A5037529699- Microbial Metabolic Engineering and Bioproduction
- Enzyme Catalysis and Immobilization
- Biochemical and biochemical processes
- Chemistry and Chemical Engineering
- Catalysis for Biomass Conversion
- Mesoporous Materials and Catalysis
- Process Optimization and Integration
- Biofuel production and bioconversion
- Viral Infectious Diseases and Gene Expression in Insects
- Catalysis and Hydrodesulfurization Studies
- Electrochemical sensors and biosensors
- Analytical Chemistry and Chromatography
- Crystallization and Solubility Studies
Universität Hamburg
2018-2021
Hamburg University of Technology
2018-2021
Software (Spain)
2020
Abstract The application of enzymes presents a great advantage regarding highly selective reactions; however, it involves also challenges due to their sensitivity. Immobilization offers one strategy overcome those enabling enzyme stabilization, as well retention. In the present study, covalent attachment on hydrophilic amino‐functionalized carriers is found be most promising immobilization method for investigated reaction system. To achieve this, novel preparation silica particles with...
Cascade reactions are the basis of life in nature and adapted to research industry an increasing manner. The focus this study is production high-value aromatic ester cinnamyl cinnamate, which can be applied flavors fragrances. A three-enzyme cascade was established realize synthesis, starting from corresponding aldehyde with situ cofactor regeneration a two-phase system. After characterization enzymes, screening different organic solvents carried out, whereby xylene found most suitable...
Abstract Biotechnological application of multiple enzymes in different phases for target compounds synthesis poses a significant challenge industrial process development. At the same time, growing demand natural flavors and fragrances opens up possibilities novel biotechnological processes to replace current chemical routes, with additional advantages such as avoiding harsh reaction conditions toxic chemicals, less by‐products system. Within complex processes, key unfolding their potential...
Abstract Common methods for the chemical production of fatty aldehydes, widely applied as artificial flavors and fragrances, use fossil starting materials, harsh reaction conditions, hazardous chemicals. This contribution introduces a novel, environmentally friendly process preparation aldehydes from natural, renewable resource plant oil. It has successfully been shown that bringing acid into contact with zerovalent iron leads to reduction corresponding aldehyde. In this paper, three‐step is...
The increasing demand for fatty aldehydes as natural flavoring agents nowadays grapples with current production processes requiring harsh reaction conditions and hazardous chemicals. Our research group proved the concept of an innovative, sustainable process based on renewable plant oils aldehyde production: acids reduction via zerovalent iron. In this study, we present first time extensive supporting data characterizing metal particles used co-reactants core step reaction, varying...
This work aims to emphasize the importance of scale-up in biotechnological research, order introduce more environmentally friendly bio-catalyzed processes industry. Here, a complex reference reaction system is investigated, and, for first time, successful synthesis cinnamyl cinnamate from aldehyde multiphase established. A multi-enzymatic cascade sequence with integrated co factor regeneration and situ intermediate separation applied. highly successfully implemented pilot-scale reactor...
tiviert und die Produktion von Interferonen induziert [2].Im Folgenden wurden 2 3 -cGAMP dessen Derivate mithilfe cGAS synthetisiert.Die Enzymaktivita ¨t wurde nachgewiesen anhand Design of Experiments ein Modell erstellt, um den biokatalytischen Mechanismus Reaktionsoptima zu bestimmen
Biotechnological application of multiple enzymes in different phases for target compounds synthesis poses a significant challenge industrial process development. At the same time, growing demand natural flavors and fragrances opens up possibilities novel biotechnological processes to replace current chemical routes, with additional advantages such as avoiding harsh reaction conditions toxic chemicals, less by-products system. Within complex processes, key unfolding their potential bioprocess...