTO1rs4925, GSTO2rs156697, GSTO2rs2297235 polymorphisms GCT development, in 88...

10.3390/life13061269 article EN cc-by Life 2023-05-27

There are limited data regarding the significance of multifocality in testicular cancer patients. This study evaluated relationship between and clinicopathological features determined at time radical orchiectomy. The involved 280 consecutive patients who underwent orchiectomy 2018 2023. Multifocality was defined as a distinct tumor focus characterized by group malignant cells > 1 mm, clearly differentiated from primary mass. Uni- multivariate logistic regression analyses were employed to...

10.3390/life14020257 article EN cc-by Life 2024-02-16

Background: Hemoglobin, Albumin, Lymphocyte, and Platelet Score (HALP) is an accessible score that easily reproducible from routine laboratory testing while also reflecting patients’ immune-nutritional status. Along with other immuno-nutritional scores, such as the Prognostic Nutrition Index (PNI), HALP has been associated a number of clinical pathological features. The goal our study was to evaluate prognostic utility PNI scores in testicular germ cell cancer (GCT) patients. Methods: This...

10.3390/diagnostics14192196 article EN cc-by Diagnostics 2024-10-01
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