A5011376324- Enzyme Catalysis and Immobilization
- Microbial Metabolic Engineering and Bioproduction
- Biochemical and biochemical processes
- Enzyme-mediated dye degradation
- Chemistry and Chemical Engineering
- Biotin and Related Studies
- Plant Surface Properties and Treatments
- Pesticide and Herbicide Environmental Studies
- Mesoporous Materials and Catalysis
- Viral Infectious Diseases and Gene Expression in Insects
- Microbial metabolism and enzyme function
- Biofuel production and bioconversion
- Fluid Dynamics and Mixing
- Carbon dioxide utilization in catalysis
- bioluminescence and chemiluminescence research
- Analytical Chemistry and Chromatography
- Carbon Dioxide Capture Technologies
- Electrohydrodynamics and Fluid Dynamics
- Minerals Flotation and Separation Techniques
- Electrochemical sensors and biosensors
- Innovative Microfluidic and Catalytic Techniques Innovation
Hamburg University of Technology
2018-2021
Universität Hamburg
2018-2021
University of Rostock
2015-2017
Abstract The application of enzymes presents a great advantage regarding highly selective reactions; however, it involves also challenges due to their sensitivity. Immobilization offers one strategy overcome those enabling enzyme stabilization, as well retention. In the present study, covalent attachment on hydrophilic amino‐functionalized carriers is found be most promising immobilization method for investigated reaction system. To achieve this, novel preparation silica particles with...
The sufficient provision of oxygen is mandatory for enzymatic oxidations in aqueous solution, however, process optimization this still a bottleneck that cannot be overcome with the established methods macrobubble aeration. Providing higher mass transfer performance through microbubble aerators, inefficient aeration can or improved. Investigating transport model protein results kL values related to applied airstream comparison Comparing aerators at identical 160 and 60 1/h, resulting 25 44...
Cascade reactions are the basis of life in nature and adapted to research industry an increasing manner. The focus this study is production high-value aromatic ester cinnamyl cinnamate, which can be applied flavors fragrances. A three-enzyme cascade was established realize synthesis, starting from corresponding aldehyde with situ cofactor regeneration a two-phase system. After characterization enzymes, screening different organic solvents carried out, whereby xylene found most suitable...
Abstract Biotechnological application of multiple enzymes in different phases for target compounds synthesis poses a significant challenge industrial process development. At the same time, growing demand natural flavors and fragrances opens up possibilities novel biotechnological processes to replace current chemical routes, with additional advantages such as avoiding harsh reaction conditions toxic chemicals, less by‐products system. Within complex processes, key unfolding their potential...
Abstract Carbon capture technology can be set up in combination with biocatalysis to utilize the bound CO 2 as substrate Kolbe‐Schmitt like enzymatic reaction. The exemplary whole cell biotransformation of catechol 2,3‐dihydroxybenzoic acid a triethanolamine‐mediated multiphase system shows increased equilibrium conversion. Apart from beneficial thermodynamics, inherent fluid properties triethanolamine is enabling easy application fine bubbles highly efficient gassing method minimize demand...
This work aims to emphasize the importance of scale-up in biotechnological research, order introduce more environmentally friendly bio-catalyzed processes industry. Here, a complex reference reaction system is investigated, and, for first time, successful synthesis cinnamyl cinnamate from aldehyde multiphase established. A multi-enzymatic cascade sequence with integrated co factor regeneration and situ intermediate separation applied. highly successfully implemented pilot-scale reactor...
Abstract BACKGROUND Spray congealing is investigated as a new innovative immobilization technique for biocatalysts. The realized by atomization of mixture melted carrier and the enzyme, which re‐solidifyed due to temperature decrease. This method needs neither organic solvents, nor difficult downstream processing after preparation. For encapsulation different matrices, long chain alcohols glyceryl derivatives, with melting points below 86 °C environmentally friendly properties, are chosen...
tiviert und die Produktion von Interferonen induziert [2].Im Folgenden wurden 2 3 -cGAMP dessen Derivate mithilfe cGAS synthetisiert.Die Enzymaktivita ¨t wurde nachgewiesen anhand Design of Experiments ein Modell erstellt, um den biokatalytischen Mechanismus Reaktionsoptima zu bestimmen
Biotechnological application of multiple enzymes in different phases for target compounds synthesis poses a significant challenge industrial process development. At the same time, growing demand natural flavors and fragrances opens up possibilities novel biotechnological processes to replace current chemical routes, with additional advantages such as avoiding harsh reaction conditions toxic chemicals, less by-products system. Within complex processes, key unfolding their potential bioprocess...