A5051920282- Congenital Diaphragmatic Hernia Studies
- Neonatal Respiratory Health Research
- Cystic Fibrosis Research Advances
- Tracheal and airway disorders
- Congenital Heart Disease Studies
- Congenital Anomalies and Fetal Surgery
- Atomic and Subatomic Physics Research
- Autoimmune and Inflammatory Disorders Research
- Orthopedic Infections and Treatments
- Renal and Vascular Pathologies
- Hernia repair and management
- Streptococcal Infections and Treatments
- Transplantation: Methods and Outcomes
- Infectious Diseases and Tuberculosis
- Lung Cancer Diagnosis and Treatment
- Rheumatoid Arthritis Research and Therapies
- Pneumonia and Respiratory Infections
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Aortic aneurysm repair treatments
- Adolescent and Pediatric Healthcare
- Tumors and Oncological Cases
- Respiratory viral infections research
- Pleural and Pulmonary Diseases
- Vascular anomalies and interventions
- Ultrasound in Clinical Applications
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2016-2025
Medizinische Hochschule Hannover
2024
Ospedale Maggiore
2015-2021
Fondazione Santa Lucia
2021
ORCID
2021
University of Insubria
2021
University of Milan
2016-2017
Children's Hospital Agia Sophia
2015
University of Ferrara
2010
University Hospital of Geneva
2008
Please cite this paper as: Esposito et al. (2012) Impact of viral infections in children with community‐acquired pneumonia: results a study 17 respiratory viruses. Influenza and Other Respiratory Viruses DOI: 10.1111/j.1750‐2659.2012.00340.x. Background Little is known about the prevalence pneumonia (CAP). Objectives To describe clinical virological data collected from radiographically confirmed CAP whom viruses were sought secretion samples during acute phase disease. Patients methods The...
There are few prospective evaluations of point-of-care ultrasonography (US) for the diagnosis pediatric community-acquired pneumonia (CAP). In particular, there very data concerning efficiency US in comparison with that chest radiography (CR) defining different kinds lung alterations various pulmonary sections. The aim this study was to bridge gap order increase our knowledge performance diagnosing CAP childhood. A total 103 children (56 males, 54.4%; mean age ± standard deviation 5.6 4.6...
Abstract Prenatal assessment of lung size and liver position is essential to stratify congenital diaphragmatic hernia (CDH) fetuses in risk categories, guiding counseling, patient management. Manual segmentation on fetal MRI provides a quantitative estimation total volume herniation. However, it time-consuming operator-dependent. In this study, we utilized publicly available deep learning (DL) system (nnU-Net) automatically contour CDH-affected lungs sections. Concordance between automatic...
Lymphatic malformations (LMs) are rare and benign anomalies resulting from the defective embryological development of primordial lymphatic structures. Due to their permeative growth throughout all tissue layers, treatment is often challenging. Small asymptomatic lesions can be conservatively managed, while symptomatic require active management. Surgery has been historically considered choice, but today less invasive therapeutic options preferred (sclerotherapy, laser therapy, oral...
Abstract Background Atraumatic avascular necrosis (AVN) is a severe condition that may complicate the course of rheumatic diseases and contribute to long-term damage. However, there lack evidence on this rare event in pediatric rheumatology. The aim our study was evaluate occurrence context rheumatologic Italy describe main demographic clinical features AVN patients, with particular focus treatment background. Methods All centres part Italian Society Pediatric Rheumatology were invited...
Abstract Congenital diaphragmatic hernia (CDH) has high morbidity and mortality rates. This study aimed to develop a machine learning (ML) algorithm predict outcomes based on prenatal early postnatal data. retrospective observational cohort involved infants with left-sided CDH, born from 2012 2020. We analyzed clinical imaging data using three classification algorithms: XGBoost, Support Vector Machine, K -Nearest Neighbors. Medical records of 165 pregnant women CDH fetal diagnosis were...
Background: Bronchopulmonary sequestration (BPS) is a portion of dysplastic pulmonary tissue not communicating with the tracheobronchial tree. Its vascularization provided by abnormal arteries originating from systemic circulation. Previous papers report different venous drainage (VD) between intralobar (ILS) and extralobar (ELS), respectively, into or veins. The aim our study to investigate VD as independent predictor type PS. Methods: We retrospectively reviewed 41 pediatric patients who...
Introduction Outcome predictions of patients with congenital diaphragmatic hernia (CDH) still have some limitations in the prenatal estimate postnatal pulmonary hypertension (PH). We propose applying Machine Learning (ML), and Deep (DL) approaches to fetuses newborns CDH develop forecasting models epoch, based on integrated analysis clinical data, provide neonatal PH as first outcome and, possibly: favorable response fetal endoscopic tracheal occlusion (FETO), need for Extracorporeal...
<b><i>Aim:</i></b> To evaluate tracheal diameters and their clinical impact in patients with congenital diaphragmatic hernia (CDH) after fetal endoscopic occlusion (FETO). <b><i>Methods:</i></b> Patients born CDH between January 2012 August 2016 were divided into two groups: noFETO FETO. Tracheal at three levels (T1, carina, maximum dilation) on chest X-ray 1, 3, 6, 12, 24, 36 months of follow-up, requirements invasive noninvasive respiratory...
Polymorphisms of the interleukin-1 (IL-1) gene family have been proposed as potential variants for different diseases including multiple sclerosis (MS). With respect to MS, IL-1 beta (-511 C/T; rs16944), (+3954 rs1143634), alpha (-889 rs1800587), (+4845 G/T; rs17561), and variable number tandem repeats in intron 2 receptor antagonist (IL-1RN) polymorphisms studied ethnic groups, leading conflicting results.This study investigates association between genes MS by means 70 markers spanning 1.1...
The interleukin-1 (IL-1) gene family has been associated with susceptibility to periodontal diseases, including aggressive periodontitis (AgP); however, the results are still conflicting. present study investigated association between IL-1 genes and AgP using 70 markers spanning 1.1-Mb region, where maps, exploring both linkage disequilibrium (LD) haplotype structure in a case-control 95 patients 121 control individuals. No IL1A, IL1B, IL1RN was found either single-point or analyses. Also,...
Congenital diaphragmatic hernia is a rare disease with high mortality and morbidity due to pulmonary hypoplasia hypertension. The aim of the study investigate relationship between radiographic lung area systolic artery pressure (sPAP) on first day life, mortality, recurrence during year life in infants congenital (CDH). A retrospective data collection was performed 77 CDH newborns. Echocardiographic sPAP value, deaths, cases were recorded. Lung calculated by tracing lung's perimeter,...
This cross-sectional study aims to verify the relationship between quantitative multivolume proton-magnetic resonance imaging (1H-MRI) and clinical indicators of ventilatory abnormalities in cystic fibrosis (CF) lung disease.Non-enhanced chest MRI, spirometry multiple breath washout was performed by 28 patients (10-27 years) with CF disease. Images acquired at end-inspiration end-expiration were registered optical flow estimate expiratory-inspiratory proton-density change (Δ1H-MRI) as a...
Double gallbladder is a rare biliary anomaly. Perinatal diagnosis of the disorder has been reported in only 6 cases, and 5 them was based on ultrasound imaging only. However, technique alone does not provide sufficiently precise description cystic ducts anatomy, an information that crucial for correct classification possible future surgery.At 21 weeks gestational age uneventful pregnancy 38 year old primipara mother, routine screening detected anomaly fetus suggestive double gallbladder. A...
Abstract Introduction Consensus on the best postnatal radiological evaluation of congenital lung malformations (CLMs) is still lacking. In recent years, interest magnetic resonance imaging (MRI) has grown, but its role unknown. Aim The aim study was to identify preoperative diagnostic assessment for CLM. Materials and Methods All patients with a prenatal suspicion CLM between January 2014 February 2018 were studied. Asymptomatic newborns underwent MRI, during spontaneous sleep without...
Rib osteomyelitis is a rare entity, occurring in approximately 1 % or less of all cases haematogenous osteomyelitis. Given its rarity and clinical heterogeneity, the diagnosis rib can be challenging requires high index suspicion. We present case acute due to community-acquired methicillin-resistant Staphylococcus aureus (MRSA), which occurred an otherwise healthy 3-month-old infant mimicked epigastric hernia at first. An female was sent by her primary care paediatrician paediatric emergency...