- High Altitude and Hypoxia
- Muscle metabolism and nutrition
- Sports Performance and Training
- Cardiovascular and exercise physiology
- Hormonal and reproductive studies
- Cardiovascular Effects of Exercise
- Erythropoietin and Anemia Treatment
- Doping in Sports
- Sports injuries and prevention
- Exercise and Physiological Responses
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Thermoregulation and physiological responses
- Hemoglobin structure and function
- Hemoglobinopathies and Related Disorders
- Viral-associated cancers and disorders
- Lymphoma Diagnosis and Treatment
- Travel-related health issues
- Climate Change and Health Impacts
- Genetics and Physical Performance
- Parvovirus B19 Infection Studies
- Muscle and Compartmental Disorders
- Erythrocyte Function and Pathophysiology
- Sports Analytics and Performance
- Iron Metabolism and Disorders
- Neuroscience of respiration and sleep
Qatar Orthopaedic and Sports Medicine Hospital
2016-2025
University of Helsinki
2020
Research Institute for Olympic Sports
2020
University of Jyväskylä
2020
University Medical Center Freiburg
2003-2014
Anti-Doping Laboratory
2014
University of Freiburg
2004-2013
Qatar Airways (Qatar)
2013
Observatoire Cantonal de Neuchâtel
2011
Committee on Publication Ethics
2010
Alterations of the red blood cell system and iron metabolism can influence physical performance. On other hand, exercise hematological variables. The purpose this epidemiological study was to investigate characteristics in athletes different sporting disciplines at levels performance.We studied 851 male subjects (747 athletes, 104 untrained controls). Hemoglobin (Hb), hematocrit (Hct), count (RBC), iron, transferrin, ferritin (Fer), haptoglobin were analyzed standardized samples, obtained...
To characterise the core temperature response and power output profile of elite male female cyclists during 2016 UCI Road World Championships. This may contribute to formulating environmental heat stress policies.Core was recorded via an ingestible capsule in 10, 15 team time trial (TTT), individual (ITT) road race (RR), respectively. Power heart rate were extracted from cycling computers. Ambient conditions direct sunlight hot (37°C±3°C) but dry (25%±16% relative humidity), corresponding a...
Objectives The risk of viral transmission associated with contact sports such as football (soccer) during the COVID-19 pandemic is unknown. aim this study was to describe infective and immune status professional players, team staff league officials over a truncated season resumed at height in country high infection rates investigate clinical symptoms related players. Methods Prospective cohort 1337 (9 weeks) tailored control programme based on preventive measures regular SARS-CoV-2 PCR swab...
Despite the limited research on effects of altitude (or hypoxic) training interventions team-sport performance, players from all around world engaged in these sports are now using more than ever before. In March 2013, an Altitude Training and Team Sports conference was held Doha, Qatar, to establish a forum practical insights into this rapidly growing field. A round-table meeting which panellists focused discussions concluded conference. This has resulted present position statement, designed...
This study aims at describing the workload demands during mountain bike races using direct power measurements, and to compare these data output physiological findings from laboratory exercise tests. Power (P, Watt) 11 national team cyclists (9 male, 2 female) was registered continuously 15 mobile crank dynamometers (SRM System). To evaluate intensity of racing, incremental tests with determination P aerobic anaerobic thresholds (AT, IAT) exhaustion (MAX) were performed. Intensity zones...
The aim of the study was to evaluate power output during a multistage professional road race using direct measurements and compare these results with performance competition heart rate recordings.Six cyclists performed an incremental cycling test which peak output, at lactate threshold (LT) increase 1 mM above LT (LT + 1) were assessed. During six-stage competition, measured directly (SRM crankset). To analyze time spent different intensities amount below (zone 1), between 2), 3) determined...
All kinds of blood manipulations aim to increase the total hemoglobin mass (tHb-mass). To establish tHb-mass as an effective screening parameter for detecting doping, knowledge its normal variation over time is necessary. The present study, therefore, was determine intraindividual variance in elite athletes during a training year emphasizing off, training, and race seasons at sea level.tHb-mass concentration ([Hb]) were determined 24 endurance five times compared with control group (n = 6)....
Acute illnesses affecting the respiratory tract are common and form a significant component of work Sport Exercise Medicine (SEM) clinicians. illness (ARill) can broadly be classified as non-infective ARill acute infections (ARinf). The aim this consensus is to provide SEM clinician with an overview practical clinical approach ARinf in athletes. International Olympic Committee (IOC) Medical Scientific Commission appointed international group review (non-infective ARinf) Six subgroups IOC...
Background The Aspetar Sports Injury and Illness Prevention Programme introduced the IP 2 NetWork, a customizable injury prevention programme for professional football clubs in Qatar during 2020/2021 season. It includes 23 focus areas selected by stakeholders to prevent sports-related health issues. Objective To assess real world implementation of NetWork preventive first season after introduction, focusing on team adoption player compliance. Methods A survey was conducted among physicians,...
Blood donation plays an important role in every health care system. Measurement of hemoglobin (Hb) concentration or hematocrit to assess hematologic recovery after may not adequately reflect the true amount blood as they are affected by plasma volume fluctuations. Instead, total Hb mass (tHb) is variable choice and can be determined routine clinical practice. Therefore, purpose was investigate tHb standard donation.The optimized CO rebreathing method used for evaluation before 1-unit...
The development of peak performances is a main research focus in sports science. It unclear how many former top junior athletes achieve success the elite class later. aim present study was to examine careers who participated major or adult/elite cycling events using prospective and retrospective analysis competition results. official results (age < = 18 years) > races from 1980 2004 were analysed. Age-related aspects, career lengths, compared between riders presented both (JUNIOR ELITE) had...
BACKGROUND: Since no direct detection method for autologous blood transfusions exists, the most promising attempt is Athlete Biological Passport (ABP) and its adaptive model that enables a longitudinal monitoring of hematologic measures to identify patterns manipulations. The purpose therefore was evaluate performance this in blinded setting. STUDY DESIGN AND METHODS: Twenty‐one subjects were divided into doped group (multiple 1‐2 units red cells, n = 11) control (n 10). time course cycling...
MicroRNAs (miRNAs) are small non-coding RNAs that regulate various biological processes. Cell-free miRNAs measured in blood plasma have emerged as specific and sensitive markers of physiological processes disease. In this study, we investigated whether circulating can serve biomarkers for the detection autologous transfusion, a major doping technique is still undetectable. Plasma miRNA levels were analyzed using high-throughput quantitative real-time PCR. samples obtained before at several...
Acute respiratory illness (ARill) is common and threatens the health of athletes. ARill in athletes forms a significant component work Sport Exercise Medicine (SEM) clinicians. The aim this consensus to provide SEM clinician with an overview practical clinical approach non-infective International Olympic Committee (IOC) Medical Scientific appointed international group review Key areas were originally identified six subgroups IOC Consensus established following aspects: (1) epidemiology/risk...
With the increased time of survival as a result improved prophylaxis and treatment AIDS, non-infectious conditions related to HIV are being detected more frequently. In addition well-known myocarditis cardiomyopathy, pulmonary hypertension represents another HIV-induced cardiovascular complication with very poor prognosis: The median interval between diagnosis in patients death is only 6 months [1]. pathophysiology HIV-related still unknown. As histopathology shows similarities primary...
Expert evaluation of biological data is a key component the Athlete Biological Passport approach in fight against doping. The consists longitudinal assessment variables to determine probability being physiological on basis athlete's own previous values (performed by an automated software system using Bayesian model) and subjective results view possible causes experts). role expert therefore process. Experts should be qualified evaluate regarding explanations related influence doping products...
Until recently, the physiological demands of cycling competitions were mostly reflected by measurement heart rate and indirect estimation exercise intensity. The purpose this case study was to illustrate varying power output a professional cyclist during flat mountain stages Grand Tour (Giro d'Italia). Nine stage recordings 2005 Giro d'Italia monitored using mobile device (SRM Trainingssystem, Julich, Germany), which recorded direct rate. Stages categorized into (n = 5) 4). Data processed...
Haemoglobin mass is a main determinant of maximal oxygen uptake. Blood doping aims at increasing this variable. Limits for haematocrit and haemoglobin concentration are used as indicators blood doping. However, these variables measures concentration, do not represent total altered by vascular volumes shifts. Direct estimation could improve tests. It unknown if physical exercise alters mass. The purpose study was to investigate the reaction other compartments heavy in athletes. were evaluated...